TWM591889U - Centrifugal tube - Google Patents

Abstract

This creative department provides a centrifuge tube, which includes: a bottle body having an accommodating space formed by a bottom surface and a bottle wall, the lower part of the accommodating space is in the shape of a round table, the bottle body has an upper opening, and the upper opening is to The distance of the bottom surface is the height; the upper cover connected to the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening to seal the upper opening with the upper cover; and the suction tube including the first end and the second end, The first end is connected to and penetrates the upper cover, and the second end extends in the accommodating space; wherein the second end extends to a position of 0~5mm from the bottom surface.

Description

Centrifuge tube

This creation relates to a centrifuge tube, in particular, a centrifuge tube with a suction tube that can easily obtain centrifugal fluid.

Since the centrifugation step can effectively separate different substances with different settling rates and densities in the mixture, the centrifugation step is widely used in chemical engineering, petroleum, food processing and other fields. Among them, the centrifuge tube is often used to contain the liquid to be centrifuged, and a centrifuge is used to facilitate the centrifugation step.

At present, the components of commercially available centrifuge tubes can be mainly divided into an upper cap and a bottle body. The upper cover mainly uses a sealed bottle body to prevent the liquid contained in the centrifuge tube from leaking, and at the same time provides the support force of the bottle body to avoid damage to the bottle body during the centrifugation step. The bottle body can be classified into plastic, glass and stainless steel according to the material, and can also be divided into flat bottom, round bottom or conical bottom according to the shape of the bottom, but no matter what type of bottle is selected, it is mainly used to match the type of liquid to be centrifuged and Centrifugal speed.

However, for those of ordinary skill in the art, after centrifugation using a commercially available centrifuge tube containing the liquid to be centrifuged, if the centrifuged liquid has an interface, that is, the centrifuged liquid is divided into at least two layers It can only be obtained by using a pipette to draw the upper layer liquid first and then the lower layer liquid; or directly using a pipette to extract the lower layer liquid through the interface. However, this method can easily damage the interface after centrifugation, and greatly reduce the separation effect.

In view of the above-mentioned problems of the conventional technology, the present invention provides a centrifuge tube, which is provided with a suction tube at the upper opening, so that the user can easily obtain the centrifuged liquid.

According to the purpose of this creation, a centrifuge tube includes: a bottle body having an accommodating space formed by a bottom surface and a bottle wall, a lower portion of the accommodating space is in the shape of a rounded table, and the bottle body has an upper opening, And the distance from the upper opening to the bottom surface is the height; the upper cover connected to the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening to seal the upper opening by the upper cover; and includes the first end and the second At the end of the suction tube, the first end is connected and penetrates the upper cover, and the second end extends into the accommodating space; wherein the second end extends to a position of 0~5mm from the bottom surface.

Optionally, the suction tube moves up and down along the height direction.

Optionally, when the second end moves up to the limit position along the height direction, the second end extends to a position 10 to 15 mm from the bottom surface; and when the second end moves down to the limit position along the height direction, the first The two ends extend to a position of 0~3mm from the bottom surface.

Optionally, the centrifuge tube further includes: an auxiliary suction tube including a third end and a fourth end, the third end is connected to and penetrates the upper cover, and the fourth end extends in the accommodating space, and compared to the suction tube, the auxiliary The pipette is closer to the bottle wall.

Optionally, the fourth end extends to a position 10 to 15 mm from the bottom surface.

Optionally, the suction tube further includes: an inner tube having an upper opening of the inner tube and a lower opening of the inner tube, and the upper opening of the inner tube is closer to the upper opening than the lower opening of the inner tube; and sleeved outside the inner tube, The outer tube has an upper opening of the outer tube and a lower opening of the outer tube, and the upper opening of the outer tube is closer to the upper opening than the lower opening of the outer tube; wherein the center of the upper opening of the inner tube and the center of the lower opening of the inner tube are along The height direction is a straight line, and the center of the upper opening of the outer tube and the center of the lower opening of the outer tube are not straight along the height direction; or the center of the upper opening of the outer tube and the center of the lower opening of the outer tube are along the height direction The upper part is a straight line, and the center of the upper opening of the inner tube and the center of the lower opening of the inner tube are not straight lines along the height direction.

