UA105320C2 - Соединения дигидробензоксатиазепина, способ их получения и фармацевтическая композиция, которая их содержит - Google Patents

Соединения дигидробензоксатиазепина, способ их получения и фармацевтическая композиция, которая их содержит

Info

Publication number
UA105320C2
UA105320C2 UAA201304534A UAA201304534A UA105320C2 UA 105320 C2 UA105320 C2 UA 105320C2 UA A201304534 A UAA201304534 A UA A201304534A UA A201304534 A UAA201304534 A UA A201304534A UA 105320 C2 UA105320 C2 UA 105320C2
Authority
UA
Ukraine
Prior art keywords
compounds
dihydrobenzoxathiazepine
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
UAA201304534A
Other languages
English (en)
Ukrainian (uk)
Inventor
Алексіс Корді
Патріс Десос
Пьєр Лєстаж
Лоранс Данобер
Original Assignee
Ле Лаборатуар Сервьє
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43067253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA105320(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ле Лаборатуар Сервьє filed Critical Ле Лаборатуар Сервьє
Publication of UA105320C2 publication Critical patent/UA105320C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Соединения формулы (I): EMBED ISISServer (I), где R1 представляет собой атом водорода или гетероциклическую, циано, алкоксикарбонильную, алкилсульфониламиноалкильную или N-гидроксикарбоксимидамидную группу. Лекарственные средства.
UAA201304534A 2010-09-16 2011-09-15 Соединения дигидробензоксатиазепина, способ их получения и фармацевтическая композиция, которая их содержит UA105320C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1003683A FR2964969B1 (fr) 2010-09-16 2010-09-16 Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2011/000502 WO2012035216A1 (fr) 2010-09-16 2011-09-15 Derives dihydrobenzoxathiazepines, leur preparation, compositions pharmaceutiques et utilisation en tant que modulateurs des recepteurs ampa

Publications (1)

Publication Number Publication Date
UA105320C2 true UA105320C2 (ru) 2014-04-25

Family

ID=43067253

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201304534A UA105320C2 (ru) 2010-09-16 2011-09-15 Соединения дигидробензоксатиазепина, способ их получения и фармацевтическая композиция, которая их содержит

Country Status (40)

