UA105201C2 - Застосування рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини для запобігання нейтропенії або лейкопенії - Google Patents

Застосування рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини для запобігання нейтропенії або лейкопенії

Info

Publication number
UA105201C2
UA105201C2 UAA201109961A UAA201109961A UA105201C2 UA 105201 C2 UA105201 C2 UA 105201C2 UA A201109961 A UAA201109961 A UA A201109961A UA A201109961 A UAA201109961 A UA A201109961A UA 105201 C2 UA105201 C2 UA 105201C2
Authority
UA
Ukraine
Prior art keywords
stimulating factor
colony stimulating
leukopenia
granulocyte colony
human
Prior art date
Application number
UAA201109961A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Джейсон Бенджамін Бок
Адам Карр Белл
Джеффрі Хепст
Original Assignee
Тева Фармасьютікал Індастріз Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тева Фармасьютікал Індастріз Лтд. filed Critical Тева Фармасьютікал Індастріз Лтд.
Publication of UA105201C2 publication Critical patent/UA105201C2/uk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UAA201109961A 2009-01-16 2010-01-15 Застосування рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини для запобігання нейтропенії або лейкопенії UA105201C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14544009P 2009-01-16 2009-01-16
US14543609P 2009-01-16 2009-01-16
PCT/US2010/021241 WO2010083439A2 (en) 2009-01-16 2010-01-15 Recombinant human albumin-human granulocyte colony stimulating factor for the prevention of neutropenia

Publications (1)

Publication Number Publication Date
UA105201C2 true UA105201C2 (uk) 2014-04-25

Family

ID=42260335

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA201109961A UA105201C2 (uk) 2009-01-16 2010-01-15 Застосування рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини для запобігання нейтропенії або лейкопенії
UAA201109963A UA103221C2 (uk) 2009-01-16 2010-01-15 Стабільний склад рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини

Family Applications After (1)

Application Number Title Priority Date Filing Date
UAA201109963A UA103221C2 (uk) 2009-01-16 2010-01-15 Стабільний склад рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини

Country Status (16)

Country Link
US (4) US20100227818A1 (enExample)
EP (2) EP2387419A2 (enExample)
JP (2) JP2012515222A (enExample)
KR (2) KR20110132327A (enExample)
CN (2) CN102395379B (enExample)
AU (2) AU2010204552B2 (enExample)
BR (2) BRPI1005159A2 (enExample)
CA (2) CA2749786A1 (enExample)
EA (2) EA201190079A1 (enExample)
IL (2) IL214052A0 (enExample)
MX (2) MX2011007582A (enExample)
NZ (2) NZ594056A (enExample)
SG (3) SG172941A1 (enExample)
UA (2) UA105201C2 (enExample)
WO (2) WO2010083439A2 (enExample)
ZA (1) ZA201105171B (enExample)

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Also Published As

Publication number Publication date
BRPI1004940A2 (pt) 2018-06-19
AU2010204552A1 (en) 2011-08-04
MX2011007583A (es) 2011-12-14
SG172941A1 (en) 2011-08-29
WO2010083434A2 (en) 2010-07-22
EA023344B1 (ru) 2016-05-31
IL214051A0 (en) 2011-08-31
CA2749802A1 (en) 2010-07-22
US20150202268A1 (en) 2015-07-23
US20100297062A1 (en) 2010-11-25
SG196821A1 (en) 2014-02-13
AU2010204547B2 (en) 2014-01-23
KR20110132326A (ko) 2011-12-07
CA2749786A1 (en) 2010-07-22
NZ594055A (en) 2013-03-28
JP5753095B2 (ja) 2015-07-22
IL214052A0 (en) 2011-08-31
EA201190080A1 (ru) 2014-03-31
JP2012515221A (ja) 2012-07-05
NZ594056A (en) 2013-03-28
AU2010204552B2 (en) 2014-05-01
KR20110132327A (ko) 2011-12-07
BRPI1005159A2 (pt) 2018-04-03
US20100227818A1 (en) 2010-09-09
WO2010083434A3 (en) 2010-09-10
US8323634B2 (en) 2012-12-04
WO2010083439A3 (en) 2010-09-10
MX2011007582A (es) 2011-12-14
ZA201105171B (en) 2015-12-23
US8993519B2 (en) 2015-03-31
EA201190079A1 (ru) 2013-02-28
US20130129669A1 (en) 2013-05-23
AU2010204547A1 (en) 2011-07-28
SG172940A1 (en) 2011-08-29
JP2012515222A (ja) 2012-07-05
CN102395379A (zh) 2012-03-28
CN102395379B (zh) 2015-07-22
CN102378635A (zh) 2012-03-14
EP2387419A2 (en) 2011-11-23
EP2387420A2 (en) 2011-11-23
WO2010083439A2 (en) 2010-07-22
CA2749802C (en) 2016-08-23
UA103221C2 (uk) 2013-09-25

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