According to another object of this creation, a centrifuge tube is provided, which comprises: a hollow cylindrical body with an upper opening and a lower opening; an upper cover connected to the upper portion of the bottle, and an inner diameter of the lower end surface of the upper cover Corresponding to the outer diameter of the upper opening to seal the upper opening with the upper lid; and a soft plug connected to the lower part of the bottle body and having a plurality of soft plug sealing rings on the outer peripheral surface of the soft plug, and the upper side of the soft plug The outer diameter of the end face corresponds to the inner diameter of the lower opening to seal the lower opening with a soft plug; wherein, the soft plug is an elastic body for puncturing a hole.

Optionally, the centrifuge tube further includes: a lower cover connected to the lower part of the bottle body and having a plurality of lower cover sealing rings located on the upper portion of the lower cover, and the lower cover is in the shape of a rounded table, and the lower The outer diameter of the upper end face of the cap is larger than the outer diameter of the lower end face of the lower cap, and the outer diameter of the upper end face of the lower cap corresponds to the inner diameter of the bottle body.

Optionally, the centrifuge tube further includes: a bottle body fixing frame having an accommodating space for accommodating the bottle body, and the bottle body fixing frame has an upper end inner diameter and a lower end inner diameter, and the upper end inner diameter is smaller than the lower end inner The inner diameter of the bottle holder is gradually increased from the inner diameter of the upper end to the inner diameter of the lower end, and the outer diameter of the bottle is between the inner diameter of the upper end and the inner diameter of the lower end; and the bottle holder is connected and has a concave In the base of the groove, the outer diameter of the groove corresponds to the outer diameter of the lower end of the bottle body fixing frame, so that the bottle body fixing frame is fixed on the base through the groove.

Optionally, the centrifuge tube further includes: an outlet fixing frame provided in the bottle fixing frame and including a through hole, and the outer diameter of the outlet fixing frame is between the inner diameter of the upper end of the bottle fixing frame and Between the inner diameter of the lower end.

Optionally, the centrifuge tube further includes: an outlet member connected to the outlet member holder, and the outlet member includes: a needle including a first needle end and a second needle end, the first needle end extending into the interior of the bottle, and The second needle end extends to the through hole to allow the needle to pierce the soft plug through the through hole; it is a hollow cylindrical shape and includes an extension tube with a first extension end and a second extension end, and the first extension end is connected to the second needle of the needle And the collection bottle connected to the second extension end of the extension tube; wherein the bottle body, the needle, the extension tube and the collection bottle are spatially connected.

Optionally, the centrifuge tube further includes: an injection hole provided on the upper cover and penetrating the upper cover; an air hole provided on the upper cover and penetrating the upper cover; and a first convex portion connected to the upper cover and including a corresponding injection hole And a sealing cover corresponding to the second convex portion of the air hole, so that the sealing cover seals the injection hole and the air hole; wherein the inner diameter of the injection hole is larger than the inner diameter of the air hole.

The centrifuge tube of this creation has the following advantages:

(1) In an embodiment, since the centrifuge tube of the present invention has a suction tube connected to the upper cover, since the suction tube has been extended into the accommodating space before centrifugation using the centrifuge tube, it can be directly suctioned after centrifugation The centrifuged liquid is led out of the hollow diameter of the tube to achieve the purpose of direct stratification.

(2) In one embodiment, since the suction tube of the centrifuge tube of the present invention can move up and down along the height direction, the position of the suction tube can be adjusted according to the position of the layered position of the centrifuged liquid to achieve the adjustment The purpose of the components of the liquid to be absorbed.

