MX361808B - Derivados de tilosina y metodo para su preparacion. - Google Patents

Derivados de tilosina y metodo para su preparacion.

Info

Publication number
MX361808B
MX361808B MX2015016118A MX2015016118A MX361808B MX 361808 B MX361808 B MX 361808B MX 2015016118 A MX2015016118 A MX 2015016118A MX 2015016118 A MX2015016118 A MX 2015016118A MX 361808 B MX361808 B MX 361808B
Authority
MX
Mexico
Prior art keywords
derivatives
preparation
animal
treating
tylosin derivatives
Prior art date
Application number
MX2015016118A
Other languages
English (en)
Other versions
MX2015016118A (es
Inventor
Froyman Robrecht
Omura Satoshi
Sunazuka Toshiaki
Kleefeld Gerd
Ludwig Carolin
Tomoyasu Hirose
Akihiro Sugawara
Kazuro Shiomi
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48463869&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX361808(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of MX2015016118A publication Critical patent/MX2015016118A/es
Publication of MX361808B publication Critical patent/MX361808B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invención se relaciona con nuevos derivados de macrólidos, en particular nuevos derivados de tilosina de la fórmula (IIa),(ver Fórmula) una composición farmacéutica o veterinaria que comprende los derivados; un método para su preparación; un método de tratamiento y/o prevención de infecciones bacterianas en un animal, que comprende administrar los derivados o la composición; y un uso de los derivados para la elaboración de medicamentos para el tratamiento y/o prevención de infecciones bacterianas en un animal.
MX2015016118A 2013-05-23 2014-05-23 Derivados de tilosina y metodo para su preparacion. MX361808B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13169009 2013-05-23
PCT/EP2014/060665 WO2014187957A1 (en) 2013-05-23 2014-05-23 Tylosin derivatives and method for preparation thereof

Publications (2)

Publication Number Publication Date
MX2015016118A MX2015016118A (es) 2016-06-21
MX361808B true MX361808B (es) 2018-12-14

Family

ID=48463869

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015016118A MX361808B (es) 2013-05-23 2014-05-23 Derivados de tilosina y metodo para su preparacion.

Country Status (26)

Country Link
US (1) US9771389B2 (es)
EP (1) EP2999707B1 (es)
JP (1) JP6494600B2 (es)
KR (1) KR102307218B1 (es)
CN (1) CN105408340B (es)
AU (1) AU2014270353B2 (es)
BR (1) BR112015029260A2 (es)
CA (1) CA2913098C (es)
CL (1) CL2015003433A1 (es)
DK (1) DK2999707T3 (es)
ES (1) ES2669615T3 (es)
HK (1) HK1216753A1 (es)
HR (1) HRP20180877T1 (es)
HU (1) HUE037868T2 (es)
IL (1) IL242543B (es)
MX (1) MX361808B (es)
MY (1) MY184630A (es)
NO (1) NO2999707T3 (es)
PE (1) PE20160207A1 (es)
PL (1) PL2999707T3 (es)
PT (1) PT2999707T (es)
RU (1) RU2714482C2 (es)
SI (1) SI2999707T1 (es)
TR (1) TR201809189T4 (es)
UA (1) UA117751C2 (es)
WO (1) WO2014187957A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
CN110590885A (zh) * 2019-09-30 2019-12-20 郑州大学 20-取代-5-o-碳霉胺糖基-泰乐内酯衍生物
CN112898361A (zh) * 2021-02-01 2021-06-04 郑州大学 5-o-碳霉胺糖基泰乐内酯衍生物及其制备方法及应用
WO2023230702A1 (en) * 2022-06-03 2023-12-07 University Of Manitoba Novel antimicrobial compounds isolated using a machine learning model trained on a high-throughput antibacterial screen

