MX2013002892A - Derivados de dihidrobenzoxatiazepinas, preparacion de los mismos, composiciones farmaceuticas y uso como moduladores del receptor ampa. - Google Patents

Derivados de dihidrobenzoxatiazepinas, preparacion de los mismos, composiciones farmaceuticas y uso como moduladores del receptor ampa.

Info

Publication number
MX2013002892A
MX2013002892A MX2013002892A MX2013002892A MX2013002892A MX 2013002892 A MX2013002892 A MX 2013002892A MX 2013002892 A MX2013002892 A MX 2013002892A MX 2013002892 A MX2013002892 A MX 2013002892A MX 2013002892 A MX2013002892 A MX 2013002892A
Authority
MX
Mexico
Prior art keywords
receptor modulators
dihydrobenzoxathiazepine
derivatives
preparation
ampa receptor
Prior art date
Application number
MX2013002892A
Other languages
English (en)
Inventor
Pierre Lestage
Laurence Danober
Patrice Desos
Alexis Cordi
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43067253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013002892(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of MX2013002892A publication Critical patent/MX2013002892A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Compuesto de fórmula (I): (ver Fórmula) en la que R1 representa un átomo de hidrógeno, un grupo heterocíclico, ciano, alcoxicarbonilo, alquilsulfonilaminoalquilo o N-hidroxicarboximidamida; usos de los mismos como moduladores del receptor AMPA.
MX2013002892A 2010-09-16 2011-09-15 Derivados de dihidrobenzoxatiazepinas, preparacion de los mismos, composiciones farmaceuticas y uso como moduladores del receptor ampa. MX2013002892A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1003683A FR2964969B1 (fr) 2010-09-16 2010-09-16 Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2011/000502 WO2012035216A1 (fr) 2010-09-16 2011-09-15 Derives dihydrobenzoxathiazepines, leur preparation, compositions pharmaceutiques et utilisation en tant que modulateurs des recepteurs ampa

Publications (1)

Publication Number Publication Date
MX2013002892A true MX2013002892A (es) 2013-04-10

Family

ID=43067253

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002892A MX2013002892A (es) 2010-09-16 2011-09-15 Derivados de dihidrobenzoxatiazepinas, preparacion de los mismos, composiciones farmaceuticas y uso como moduladores del receptor ampa.

Country Status (40)

Country Link
US (1) US8569285B2 (es)
EP (1) EP2431360B1 (es)
JP (1) JP2013537216A (es)
KR (1) KR20130054438A (es)
CN (1) CN103153973A (es)
AP (1) AP2013006793A0 (es)
AR (1) AR082973A1 (es)
AU (1) AU2011213898A1 (es)
BR (1) BR112013005967A2 (es)
CA (1) CA2752131C (es)
CL (1) CL2013000655A1 (es)
CO (1) CO6680709A2 (es)
CR (1) CR20130105A (es)
CU (1) CU20130037A7 (es)
CY (1) CY1114110T1 (es)
DK (1) DK2431360T3 (es)
EA (1) EA201300340A1 (es)
EC (1) ECSP13012489A (es)
ES (1) ES2421504T3 (es)
FR (1) FR2964969B1 (es)
GE (1) GEP20156247B (es)
GT (1) GT201300067A (es)
HR (1) HRP20130505T1 (es)
IL (1) IL225209A0 (es)
MA (1) MA34529B1 (es)
ME (1) ME01524B (es)
MX (1) MX2013002892A (es)
NI (1) NI201300028A (es)
PE (1) PE20131342A1 (es)
PL (1) PL2431360T3 (es)
PT (1) PT2431360E (es)
RS (1) RS52835B (es)
SA (1) SA111320755B1 (es)
SG (1) SG188380A1 (es)
SI (1) SI2431360T1 (es)
TW (1) TWI421080B (es)
UA (1) UA105320C2 (es)
UY (1) UY33574A (es)
WO (1) WO2012035216A1 (es)
ZA (1) ZA201106353B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途
CN111559990B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种小分子噁噻嗪类衍生物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0101280A3 (en) * 1998-02-18 2003-02-28 Neurosearch As Positive ampa receptor modulator compounds and their use
TWI232863B (en) * 2001-06-11 2005-05-21 Akzo Nobel Nv Benzoxazepine derivatives
CN101029051B (zh) * 2001-06-14 2010-06-09 欧加农股份有限公司 作为AMPA受体正性调节剂的（噻吩并）-[f]-氧杂吖庚因-5-酮衍生物
FR2856064B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
US8569285B2 (en) 2013-10-29
SI2431360T1 (sl) 2013-07-31
ECSP13012489A (es) 2013-04-30
SG188380A1 (en) 2013-04-30
AR082973A1 (es) 2013-01-23
JP2013537216A (ja) 2013-09-30
CL2013000655A1 (es) 2013-08-09
AU2011213898A1 (en) 2012-04-05
EP2431360A1 (fr) 2012-03-21
TWI421080B (zh) 2014-01-01
AP2013006793A0 (en) 2013-04-30
FR2964969B1 (fr) 2012-08-24
IL225209A0 (en) 2013-06-27
TW201212921A (en) 2012-04-01
BR112013005967A2 (pt) 2016-05-03
HRP20130505T1 (hr) 2013-07-31
NI201300028A (es) 2014-01-07
CN103153973A (zh) 2013-06-12
PT2431360E (pt) 2013-05-14
CR20130105A (es) 2013-05-16
DK2431360T3 (da) 2013-07-22
EP2431360B1 (fr) 2013-04-17
ES2421504T3 (es) 2013-09-03
MA34529B1 (fr) 2013-09-02
PE20131342A1 (es) 2013-11-28
RS52835B (en) 2013-10-31
FR2964969A1 (fr) 2012-03-23
CO6680709A2 (es) 2013-05-31
GEP20156247B (en) 2015-02-10
SA111320755B1 (ar) 2013-11-10
EA201300340A1 (ru) 2013-08-30
ZA201106353B (en) 2012-05-30
ME01524B (me) 2014-04-20
GT201300067A (es) 2014-07-08
US20120071462A1 (en) 2012-03-22
CU20130037A7 (es) 2013-05-31
WO2012035216A1 (fr) 2012-03-22
KR20130054438A (ko) 2013-05-24
CA2752131C (fr) 2014-04-22
UY33574A (es) 2012-03-30
UA105320C2 (ru) 2014-04-25
PL2431360T3 (pl) 2013-08-30
CY1114110T1 (el) 2016-07-27
CA2752131A1 (fr) 2012-03-16

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