UA126195C2 - Водна композиція, яка містить атропін - Google Patents

Водна композиція, яка містить атропін Download PDF

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Publication number
UA126195C2
UA126195C2 UAA201812662A UAA201812662A UA126195C2 UA 126195 C2 UA126195 C2 UA 126195C2 UA A201812662 A UAA201812662 A UA A201812662A UA A201812662 A UAA201812662 A UA A201812662A UA 126195 C2 UA126195 C2 UA 126195C2
Authority
UA
Ukraine
Prior art keywords
aqueous composition
buffer
composition according
atropine
phosphate
Prior art date
Application number
UAA201812662A
Other languages
English (en)
Ukrainian (uk)
Inventor
Дональд Тан
Роджер Бойєрман
Роджер Бойерман
Хіроюкі Асада
Хироюки АСАДА
Кіохеї Такахасі
Киохеи Такахаси
Кодзі Саканака
Кодзи Саканака
Такасі Морімото
Такаси МОРИМОТО
Тойомі Фудзісава
Тойоми Фудзисава
Original Assignee
Сінгапур Хелт Сервісіз Пте Лтд
Сингапур Хелт Сервисиз Пте Лтд
Наньян Текнолоджікал Юніверсіті
Наньян Текнолоджикал Юниверсити
Сантен Фармасьютікал Ко., Лтд.
Сантен Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60411416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA126195(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Сінгапур Хелт Сервісіз Пте Лтд, Сингапур Хелт Сервисиз Пте Лтд, Наньян Текнолоджікал Юніверсіті, Наньян Текнолоджикал Юниверсити, Сантен Фармасьютікал Ко., Лтд., Сантен Фармасьютикал Ко., Лтд. filed Critical Сінгапур Хелт Сервісіз Пте Лтд
Publication of UA126195C2 publication Critical patent/UA126195C2/uk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Materials For Photolithography (AREA)
UAA201812662A 2016-05-25 2017-05-24 Водна композиція, яка містить атропін UA126195C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201604200P 2016-05-25
PCT/JP2017/019423 WO2017204262A1 (en) 2016-05-25 2017-05-24 Atropine-containing aqueous composition

Publications (1)

Publication Number Publication Date
UA126195C2 true UA126195C2 (uk) 2022-08-31

Family

ID=60411416

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201812662A UA126195C2 (uk) 2016-05-25 2017-05-24 Водна композиція, яка містить атропін

Country Status (15)

