UA104762C2 - Раствор для инъекции или инфузии ипаморелина диацетата - Google Patents

Раствор для инъекции или инфузии ипаморелина диацетата

Info

Publication number
UA104762C2
UA104762C2 UAA201200346A UAA201200346A UA104762C2 UA 104762 C2 UA104762 C2 UA 104762C2 UA A201200346 A UAA201200346 A UA A201200346A UA A201200346 A UAA201200346 A UA A201200346A UA 104762 C2 UA104762 C2 UA 104762C2
Authority
UA
Ukraine
Prior art keywords
ipamorelin
injection
infusion solutions
diacetate
acetic acid
Prior art date
Application number
UAA201200346A
Other languages
English (en)
Ukrainian (uk)
Inventor
Рубио Сильвина Гарсия
Даниел Бидлер
Хелле Вейбель
Риккардо Бралья
Original Assignee
ХЕЛСИНН ТЕРАПЬЮТИКС (Ю.Эс.), ИНК.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42272260&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA104762(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ХЕЛСИНН ТЕРАПЬЮТИКС (Ю.Эс.), ИНК. filed Critical ХЕЛСИНН ТЕРАПЬЮТИКС (Ю.Эс.), ИНК.
Publication of UA104762C2 publication Critical patent/UA104762C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Изобретение касается раствора для инъекции или инфузии ипаморелина, содержащего: а) ипаморелин, растворенный в двух молярных эквивалентах уксусной кислоты (ипаморелина диацетат) в количестве от 0,001 до 20 % в расчете на массу ипаморелина в виде свободного основания; b) молярный избыток кислоты, преимущественно уксусной кислоты, в количестве, достаточном для получения рН от как минимум 3 до менее 7; с) от 0,1 до 30 % одного или нескольких вспомогательных веществ; и d) воду в количестве, необходимом до 100%; все проценты приведены в расчете на общую массу раствора, где указанный раствор содержит от 1 до 10 молярных эквивалентов избытка уксусной кислоты.
UAA201200346A 2009-06-12 2010-05-27 Раствор для инъекции или инфузии ипаморелина диацетата UA104762C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18659509P 2009-06-12 2009-06-12
PCT/US2010/036365 WO2010144265A2 (en) 2009-06-12 2010-05-27 Ipamorelin diacetate injection and infusion solutions

Publications (1)

Publication Number Publication Date
UA104762C2 true UA104762C2 (ru) 2014-03-11

Family

ID=42272260

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201200346A UA104762C2 (ru) 2009-06-12 2010-05-27 Раствор для инъекции или инфузии ипаморелина диацетата

Country Status (24)

Country Link
US (1) US20100317581A1 (ru)
EP (1) EP2440180B1 (ru)
JP (1) JP2012529510A (ru)
KR (1) KR20120030530A (ru)
CN (1) CN102481251A (ru)
AU (1) AU2010259102B2 (ru)
BR (1) BRPI1012931A2 (ru)
CA (1) CA2765233A1 (ru)
CL (1) CL2011003131A1 (ru)
CO (1) CO6470880A2 (ru)
CR (1) CR20110618A (ru)
CU (1) CU20110232A7 (ru)
DO (1) DOP2011000383A (ru)
EA (1) EA201270011A1 (ru)
EC (1) ECSP11011516A (ru)
GT (1) GT201100318A (ru)
MX (1) MX2011013113A (ru)
NI (1) NI201100212A (ru)
NZ (1) NZ596641A (ru)
PE (1) PE20121064A1 (ru)
SG (1) SG176717A1 (ru)
TW (1) TW201106961A (ru)
UA (1) UA104762C2 (ru)
WO (1) WO2010144265A2 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6193017B2 (ja) * 2013-06-28 2017-09-06 テルモ株式会社 生体血管内血液置換用液体、生体血管内血液置換用液体製剤およびプレフィルドシリンジ
JP6562902B2 (ja) 2014-03-28 2019-08-21 テルモ株式会社 生体血管内血液置換用液体、生体血管内血液置換用液体製剤およびプレフィルドシリンジ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK281963B6 (sk) * 1993-12-23 2001-09-11 Novo Nordisk A/S Zlúčeniny ovplyvňujúce uvoľňovanie rastového hormónu, farmaceutické prostriedky s ich obsahom a ich použitie
JP2003501394A (ja) * 1999-06-04 2003-01-14 ノボ ノルディスク アクティーゼルスカブ 延長された重度の疾患の異化状態の処理のための組成物
CN101060856B (zh) * 2004-11-22 2011-01-19 诺和诺德公司 可溶、稳定的含胰岛素制剂
KR100700869B1 (ko) * 2005-06-03 2007-03-29 재단법인 목암생명공학연구소 Ｐｔｈ, 완충제 및 안정제를 포함하는 안정한 ｐｔｈ조성물
EP2129401B8 (en) * 2006-12-21 2020-01-15 Amgen Inc. Stable buffered formulations containing polypeptides
TWI429436B (zh) * 2007-04-10 2014-03-11 Helsinn Therapeutics Us Inc 使用生長激素促泌素治療或預防嘔吐之方法
JP2011507842A (ja) * 2007-12-21 2011-03-10 ヘルシン・セラピューティクス・ユーエス・インコーポレイテッド 消化器系の運動をイパモレリンを用いて刺激する方法
UA105657C2 (ru) * 2009-02-27 2014-06-10 Хелсінн Терапьютікс (Ю.Ес.), Інк. Улучшенные способы лечения мигрени на основе анаморелина

Also Published As

Publication number Publication date
TW201106961A (en) 2011-03-01
CL2011003131A1 (es) 2012-08-17
MX2011013113A (es) 2012-02-21
AU2010259102B2 (en) 2013-09-12
CA2765233A1 (en) 2010-12-16
GT201100318A (es) 2014-10-13
WO2010144265A2 (en) 2010-12-16
JP2012529510A (ja) 2012-11-22
NZ596641A (en) 2013-12-20
BRPI1012931A2 (pt) 2018-01-30
PE20121064A1 (es) 2012-09-03
EA201270011A1 (ru) 2012-05-30
CO6470880A2 (es) 2012-06-29
DOP2011000383A (es) 2012-05-31
AU2010259102A1 (en) 2012-01-12
NI201100212A (es) 2012-04-11
CU20110232A7 (es) 2012-06-21
CR20110618A (es) 2012-03-02
KR20120030530A (ko) 2012-03-28
CN102481251A (zh) 2012-05-30
ECSP11011516A (es) 2012-03-30
EP2440180A2 (en) 2012-04-18
EP2440180B1 (en) 2014-08-27
US20100317581A1 (en) 2010-12-16
WO2010144265A3 (en) 2011-11-24
SG176717A1 (en) 2012-01-30

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