UA117751C2 - Похідні тилозину і спосіб їх одержання - Google Patents

Похідні тилозину і спосіб їх одержання

Info

Publication number
UA117751C2
UA117751C2 UAA201512523A UAA201512523A UA117751C2 UA 117751 C2 UA117751 C2 UA 117751C2 UA A201512523 A UAA201512523 A UA A201512523A UA A201512523 A UAA201512523 A UA A201512523A UA 117751 C2 UA117751 C2 UA 117751C2
Authority
UA
Ukraine
Prior art keywords
derivatives
preparation
animal
treating
tylosin derivatives
Prior art date
Application number
UAA201512523A
Other languages
English (en)
Inventor
Герд Клефельд
Робрехт Фройман
Каролін Людвіг
Сатосі Омура
Тосіакі Сунадзука
Хіросе Томоясу
Сугавара Акіхіро
Сіомі Кадзуро
Original Assignee
Байєр Енімал Хелс Гмбх
Кітасато Інстітьют
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48463869&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA117751(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Байєр Енімал Хелс Гмбх, Кітасато Інстітьют filed Critical Байєр Енімал Хелс Гмбх
Publication of UA117751C2 publication Critical patent/UA117751C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Даний винахід стосується нових похідних макролідів, зокрема нових похідних тилозину формули (IIа), фармацевтичної або ветеринарої композиції, що містить ці похідні; способу їх одержання; способу лікування і/або профілактики бактеріальних інфекцій у тварин, причому спосіб включає введення похідних або композиції; і застосування похідних для виготовлення лікарських засобів для лікування і/або профілактики бактеріальних інфекцій у тварин.
UAA201512523A 2013-05-23 2014-05-23 Похідні тилозину і спосіб їх одержання UA117751C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13169009 2013-05-23
PCT/EP2014/060665 WO2014187957A1 (en) 2013-05-23 2014-05-23 Tylosin derivatives and method for preparation thereof

Publications (1)

Publication Number Publication Date
UA117751C2 true UA117751C2 (uk) 2018-09-25

Family

ID=48463869

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201512523A UA117751C2 (uk) 2013-05-23 2014-05-23 Похідні тилозину і спосіб їх одержання

Country Status (26)

Country Link
US (1) US9771389B2 (uk)
EP (1) EP2999707B1 (uk)
JP (1) JP6494600B2 (uk)
KR (1) KR102307218B1 (uk)
CN (1) CN105408340B (uk)
AU (1) AU2014270353B2 (uk)
BR (1) BR112015029260A2 (uk)
CA (1) CA2913098C (uk)
CL (1) CL2015003433A1 (uk)
DK (1) DK2999707T3 (uk)
ES (1) ES2669615T3 (uk)
HK (1) HK1216753A1 (uk)
HR (1) HRP20180877T1 (uk)
HU (1) HUE037868T2 (uk)
IL (1) IL242543B (uk)
MX (1) MX361808B (uk)
MY (1) MY184630A (uk)
NO (1) NO2999707T3 (uk)
PE (1) PE20160207A1 (uk)
PL (1) PL2999707T3 (uk)
PT (1) PT2999707T (uk)
RU (1) RU2714482C2 (uk)
SI (1) SI2999707T1 (uk)
TR (1) TR201809189T4 (uk)
UA (1) UA117751C2 (uk)
WO (1) WO2014187957A1 (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
CN110590885A (zh) * 2019-09-30 2019-12-20 郑州大学 20-取代-5-o-碳霉胺糖基-泰乐内酯衍生物
CN112898361A (zh) * 2021-02-01 2021-06-04 郑州大学 5-o-碳霉胺糖基泰乐内酯衍生物及其制备方法及应用
WO2023230702A1 (en) * 2022-06-03 2023-12-07 University Of Manitoba Novel antimicrobial compounds isolated using a machine learning model trained on a high-throughput antibacterial screen