(3) In an embodiment, since the centrifuge tube of the present invention includes a suction tube, it further includes an auxiliary suction tube, so the centrifuged liquid can be drawn from the suction tube and the auxiliary suction tube in a specific order. , And with repeated centrifugation steps, can further adjust the composition of the liquid to be sucked.

(4) In an embodiment, since the suction tube of the centrifuge tube of the present invention has an inner tube and an outer tube that can rotate with each other, and the inner tube and the outer tube have corresponding upper and lower openings, they can be rotated by To a specific position, adjust the position of the suction pipe to suck, and achieve the purpose of adjusting the composition of the liquid to be sucked.

(5) In one embodiment, since the centrifuge tube of the present invention has a soft stopper, when the liquid contained in the bottle body of the centrifuge tube is centrifuged and layered, the user can use an outlet such as a needle Puncturing the soft plug allows the liquid fluid sealed by the soft plug to circulate to the outlet member and then collect it, so as to achieve effective collection and avoid the remixing of the layered liquid without damaging the centrifugal interface.

(6) In one embodiment, since the centrifuge tube of the present invention has a fixing frame for the lead-out part, the fixed point of the commercially available needle has a standard size with its outer diameter and length as the standard, and it is fixed by adjusting the lead-out part The height and diameter of the through hole of the rack control the depth of the needle inserted into the soft stopper from the bottom to the top through the fixing frame of the outlet member, so as to achieve the purpose of standardized selection of the type of layered liquid to be drawn. For example, if the liquid contained in the bottle is centrifugally divided into three layers: upper, middle, and lower, the layer to be drawn can be selected according to the size of the needle and the outlet holder.

(7) In one embodiment, since the centrifuge tube of the present invention has an extension tube with a thinner diameter and can be made of transparent plastic material, when exporting the centrifuged liquid, the layered interface can be observed more accurately Where it is, so as to achieve the purpose of finer layering.

(8) In an embodiment, since the centrifuge tube of the present invention has a bottle holder and a base, the centrifuge tube can be stabilized by using different weights to achieve the purpose of convenient access.

In order to better understand the technical features, content and advantages of this creation and the achievable effects, the creation is combined with the drawings, and the expressions of the embodiments are described in detail below. The purpose of the drawings used is only For the purpose of illustration and supplementary instruction, it may not be the true proportion and precise configuration after the implementation of the creation, so the ratio and configuration relationship of the attached drawings should not be interpreted and limited to the scope of patent application for the actual implementation of the creation. First clarify. And for ease of understanding, the same elements in the following embodiments are described with the same symbols.

In the description of this creation, it should be noted that, unless otherwise clearly specified and limited, the terms "connection" and "setting" should be broadly understood, for example, it can be a fixed connection or a detachable connection, or Integrally connected; it can be directly connected or indirectly connected through an intermediary, or it can be the connection between two components. For those of ordinary knowledge in the technical field to which they belong, they can understand the specific meaning of the above terms in this creation in specific circumstances.

Refer to FIG. 1, which is a schematic structural view of the first embodiment of the centrifuge tube of the present invention.

As shown in FIG. 1, the centrifuge tube 1 includes a bottle body 300, an upper cap 200, and a suction tube 203a.

The bottle body 300 may have an accommodating space formed by the bottom surface 300a and the bottle wall 300b, and the accommodating space is used to accommodate the liquid to be centrifuged, the suspended liquid, the colloid, and the like. The bottle body 300 is hollow, and the bottle body 300 may have a desired shape such as a hollow cylinder or a hollow polygon. The bottle body 300 can be made of plastic, stainless steel, glass and other materials. The lower part of the accommodating space can be in the shape of a round table, so the centrifuge tube 1 can match the shape of the rotor of a commercially available centrifuge. Therefore, the centrifuge tube 1 of this creation can be used for centrifugation without changing the design of the commercially available centrifuge. The accommodating space of the bottle body 300 may have an upper opening 301. The area and shape of the upper opening 301 can be modified according to the type of liquid contained. The distance from the upper opening 301 to the bottom surface 300a may be a height H. In one embodiment, the height H of the bottle body 300 is preferably 110-120 mm; more preferably 112-128 mm; and still more preferably 114-116 mm, which is beneficial to general-purpose commercial centrifuges and fixed centrifugal conditions.