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
AU561147B2 (en) * 1982-09-13 1987-04-30 Eli Lilly And Company 20-amino macrolide antibiotics
ZA841277B (en) * 1983-02-28 1985-09-25 Lilly Co Eli C-20-and c-23-modified macrolide derivatives
US4468511A (en) * 1983-02-28 1984-08-28 Eli Lilly And Company C-20- And C-23-Modified macrolide derivatives
IL71032A0 (en) 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
JPS59186996A (ja) * 1983-04-05 1984-10-23 Microbial Chem Res Found ２０−デオキシ−２０−置換アミノ−マイカミノシルレロノライド
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
EP0262903A3 (en) * 1986-09-29 1988-11-02 Eli Lilly And Company New acyl derivatives of 20-modified tylosin and desmycosin compounds
TW226373B (es) * 1992-07-15 1994-07-11 Pfizer
NZ250465A (en) 1992-12-21 1995-10-26 Lilly Co Eli Bactericidal composition; contains macrolide antibiotic, use for treating aquatic species
AU3121095A (en) 1994-09-22 1996-04-09 Pfizer Inc. Antibiotic macrolides
PT1216256E (pt) * 1999-08-30 2004-07-30 Zaidan Hojin Biseibutsu Antibioticos macrolidos e tratamento de pasteurelose
US6506885B1 (en) * 2001-09-27 2003-01-14 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to the drug tilmicosin and a method for detecting the same
US6576615B2 (en) 2001-11-08 2003-06-10 Enanta Pharmaceuticals, Inc. 4′-O-substituted tylosin analogs
US6664240B2 (en) * 2001-11-15 2003-12-16 Enanta Pharmaceuticals, Inc. Tylosin derivatives having antibacterial activity
US6710034B2 (en) 2002-04-19 2004-03-23 Enanta Pharmaceuticals, Inc. 5-O-mycaminosyltylonide derivatives
US6753415B2 (en) 2002-04-19 2004-06-22 Enanta Pharmaceuticals, Inc. 23-O-substituted 5-O-mycaminosyltylonide derivatives
WO2005118610A2 (en) 2004-06-01 2005-12-15 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US7247617B2 (en) * 2004-07-13 2007-07-24 Kosan Biosciences Incorporated Sixteen-member macrolide antiinfective agents
US7282487B2 (en) * 2004-10-28 2007-10-16 Idexx Laboratories Method for treating bacterial infections in horses or pigs with tilmicosin
DE102005061326A1 (de) 2005-12-20 2007-06-21 Basell Polyolefine Gmbh Verfahren zur Herstellung von Metallocenen aus recycelten, substituierten Cyclopentadienylderivaten
EP2019112A1 (en) * 2007-07-26 2009-01-28 Intervet International BV Macrolide solid-state forms
PL2089408T3 (pl) * 2006-07-28 2012-03-30 Intervet Int Bv Sposób syntezy makrolidu
CN101506220B (zh) * 2006-07-28 2012-10-17 英特威国际有限公司 大环内酯合成方法
US20090131343A1 (en) 2007-11-15 2009-05-21 Ly Tam Phan Use of bridged macrolides or tylosin derivatives in treating inflammatory bowel diseases
US20110071096A1 (en) * 2009-09-23 2011-03-24 Idexx Laboratories, Inc. Macrolides Having Antibiotic Activity
CA2856708C (en) * 2011-11-25 2022-01-11 Bayer Intellectual Property Gmbh Antibacterial tylosin derivatives and methods for their preparation

Also Published As

Publication number Publication date
PT2999707T (pt) 2018-05-23
HRP20180877T1 (hr) 2018-07-13
CL2015003433A1 (es) 2016-07-15
RU2714482C2 (ru) 2020-02-18
JP2016519153A (ja) 2016-06-30
UA117751C2 (uk) 2018-09-25
ES2669615T3 (es) 2018-05-28
KR102307218B1 (ko) 2021-10-05
EP2999707A1 (en) 2016-03-30
DK2999707T3 (en) 2018-06-06
IL242543B (en) 2020-10-29
PL2999707T3 (pl) 2018-09-28
RU2015155032A3 (es) 2018-04-28
SI2999707T1 (en) 2018-07-31
HK1216753A1 (zh) 2016-12-02
CN105408340A (zh) 2016-03-16
US9771389B2 (en) 2017-09-26
CA2913098C (en) 2021-11-02
MY184630A (en) 2021-04-11
RU2015155032A (ru) 2017-06-27
TR201809189T4 (tr) 2018-07-23
CN105408340B (zh) 2020-06-12
AU2014270353B2 (en) 2018-09-20
AU2014270353A1 (en) 2015-11-26
WO2014187957A1 (en) 2014-11-27
PE20160207A1 (es) 2016-05-22
HUE037868T2 (hu) 2018-09-28
JP6494600B2 (ja) 2019-04-03
NZ714071A (en) 2020-12-18
US20160108077A1 (en) 2016-04-21
NO2999707T3 (es) 2018-08-25
EP2999707B1 (en) 2018-03-28
KR20160014656A (ko) 2016-02-11
MX2015016118A (es) 2016-06-21
BR112015029260A2 (pt) 2017-07-25
CA2913098A1 (en) 2014-11-27

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