Country Link
US (1) US8569285B2 (ru)
EP (1) EP2431360B1 (ru)
JP (1) JP2013537216A (ru)
KR (1) KR20130054438A (ru)
CN (1) CN103153973A (ru)
AP (1) AP2013006793A0 (ru)
AR (1) AR082973A1 (ru)
AU (1) AU2011213898A1 (ru)
BR (1) BR112013005967A2 (ru)
CA (1) CA2752131C (ru)
CL (1) CL2013000655A1 (ru)
CO (1) CO6680709A2 (ru)
CR (1) CR20130105A (ru)
CU (1) CU20130037A7 (ru)
CY (1) CY1114110T1 (ru)
DK (1) DK2431360T3 (ru)
EA (1) EA201300340A1 (ru)
EC (1) ECSP13012489A (ru)
ES (1) ES2421504T3 (ru)
FR (1) FR2964969B1 (ru)
GE (1) GEP20156247B (ru)
GT (1) GT201300067A (ru)
HR (1) HRP20130505T1 (ru)
IL (1) IL225209A0 (ru)
MA (1) MA34529B1 (ru)
ME (1) ME01524B (ru)
MX (1) MX2013002892A (ru)
NI (1) NI201300028A (ru)
PE (1) PE20131342A1 (ru)
PL (1) PL2431360T3 (ru)
PT (1) PT2431360E (ru)
RS (1) RS52835B (ru)
SA (1) SA111320755B1 (ru)
SG (1) SG188380A1 (ru)
SI (1) SI2431360T1 (ru)
TW (1) TWI421080B (ru)
UA (1) UA105320C2 (ru)
UY (1) UY33574A (ru)
WO (1) WO2012035216A1 (ru)
ZA (1) ZA201106353B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111559990B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种小分子噁噻嗪类衍生物及其应用
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2214405C2 (ru) * 1998-02-18 2003-10-20 НьюроСёрч А/С Новые соединения и их применение в качестве положительных модуляторов амра-рецепторов
TWI232863B (en) * 2001-06-11 2005-05-21 Akzo Nobel Nv Benzoxazepine derivatives
MXPA03011562A (es) * 2001-06-14 2004-03-18 Akzo Nobel Nv Derivados de (pirido/tieno)-(f)-oxazepin-5-ona como moduladores positivos del receptor ampa.
FR2856064B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
HRP20130505T1 (hr) 2013-07-31
AP2013006793A0 (en) 2013-04-30
TW201212921A (en) 2012-04-01
ECSP13012489A (es) 2013-04-30
WO2012035216A1 (fr) 2012-03-22
BR112013005967A2 (pt) 2016-05-03
ME01524B (me) 2014-04-20
ES2421504T3 (es) 2013-09-03
CU20130037A7 (es) 2013-05-31
CR20130105A (es) 2013-05-16
NI201300028A (es) 2014-01-07
JP2013537216A (ja) 2013-09-30
ZA201106353B (en) 2012-05-30
CO6680709A2 (es) 2013-05-31
SI2431360T1 (sl) 2013-07-31
FR2964969A1 (fr) 2012-03-23
CA2752131A1 (fr) 2012-03-16
US20120071462A1 (en) 2012-03-22
SG188380A1 (en) 2013-04-30
CY1114110T1 (el) 2016-07-27
PL2431360T3 (pl) 2013-08-30
EP2431360B1 (fr) 2013-04-17
CN103153973A (zh) 2013-06-12
UY33574A (es) 2012-03-30
EA201300340A1 (ru) 2013-08-30
EP2431360A1 (fr) 2012-03-21
SA111320755B1 (ar) 2013-11-10
PE20131342A1 (es) 2013-11-28
GEP20156247B (en) 2015-02-10
CA2752131C (fr) 2014-04-22
KR20130054438A (ko) 2013-05-24
DK2431360T3 (da) 2013-07-22
AU2011213898A1 (en) 2012-04-05
IL225209A0 (en) 2013-06-27
PT2431360E (pt) 2013-05-14
FR2964969B1 (fr) 2012-08-24
RS52835B (en) 2013-10-31
GT201300067A (es) 2014-07-08
AR082973A1 (es) 2013-01-23
MX2013002892A (es) 2013-04-10
MA34529B1 (fr) 2013-09-02
CL2013000655A1 (es) 2013-08-09
US8569285B2 (en) 2013-10-29
TWI421080B (zh) 2014-01-01

Similar Documents

Publication Publication Date Title
AU2010246749A8 (en) Thiophene derivatives
GEP20135862B (en) Novel benzothiadiazepine compounds, method of their preparation, and pharmaceutical compositions containing thereof
MY160490A (en) Arylethynyl derivatives
MY193277A (en) Certain amino-pyrimidines, compositions thereof, and methods for their use
MX2011012198A (es) Aril-piridinas como inhibidoras de sintasa de aldosterona.
MX2010001754A (es) Derivados de azepina como inhibidores de gamma secretasa.
MX2014000626A (es) Nuevos derivados de indol sustituidos como moduladores de gamma secretasa.
GEP20146115B (en) Thieno [2,3-b] pyridine derivatives as viral replication inhibitors
MX2013012798A (es) Compuestos heterociclicos fusionados como moduladores del canal de sodio.
MX2011008864A (es) Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.
MX2009008264A (es) Compuestos espiro heterociclicos.
TN2012000152A1 (en) Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
MX347241B (es) Derivados de aminopirimidina para usarse como moduladores de la actividad de cinasa.
TN2012000248A1 (en) Novel spiropiperidine compounds
JO2673B1 (en) Diosmetin compounds, method of preparation and pharmaceutical compositions
EA201270428A1 (ru) Замещенные n-фенил-1-(4-пиридинил)-1н-пиразол-3-амины
MY152475A (en) Fused ring compounds and use thereof
IN2012DN01292A (ru)
TN2013000420A1 (en) 2-amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as vegf receptor kinase inhibitors
GEP20135997B (en) Tricyclic indazole compound, method of their preparation and pharmaceutical composition containing thereof
MX2009008221A (es) Antagonista de receptor de cromeno s1p1.
WO2011050054A3 (en) Coumarin compounds as receptor modulators with therapeutic utility
UA105320C2 (ru) Соединения дигидробензоксатиазепина, способ их получения и фармацевтическая композиция, которая их содержит
MX2012007253A (es) Derivados triciclicos y sus usos y composiciones farmaceuticas.
MX2011008126A (es) Compuestos de indol sustituidos como moduladores del receptor 1 de bradiquinina.