UA101192C2 - Спосіб лікування раку молочної залози - Google Patents

Спосіб лікування раку молочної залози Download PDF

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Publication number
UA101192C2
UA101192C2 UAA201014040A UAA201014040A UA101192C2 UA 101192 C2 UA101192 C2 UA 101192C2 UA A201014040 A UAA201014040 A UA A201014040A UA A201014040 A UAA201014040 A UA A201014040A UA 101192 C2 UA101192 C2 UA 101192C2
Authority
UA
Ukraine
Prior art keywords
progesterone
treatment
tumors
compositions
sov
Prior art date
Application number
UAA201014040A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Джозеф С. Подольски
Роналд Д. Виле
Original Assignee
Репрос Терапьютикс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40758440&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA101192(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Репрос Терапьютикс Инк. filed Critical Репрос Терапьютикс Инк.
Publication of UA101192C2 publication Critical patent/UA101192C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UAA201014040A 2008-04-28 2009-04-27 Спосіб лікування раку молочної залози UA101192C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4845208P 2008-04-28 2008-04-28
PCT/US2009/041836 WO2009134723A1 (en) 2008-04-28 2009-04-27 Pregesteron antagonists such as cdb-4124 in the treatment of breast cancer

Publications (1)

Publication Number Publication Date
UA101192C2 true UA101192C2 (uk) 2013-03-11

Family

ID=40758440

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201014040A UA101192C2 (uk) 2008-04-28 2009-04-27 Спосіб лікування раку молочної залози

Country Status (21)

Country Link
US (2) US20110053900A1 (enExample)
EP (2) EP2293798A1 (enExample)
JP (1) JP5576362B2 (enExample)
KR (1) KR101349737B1 (enExample)
CN (1) CN102099040B (enExample)
AR (1) AR071419A1 (enExample)
AU (1) AU2009241360B2 (enExample)
BR (1) BRPI0911112A2 (enExample)
CA (1) CA2722637C (enExample)
CL (1) CL2009001011A1 (enExample)
EA (1) EA019224B1 (enExample)
IL (2) IL208845A (enExample)
ME (1) ME01122B (enExample)
MX (1) MX2010011273A (enExample)
MY (1) MY161549A (enExample)
NI (1) NI201000184A (enExample)
NZ (1) NZ589534A (enExample)
TW (1) TWI539953B (enExample)
UA (1) UA101192C2 (enExample)
WO (1) WO2009134723A1 (enExample)
ZA (1) ZA201007648B (enExample)

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US20130272956A1 (en) 2010-06-17 2013-10-17 Franciscus Theodorus Leonardus Brands (11beta, 17alpha)-11-(4-(2-11C-ACETYL)PHENYL)-17,23-EPOXY-19,24-DINORCHOLA-4,9,20-TRIEN-3-ONE
UA113283C2 (xx) * 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
MX369028B (es) 2011-10-04 2019-10-25 Invivis Pharmaceuticals Inc Anti-progestinas para ser usadas en un metodo para inhibir el crecimiento de un tumor susceptible a inhibición del crecimiento por anti-progestinas.
FR2997628B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone
AU2014228990B2 (en) * 2013-03-15 2017-02-02 Aprecia Pharmaceuticals LLC Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
HU230381B1 (hu) * 2014-02-17 2016-03-29 Richter Gedeon Nyrt Ipari eljárás szteroid intermedier előállítására
JP6655075B2 (ja) 2014-11-17 2020-02-26 コンテクスト バイオファーマ インコーポレイテッド オナプリストン持続放出組成物および方法
BR112018005999A2 (pt) 2015-09-25 2019-01-08 Context Biopharma Inc métodos para a produção de intermediários de onapristona
CA3008422A1 (en) 2015-12-15 2017-06-22 Context Biopharma Inc. Amorphous onapristone compositions and methods of making the same
IL261957B (en) 2016-03-28 2022-07-01 Incyte Corp Pyrrolotriazine compounds as TAM inhibitors
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2018106914A1 (en) * 2016-12-09 2018-06-14 Repros Therapeutics Inc. Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent
JOP20200081A1 (ar) 2017-09-27 2020-04-30 Incyte Corp أملاح من مشتقات بيرولوتريازين مفيدة بوصفها مثبطات لـ tam
DK3813800T3 (da) 2018-06-29 2025-06-02 Incyte Corp Formuleringer af en axl/mer-hæmmer
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ
WO2021178779A1 (en) 2020-03-06 2021-09-10 Incyte Corporation Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors

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Also Published As

Publication number Publication date
NI201000184A (es) 2011-08-10
US20140343022A1 (en) 2014-11-20
JP2011518883A (ja) 2011-06-30
ZA201007648B (en) 2011-07-27
ME01122B (me) 2013-03-20
CN102099040A (zh) 2011-06-15
CN102099040B (zh) 2013-06-19
IL208845A0 (en) 2011-01-31
CA2722637C (en) 2015-03-10
WO2009134723A9 (en) 2010-01-21
US20110053900A1 (en) 2011-03-03
KR101349737B1 (ko) 2014-02-07
HK1155084A1 (en) 2012-05-11
TW201002330A (en) 2010-01-16
MY161549A (en) 2017-04-28
IL247093A0 (en) 2016-09-29
EP2293798A1 (en) 2011-03-16
IL208845A (en) 2016-08-31
NZ589534A (en) 2012-08-31
WO2009134723A1 (en) 2009-11-05
JP5576362B2 (ja) 2014-08-20
KR20110003553A (ko) 2011-01-12
EP2974772A1 (en) 2016-01-20
AU2009241360B2 (en) 2012-03-08
MX2010011273A (es) 2010-12-21
TWI539953B (zh) 2016-07-01
AU2009241360A1 (en) 2009-11-05
CL2009001011A1 (es) 2009-09-25
EA019224B1 (ru) 2014-02-28
BRPI0911112A2 (pt) 2015-10-06
EA201071250A1 (ru) 2011-04-29
AR071419A1 (es) 2010-06-16
CA2722637A1 (en) 2009-11-05

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