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
IL69666A (en) * 1982-09-13 1987-10-20 Lilly Co Eli 20-amino-20-deoxo-5-o-mycaminosyl-23-o-mycinosyltylonolide derivatives,their preparation and veterinary antibiotic use
US4468511A (en) * 1983-02-28 1984-08-28 Eli Lilly And Company C-20- And C-23-Modified macrolide derivatives
IL71032A0 (en) 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
ZA841277B (en) * 1983-02-28 1985-09-25 Lilly Co Eli C-20-and c-23-modified macrolide derivatives
JPS59186996A (ja) * 1983-04-05 1984-10-23 Microbial Chem Res Found ２０−デオキシ−２０−置換アミノ−マイカミノシルレロノライド
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
EP0262903A3 (en) * 1986-09-29 1988-11-02 Eli Lilly And Company New acyl derivatives of 20-modified tylosin and desmycosin compounds
TW226373B (uk) * 1992-07-15 1994-07-11 Pfizer
CZ276893A3 (en) 1992-12-21 1994-07-13 Lilly Co Eli Pharmaceutical preparation for treating gramm-positive disease even of water animals
AU3121095A (en) 1994-09-22 1996-04-09 Pfizer Inc. Antibiotic macrolides
EP1216256B1 (en) * 1999-08-30 2004-03-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Macrolide antibiotics and treatment of pasteurellosis
US6506885B1 (en) * 2001-09-27 2003-01-14 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to the drug tilmicosin and a method for detecting the same
US6576615B2 (en) 2001-11-08 2003-06-10 Enanta Pharmaceuticals, Inc. 4′-O-substituted tylosin analogs
US6664240B2 (en) * 2001-11-15 2003-12-16 Enanta Pharmaceuticals, Inc. Tylosin derivatives having antibacterial activity
US6753415B2 (en) 2002-04-19 2004-06-22 Enanta Pharmaceuticals, Inc. 23-O-substituted 5-O-mycaminosyltylonide derivatives
US6710034B2 (en) 2002-04-19 2004-03-23 Enanta Pharmaceuticals, Inc. 5-O-mycaminosyltylonide derivatives
WO2005118610A2 (en) 2004-06-01 2005-12-15 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US7247617B2 (en) * 2004-07-13 2007-07-24 Kosan Biosciences Incorporated Sixteen-member macrolide antiinfective agents
US7282487B2 (en) * 2004-10-28 2007-10-16 Idexx Laboratories Method for treating bacterial infections in horses or pigs with tilmicosin
DE102005061326A1 (de) 2005-12-20 2007-06-21 Basell Polyolefine Gmbh Verfahren zur Herstellung von Metallocenen aus recycelten, substituierten Cyclopentadienylderivaten
CN101506220B (zh) * 2006-07-28 2012-10-17 英特威国际有限公司 大环内酯合成方法
KR101538599B1 (ko) * 2006-07-28 2015-07-21 인터벳 인터내셔널 비.브이. 마크롤라이드 합성 방법
EP2019112A1 (en) * 2007-07-26 2009-01-28 Intervet International BV Macrolide solid-state forms
US20090131343A1 (en) 2007-11-15 2009-05-21 Ly Tam Phan Use of bridged macrolides or tylosin derivatives in treating inflammatory bowel diseases
US20110071096A1 (en) * 2009-09-23 2011-03-24 Idexx Laboratories, Inc. Macrolides Having Antibiotic Activity
NO2782922T3 (uk) * 2011-11-25 2018-05-19

Also Published As

Publication number Publication date
NZ714071A (en) 2020-12-18
HUE037868T2 (hu) 2018-09-28
CA2913098A1 (en) 2014-11-27
NO2999707T3 (uk) 2018-08-25
US9771389B2 (en) 2017-09-26
EP2999707B1 (en) 2018-03-28
BR112015029260A2 (pt) 2017-07-25
DK2999707T3 (en) 2018-06-06
JP2016519153A (ja) 2016-06-30
CA2913098C (en) 2021-11-02
RU2015155032A3 (uk) 2018-04-28
RU2714482C2 (ru) 2020-02-18
AU2014270353B2 (en) 2018-09-20
AU2014270353A1 (en) 2015-11-26
RU2015155032A (ru) 2017-06-27
IL242543B (en) 2020-10-29
MX361808B (es) 2018-12-14
HK1216753A1 (zh) 2016-12-02
ES2669615T3 (es) 2018-05-28
CN105408340A (zh) 2016-03-16
HRP20180877T1 (hr) 2018-07-13
PE20160207A1 (es) 2016-05-22
EP2999707A1 (en) 2016-03-30
KR102307218B1 (ko) 2021-10-05
PL2999707T3 (pl) 2018-09-28
KR20160014656A (ko) 2016-02-11
MY184630A (en) 2021-04-11
US20160108077A1 (en) 2016-04-21
PT2999707T (pt) 2018-05-23
CL2015003433A1 (es) 2016-07-15
TR201809189T4 (tr) 2018-07-23
WO2014187957A1 (en) 2014-11-27
MX2015016118A (es) 2016-06-21
SI2999707T1 (en) 2018-07-31
CN105408340B (zh) 2020-06-12
JP6494600B2 (ja) 2019-04-03

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