Country Link
US (2) US20210267885A1 (OSRAM)
EP (2) EP3463360B1 (OSRAM)
JP (6) JP6590860B2 (OSRAM)
KR (4) KR102804061B1 (OSRAM)
CN (3) CN109310687B (OSRAM)
AR (1) AR108591A1 (OSRAM)
CA (1) CA3023149C (OSRAM)
EA (1) EA201892703A1 (OSRAM)
ES (1) ES2929368T3 (OSRAM)
MY (1) MY189774A (OSRAM)
PH (1) PH12018502421A1 (OSRAM)
SG (1) SG11201809822SA (OSRAM)
TW (3) TWI791438B (OSRAM)
UA (1) UA126195C2 (OSRAM)
WO (1) WO2017204262A1 (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
WO2016172712A2 (en) * 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
WO2016196367A1 (en) 2015-05-29 2016-12-08 Sydnexis, Inc. D2o stabilized pharmaceutical formulations
KR20200007769A (ko) * 2017-02-21 2020-01-22 싱가포르 헬스 서비시즈 피티이 엘티디 아트로핀을 포함하는 근시의 발병을 방지 또는 지연하기 위한 조성물 및 방법
HRP20212019T1 (hr) 2017-05-11 2022-04-01 Vyluma Inc. Atropinski farmaceutski sastavi
CN114557955B (zh) * 2018-09-25 2024-06-18 沈阳兴齐眼药股份有限公司 药物组合物、其制备方法和用途
CN110934869B (zh) * 2018-09-25 2023-07-04 沈阳兴齐眼药股份有限公司 一种阿托品药物组合物和药盒产品
EP3701938B8 (en) 2019-03-01 2024-02-21 Medivis S.R.L. Ophthalmic formulations based on atropine
AU2021320350A1 (en) 2020-08-04 2023-02-09 Boehringer Ingelheim International Gmbh Agent for treating myopia, preventing myopia and/or suppressing myopia progression
KR20230087514A (ko) * 2020-10-14 2023-06-16 산텐 세이야꾸 가부시키가이샤 안정한 의약 조성물
JP2023548605A (ja) 2020-11-02 2023-11-17 トレセラ コーポレーション デオキシシチジンキナーゼ阻害剤の結晶形態およびその使用
WO2022130337A1 (en) * 2020-12-17 2022-06-23 Sun Pharmaceutical Industries Limited An aqueous sterile solution of atropine for ophthalmic use
EP4088714A1 (en) 2021-05-10 2022-11-16 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic pharmaceutical composition comprising atropine
EP4088713A1 (en) 2021-05-10 2022-11-16 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic pharmaceutical composition comprising atropine
US20230120997A1 (en) * 2021-10-18 2023-04-20 Ocular Science, Inc. Compositions and methods for myopia control and orthokeratology lenses treatment
CN114129511A (zh) * 2021-12-07 2022-03-04 河南润弘制药股份有限公司 一种具有改进稳定性的硫酸阿托品注射液
CN119110721A (zh) * 2022-09-11 2024-12-10 爱尔康公司 包含苄基阿托品的水性药物组合物及其用途
JP7665073B1 (ja) 2024-04-05 2025-04-18 ロート製薬株式会社 容器に収容してなる眼科用組成物
JP7723851B1 (ja) * 2024-11-22 2025-08-14 参天製薬株式会社 アトロピン含有水性医薬組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2617508B2 (ja) * 1988-02-05 1997-06-04 エーザイ株式会社 安定なジフェンヒドラミン含有水溶液
JP3166002B2 (ja) * 1997-01-27 2001-05-14 日本車輌製造株式会社 自動車の洗浄装置
US20030096831A1 (en) 2000-01-18 2003-05-22 Stone Richard A. Ocular growth and nicotinic antagonists
NZ529615A (en) * 2001-05-25 2005-07-29 Valley Forge Pharmaceuticals Pirenzepine ophthalmic gel
US20070254914A1 (en) * 2006-05-01 2007-11-01 Non-Profit Organization Chang Gung Memorial Hospital Low-concentration atropine solution for preventing myopia progression and preparing method thereof
JP2007308398A (ja) * 2006-05-17 2007-11-29 Chang Gung Memorial Hospital 目薬、及びその製造方法
AU2008254428A1 (en) * 2007-05-21 2008-11-27 Neuroptix Corporation Ophthalmic formulations of Amyloid-beta contrast agents and methods of use thereof
CN101327216A (zh) * 2007-06-22 2008-12-24 肖正连 一种硫酸阿托品眼用即型凝胶
WO2012161655A1 (en) 2011-05-23 2012-11-29 Singapore Health Services Pte Ltd Composition and/or method for reducing and/or preventing myopia progression comprising atropine
US9421199B2 (en) * 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
US20160009705A1 (en) * 2014-06-24 2016-01-14 Sydnexis, Inc. Ophthalmic composition
JP2017102939A (ja) * 2016-12-26 2017-06-08 株式会社プロフィールド オーサリング装置、オーサリング方法、およびプログラム
HRP20212019T1 (hr) 2017-05-11 2022-04-01 Vyluma Inc. Atropinski farmaceutski sastavi

Also Published As

Publication number Publication date
JP2021120404A (ja) 2021-08-19
EP3463360A4 (en) 2020-01-29
TWI791438B (zh) 2023-02-11
TWI849355B (zh) 2024-07-21
CA3023149A1 (en) 2017-11-30
KR20190013877A (ko) 2019-02-11
CN117205210A (zh) 2023-12-12
JP2020007356A (ja) 2020-01-16
SG11201809822SA (en) 2018-12-28
CN117205209A (zh) 2023-12-12
CA3023149C (en) 2024-07-02
CN109310687B (zh) 2023-10-20
CN109310687A (zh) 2019-02-05
KR102804061B1 (ko) 2025-05-07
AR108591A1 (es) 2018-09-05
JP7224390B2 (ja) 2023-02-17
JP2023058574A (ja) 2023-04-25
TW202206070A (zh) 2022-02-16
US20210267885A1 (en) 2021-09-02
KR20250067951A (ko) 2025-05-15
EA201892703A1 (ru) 2019-04-30
JP2018021007A (ja) 2018-02-08
US20240307305A1 (en) 2024-09-19
PH12018502421A1 (en) 2019-09-30
TW202325296A (zh) 2023-07-01
KR102580933B1 (ko) 2023-09-19
MY189774A (en) 2022-03-04
TWI874894B (zh) 2025-03-01
TW201808289A (zh) 2018-03-16
JP6590860B2 (ja) 2019-10-16
EP3463360A1 (en) 2019-04-10
JP2025176149A (ja) 2025-12-03
WO2017204262A1 (en) 2017-11-30
JP6886502B2 (ja) 2021-06-16
EP4112055A1 (en) 2023-01-04
KR20230141882A (ko) 2023-10-10
KR20220154842A (ko) 2022-11-22
EP3463360B1 (en) 2022-08-31
ES2929368T3 (es) 2022-11-28
JP2025084921A (ja) 2025-06-03

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