UA102587C2 - Применение композиции для лечения тяжелой и неконтролируемой астмы - Google Patents

Применение композиции для лечения тяжелой и неконтролируемой астмы

Info

Publication number
UA102587C2
UA102587C2 UAA201110621A UAA201110621A UA102587C2 UA 102587 C2 UA102587 C2 UA 102587C2 UA A201110621 A UAA201110621 A UA A201110621A UA A201110621 A UAA201110621 A UA A201110621A UA 102587 C2 UA102587 C2 UA 102587C2
Authority
UA
Ukraine
Prior art keywords
severe
treatment
uncontrolled asthma
glucocorticoid composition
corticosteroid
Prior art date
Application number
UAA201110621A
Other languages
English (en)
Ukrainian (uk)
Inventor
Бернхард МЮЛЛИНГЕР
Герхард ШОЙХ
Томас ХОФМАНН
Филипп КРОНЕБЕРГ
Original Assignee
Активаэро Гмбх Рисерч Энд Дивелопмент
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42153807&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA102587(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Активаэро Гмбх Рисерч Энд Дивелопмент filed Critical Активаэро Гмбх Рисерч Энд Дивелопмент
Publication of UA102587C2 publication Critical patent/UA102587C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение касается лечения тяжелой и неконтролируемой астмы с применением вдыхаемой композиции глюкокортикоида в виде распыленного аэрозоля, который генерируется ингаляционным устройством, с помощью которого большие количества вдыхаемого глюкокортикоида направляются к нижним дыхательным путям нижних отделов легких. Изобретение обеспечивает существенное уменьшение дозы пероральных глюкокортикоидов, которые вводят одновременно.
UAA201110621A 2009-02-04 2010-02-03 Применение композиции для лечения тяжелой и неконтролируемой астмы UA102587C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/365,754 US20100196483A1 (en) 2009-02-04 2009-02-04 Method for treatmentof severe and uncontrollable asthma
PCT/EP2010/051321 WO2010089330A1 (en) 2009-02-04 2010-02-03 Use of a glucocorticoid composition for the treatment of severe and uncontrolled asthma

Publications (1)

Publication Number Publication Date
UA102587C2 true UA102587C2 (ru) 2013-07-25

Family

ID=42153807

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201110621A UA102587C2 (ru) 2009-02-04 2010-02-03 Применение композиции для лечения тяжелой и неконтролируемой астмы

Country Status (22)

Country Link
US (1) US20100196483A1 (ru)
EP (2) EP2393477B1 (ru)
JP (1) JP5886630B2 (ru)
KR (1) KR20110122671A (ru)
CN (2) CN104306360A (ru)
AU (1) AU2010210183B2 (ru)
BR (1) BRPI1008227A8 (ru)
CA (1) CA2751443C (ru)
DK (1) DK2393477T3 (ru)
ES (1) ES2659328T3 (ru)
HU (1) HUE038553T2 (ru)
IL (1) IL213959A (ru)
MX (1) MX2011008200A (ru)
NO (1) NO2393477T3 (ru)
NZ (1) NZ594210A (ru)
PL (1) PL2393477T3 (ru)
PT (1) PT2393477T (ru)
RU (1) RU2519344C2 (ru)
SG (1) SG173538A1 (ru)
SI (1) SI2393477T1 (ru)
UA (1) UA102587C2 (ru)
WO (1) WO2010089330A1 (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2230934B8 (en) 2007-12-14 2012-10-24 AeroDesigns, Inc Delivering aerosolizable food products
KR101903028B1 (ko) 2012-03-09 2018-10-02 벡투라 게엠베하 흡입 장치용 혼합 채널 및 흡입 장치
WO2014012954A1 (en) * 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
US20140261474A1 (en) * 2013-03-15 2014-09-18 Aradigm Corporation Methods for inhalation of smoke-free nicotine
WO2014204511A2 (en) 2013-06-18 2014-12-24 Isonea Limited Compliance monitoring for asthma inhalers
JP6529012B2 (ja) 2013-10-08 2019-06-12 エイアイ・セラピューティクス・インコーポレーテッド リンパ脈管筋腫症の処置のためのラパマイシン
US20160339010A1 (en) * 2014-01-22 2016-11-24 Takeda Gmbh Treatment of Partly Controlled or Uncontrolled Severe Asthma
CA2944075C (en) 2014-04-04 2022-06-28 Lam Therapeutics, Inc. An inhalable rapamycin formulation for treating age-related conditions
MX2016017038A (es) * 2014-06-25 2017-05-01 Optinose As Administracion nasal.
RU2732908C2 (ru) 2014-10-07 2020-09-24 ЭйАй ТЕРАПЬЮТИКС, ИНК. Ингаляционная лекарственная форма рапамицина для лечения легочной гипертензии
RU2611406C1 (ru) * 2015-09-03 2017-02-21 Общество с ограниченной ответственностью "Биосурф" (ООО "Биосурф") Способ лечения бронхиальной астмы
CA3028604C (en) 2016-07-08 2023-12-05 Trudell Medical International Smart oscillating positive expiratory pressure device
MX2019006702A (es) 2016-12-09 2019-08-01 Trudell Medical Int Nebulizador inteligente.
JP7312754B2 (ja) 2018-01-04 2023-07-21 トゥルーデル メディカル インターナショナル スマート振動型呼気陽圧器具
WO2021038467A1 (en) 2019-08-27 2021-03-04 Trudell Medical International Smart oscillating positive expiratory pressure device
US11593679B2 (en) * 2019-11-29 2023-02-28 Kpn Innovations, Llc. Method of and system for generating a longevity element and an instruction set for a longevity element plan
US20220246260A1 (en) * 2021-01-29 2022-08-04 AsthmaTek, Inc. Systems and methods to determine a therapy regimen to treat asthma of a subject