The upper cover 200 may be connected to the upper part of the bottle body 300. The upper cover 200 may be screwed onto the bottle body 300 or may be directly fastened to the bottle body 300. The inner diameter of the lower end surface of the upper cover 200 may correspond to the outer diameter of the upper opening 301. For example, the inner diameter of the lower end surface of the upper cover 200 may be slightly smaller than, equal to, or slightly larger than the outer diameter of the upper opening 301. Seal the upper opening 301. The suction tube 203a may include a suction tube with a first end 203a1 and a second end 203a2. The first end 203a1 may be connected and penetrate the upper cover 200. The second end 203a2 can extend into the accommodating space, so the centrifuge tube 1 can directly suck the centrifuged lower layer liquid through the suction tube 203a. In one embodiment, preferably, the second end 203a2 extends to a position of 0~5mm from the bottom surface 300a; more preferably a position of 0~3mm; and still more preferably a position of 0.5~1mm, so as to be controlled by The length of the suction pipe 203a is controlled uniformly to control the composition of the liquid to be centrifuged.

In an embodiment, the suction tube 203a may be disposed at the center of the upper cover 200. However, in another embodiment, the suction tube 203a may be disposed near the edge of the upper cover 200. For example, the suction tube 203a may be preferably disposed 8 to 20 mm from the edge of the upper cover 200; preferably 10 to 17 mm; and more preferably 13 to 15 mm, so as to facilitate the closest to the bottom surface Draw.

Refer to FIG. 2, which is a side view of the upper cover of the first embodiment of the centrifuge tube of the present invention.

As shown in FIG. 2, the upper cover 200 of the centrifuge tube 1 includes an injection hole 201 and an air hole 202. The injection hole 201 can be provided on the upper cover 200 and can penetrate the upper cover 200 for injecting the liquid to be centrifuged into the bottle body 300. The air hole 202 may be provided in the upper cover 200 and may penetrate the upper cover 200 to facilitate exhaust. The inner diameter of the injection hole 201 may be larger than the inner diameter of the gas hole 202, so that the liquid to be centrifuged is not affected by the original air pressure in the centrifuge tube 1 when it is injected. In addition, the centrifuge tube 1 may include a sealing cap for sealing the injection hole 201 and/or the air hole 202. The sealing cover is detachably sealed.

Refer to FIG. 3, which is a schematic structural view of the suction tube of the first embodiment of the centrifuge tube of the present invention. Parts (A) and (B) of FIG. 3 are structural schematic diagrams of the separation and combination of the spiral structure 206 and the upper cover 200. As shown in FIG. 3, the suction tube of the centrifuge tube 1 is moved up and down by the spiral structure 206. When the second end 203a2 of the suction tube 203a moves upward to the limit position along the direction of the height H, preferably, the second end 203a2 extends to a position of 8~20mm from the bottom surface 300a, more preferably 10~17mm The position is more preferably 13~15mm. Wherein, when the second end 203a2 of the suction tube 203a moves down to the limit position along the direction of the height H, preferably, the second end 203a2 extends to a position of 0~5mm from the bottom surface 300a, more preferably 0~ The position of 3mm, and the position of 0.5~1mm is better, so as to facilitate the suction from the closest to the bottom surface.

For ease of understanding, the foregoing content will not be repeated.

Refer to FIG. 4, which is a schematic structural view of the second embodiment of the centrifuge tube of the present invention.

