UA129888C2 - Спосіб одержання енантіомерно та діастереомерно збагачених циклобутанамінів та -амідів - Google Patents

Спосіб одержання енантіомерно та діастереомерно збагачених циклобутанамінів та -амідів

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Publication number
UA129888C2
UA129888C2 UAA202003527A UAA202003527A UA129888C2 UA 129888 C2 UA129888 C2 UA 129888C2 UA A202003527 A UAA202003527 A UA A202003527A UA A202003527 A UAA202003527 A UA A202003527A UA 129888 C2 UA129888 C2 UA 129888C2
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UA
Ukraine
Prior art keywords
formula
compound
bis
c6alkyl
reaction mixture
Prior art date
Application number
UAA202003527A
Other languages
English (en)
Ukrainian (uk)
Inventor
Рафаель Дюмьоньє
Рафаель Дюмьонье
Томас Смейкал
Томас Смэйкал
Бріджнандан Премнат Мішра
Бриджнандан Премнат Мишра
Віджаягопал Роман Гопалсамутірам
Виджаягопал Роман Гопалсамутирам
Едуар Годіно
Эдуар Годино
Ентоні Корнеліус О'Салліван
Энтони Корнелиус О'САЛЛИВАН
Original Assignee
Сінгента Кроп Протекшн Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сінгента Кроп Протекшн Аг filed Critical Сінгента Кроп Протекшн Аг
Publication of UA129888C2 publication Critical patent/UA129888C2/uk

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/02Boron or aluminium; Oxides or hydroxides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/06Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/06Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • C07C231/065By hydration using metals or metallic ions as catalyst
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/44Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/38Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/457Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/39Saturated compounds containing a keto group being part of a ring of a three- or four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/457Saturated compounds containing a keto group being part of a ring containing halogen
    • C07C49/467Saturated compounds containing a keto group being part of a ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/593Unsaturated compounds containing a keto groups being part of a ring of a three- or four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/647Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/803Processes of preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/57Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/58Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)
UAA202003527A 2017-11-16 2018-11-14 Спосіб одержання енантіомерно та діастереомерно збагачених циклобутанамінів та -амідів UA129888C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201711041030 2017-11-16
PCT/EP2018/081257 WO2019096860A1 (en) 2017-11-16 2018-11-14 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides

Publications (1)

Publication Number Publication Date
UA129888C2 true UA129888C2 (uk) 2025-09-03

Family

ID=64316566

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA202003527A UA129888C2 (uk) 2017-11-16 2018-11-14 Спосіб одержання енантіомерно та діастереомерно збагачених циклобутанамінів та -амідів

Country Status (15)

Country Link
US (1) US11053188B2 (https=)
EP (1) EP3710422B1 (https=)
JP (1) JP7337797B2 (https=)
KR (1) KR102732899B1 (https=)
CN (1) CN111417618B (https=)
AU (1) AU2018367119B2 (https=)
CA (1) CA3082558A1 (https=)
CO (1) CO2020005806A2 (https=)
ES (1) ES3061224T3 (https=)
IL (1) IL274654B2 (https=)
MX (1) MX2020004884A (https=)
SG (1) SG11202003259WA (https=)
TW (1) TWI787391B (https=)
UA (1) UA129888C2 (https=)
WO (1) WO2019096860A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202513532A (zh) * 2023-09-15 2025-04-01 瑞士商先正達農作物保護股份公司 用於製備鏡像異構物富集的脂肪族胺之方法
WO2026003324A1 (en) 2024-06-27 2026-01-02 Syngenta Crop Protection Ag Pesticidal mixtures
WO2026003323A1 (en) 2024-06-27 2026-01-02 Syngenta Crop Protection Ag Pesticidal mixtures
WO2026003327A1 (en) 2024-06-27 2026-01-02 Syngenta Crop Protection Ag Pesticidal mixtures
WO2026003326A1 (en) 2024-06-27 2026-01-02 Syngenta Crop Protection Ag Pesticidal mixtures
WO2026003322A1 (en) 2024-06-27 2026-01-02 Syngenta Crop Protection Ag Pesticidal mixtures
WO2026017904A1 (en) 2024-07-19 2026-01-22 Syngenta Crop Protection Ag Pesticidal mixture
WO2026017903A1 (en) 2024-07-19 2026-01-22 Syngenta Crop Protection Ag Pesticidal mixture
WO2026017896A1 (en) 2024-07-19 2026-01-22 Syngenta Crop Protection Ag Mixtures for controlling infestation of plants

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GB9304191D0 (en) * 1993-03-02 1993-04-21 Ciba Geigy Ag Process for the preparation of aqueous nicotinaldehyde
US6342644B1 (en) 2000-05-10 2002-01-29 Takasago International Corporation Method for producing 1-menthol
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
US6476235B2 (en) * 2001-01-09 2002-11-05 Warner-Lambert Company Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
CA2648246C (en) * 2006-04-03 2014-02-18 F. Hoffmann-La Roche Ag Process for preparation of enantiomerically enriched cyclic .beta.-aryl or heteroaryl carboxylic acids
US8143280B2 (en) * 2007-09-27 2012-03-27 Hoffmann-La Roche Inc. Glucocorticoid receptor antagonists
TW201332947A (zh) * 2011-11-04 2013-08-16 Syngenta Participations Ag 殺有害生物之化合物
EP2644595A1 (en) 2012-03-26 2013-10-02 Syngenta Participations AG. N-Cyclylamides as nematicides
UY35543A (es) * 2013-04-30 2014-11-28 Bayer Cropscience Ag N-(fenilcicloalquil)carboxamidas y n-(fenilcicloalquil)tiocarboxamidas nematicidas
USRE50724E1 (en) * 2013-07-08 2026-01-06 Syngenta Crop Protection Ag 4-membered ring carboxamides used as nematicides
WO2015178846A1 (en) * 2014-05-20 2015-11-26 Sp Process Development Ab Process for the preparation of chiral amines from prochiral ketones
CN106661074A (zh) * 2014-07-31 2017-05-10 桑多斯股份公司 磷酰胺的合成

Also Published As

Publication number Publication date
TWI787391B (zh) 2022-12-21
MX2020004884A (es) 2020-08-06
CA3082558A1 (en) 2019-05-23
IL274654B1 (en) 2023-07-01
US20200407311A1 (en) 2020-12-31
AU2018367119B2 (en) 2023-05-11
IL274654B2 (en) 2023-11-01
CN111417618B (zh) 2023-06-30
EP3710422C0 (en) 2026-01-07
BR112020009787A2 (pt) 2020-11-03
AU2018367119A1 (en) 2020-06-04
EP3710422A1 (en) 2020-09-23
KR20200083995A (ko) 2020-07-09
EP3710422B1 (en) 2026-01-07
CN111417618A (zh) 2020-07-14
ES3061224T3 (en) 2026-03-31
RU2020118927A (ru) 2021-12-16
US11053188B2 (en) 2021-07-06
CO2020005806A2 (es) 2020-05-29
WO2019096860A1 (en) 2019-05-23
SG11202003259WA (en) 2020-05-28
JP7337797B2 (ja) 2023-09-04
JP2021503470A (ja) 2021-02-12
KR102732899B1 (ko) 2024-11-20
IL274654A (en) 2020-06-30
TW201936558A (zh) 2019-09-16

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