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19720701A1 (de) * 1997-05-16 1998-11-19 Gsf Forschungszentrum Umwelt Vorrichtung zur Applikation eines Medikament-Aerosols über die Lunge
US6187765B1 (en) * 1997-10-09 2001-02-13 Schering Corporation Mometasone furoate suspensions for nebulization
DE19851279B4 (de) * 1998-06-17 2006-05-24 GSF - Forschungszentrum für Umwelt und Gesundheit GmbH Vorrichtung zum gesteuerten inhalatorischen Einbringen von dosierten Medikamenten in die Lunge
DE19912265A1 (de) * 1999-03-18 2000-09-21 Gsf Forschungszentrum Umwelt Verfahren und Vorrichtung zur Bereitstellung einer konstanten Medikamenten-Dosis für eine inhalatorische Applikation mit niedrigem Inhalationsfluß
DE19912461B4 (de) * 1999-03-19 2006-07-20 GSF - Forschungszentrum für Umwelt und Gesundheit GmbH Vorrichtung zur Flußbegrenzung bei niedrigen Differenzdrücken
DE10013093B4 (de) * 2000-03-17 2005-12-22 Inamed Gmbh Vorrichtung zur kontrollierten Inhalation therapeutischer Aerosole
DE10029119B4 (de) * 2000-06-14 2005-12-22 Institut für Aerosol Medizin InAMed GmbH Inhalationsvorrichtung
DE10123749A1 (de) * 2001-05-16 2002-12-12 Inamed Gmbh Vorrichtung zum Verabreichen von Aerosolen
NZ548225A (en) * 2003-12-31 2012-12-21 Cydex Pharmaceuticals Inc Inhalant formulation containing sulfoakyl ether cyclodextrin and corticosteroid
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
EP1700614B1 (de) * 2005-03-08 2013-05-08 Activaero GmbH Inhalationsvorrichtung
ES2290827T3 (es) * 2005-07-06 2008-02-16 Activaero Gmbh Valvula regulable y dispositivo para inhalar.
KR100802292B1 (ko) * 2006-07-21 2008-02-11 동부일렉트로닉스 주식회사 마스크 및 이를 이용한 마이크로 렌즈 제작 방법
PT2173169E (pt) * 2007-06-28 2014-09-03 Cydex Pharmaceuticals Inc Entrega nasal de soluções de corticosteróide aquosas
JP2012505262A (ja) * 2008-10-14 2012-03-01 アクティファエロ ゲーエムベーハー Copd及びその他の肺疾患の治療方法

Also Published As

Publication number Publication date
EP2393477A1 (en) 2011-12-14
CA2751443C (en) 2018-03-20
CN102307567A (zh) 2012-01-04
HUE038553T2 (hu) 2018-10-29
IL213959A (en) 2015-05-31
BRPI1008227A8 (pt) 2018-12-11
AU2010210183A1 (en) 2011-07-28
IL213959A0 (en) 2011-08-31
SG173538A1 (en) 2011-09-29
MX2011008200A (es) 2011-10-21
PL2393477T3 (pl) 2018-06-29
ES2659328T3 (es) 2018-03-14
NO2393477T3 (ru) 2018-05-26
PT2393477T (pt) 2018-02-14
AU2010210183B2 (en) 2014-09-11
JP5886630B2 (ja) 2016-03-16
CA2751443A1 (en) 2010-08-12
SI2393477T1 (en) 2018-04-30
WO2010089330A1 (en) 2010-08-12
NZ594210A (en) 2013-09-27
RU2519344C2 (ru) 2014-06-10
KR20110122671A (ko) 2011-11-10
DK2393477T3 (en) 2018-04-09
EP3338782A1 (en) 2018-06-27
EP2393477B1 (en) 2017-12-27
RU2011135824A (ru) 2013-03-10
BRPI1008227A2 (pt) 2016-03-08
US20100196483A1 (en) 2010-08-05
CN104306360A (zh) 2015-01-28
JP2012516873A (ja) 2012-07-26

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