As shown in FIG. 4, the centrifuge tube 2 further includes an auxiliary suction tube 203b. The auxiliary suction pipe 203b may include a third end 203b1 and a fourth end 203b2. The third end 203b1 can be connected and penetrate the upper cover 200. The fourth end 203b2 can extend into the accommodating space. The auxiliary suction tube 203b is closer to the bottle wall 300b than the suction tube 203a. In one embodiment, preferably, the fourth end 203b2 extends to a position of 8~20mm from the bottom surface 300a; more preferably a position of 10~17mm; and still more preferably a position of 13~15mm, so as to be controlled by The length of the suction pipe 203a is controlled uniformly to control the composition of the liquid to be centrifuged.

Referring to FIGS. 5 to 7, it is a schematic structural view, a top view and a side view of the upper cover of the second embodiment of the centrifuge tube of the present invention.

As shown in FIGS. 5 to 7, the upper cover 200 of the centrifuge tube 2 may include two injection holes 201 and one air hole 202. Although the centrifuge tube 2 has both the suction tube 203a and the auxiliary suction tube 203b, the upper cover 200 of the centrifuge tube 2 still needs to retain the air holes 202 to facilitate the suction or injection of liquid. The air hole 202 is spatially communicated with the accommodating space of the bottle body 300. However, in actual use, the position of the air hole 202 is higher than the liquid level.

Compared with the suction pipe 203a, the auxiliary suction pipe 203b is closer to the bottle wall 300b, which means that the injection hole 201 corresponding to the auxiliary suction pipe 203a is closer to the edge of the upper cover 200 than the injection hole 201 corresponding to the suction pipe 203a. In one embodiment, the center of the upper cover 200 is at a distance L1 from the center of the injection hole 201 of the suction tube 203a. The distance L2 between the center of the air hole 202 and the center of the injection hole 201 corresponding to the suction tube 203a. The distance L3 between the center of the injection hole 201 corresponding to the suction pipe 203a and the center of the injection hole 201 corresponding to the auxiliary suction pipe 203b. Preferably, the distance L1 is 0 to 5 mm; more preferably 0 to 3 mm; and still more preferably 0 to 1 mm, so as to facilitate extraction from the lowest part of the middle bottom. Preferably, the distance L2 is 7-12 mm; more preferably 8-11 mm; and even more preferably 9-10 mm, so as to facilitate injection and suction without interfering with the injection hole. Preferably, the distance L3 is 7-12 mm; more preferably 8-11 mm; and even more preferably 9-10 mm, so as to facilitate injection and suction without interfering with the injection hole. In one embodiment, the distance L1 is not zero. In one embodiment, the distance L2 is equal to the distance L3.

Refer to Figure 8 and Figure 9, which are the structural schematic diagram of the third embodiment of the centrifugal tube and the structural schematic diagram of the suction tube of the creation respectively.

As shown in the figure, in the centrifuge tube 3, the suction tube 203a may further include an outer tube 204 and an inner tube 205. The outer tube 204 is rotatably sleeved outside the inner tube 205. The inner tube 205 may have an inner tube upper opening 205a and an inner tube lower opening 205b. The upper opening 205a of the inner tube is closer to the upper opening 301 than the lower opening 205b of the inner tube. The outer tube 204 may have an outer tube upper opening 204a and an outer tube lower opening 204b. The upper opening 204a of the outer tube is closer to the upper opening 301 than the lower opening 204b of the outer tube. In addition, the upper cover 200 may have a track corresponding to the suction tube 203a to rotate the outer tube 204 or the inner tube 205. In one embodiment, the lower end surface of the upper cover 200 may have T rows of grooves to facilitate assembly and rotation of the inner tube 205 from a fixed position from bottom to top. The inner tube 205 can be connected to the rotating rotary rod and assembled from bottom to top along the direction of height H. The inner tube 205 externally rotates the rotary rod to the upper cover 200.

In an embodiment, the center of the upper opening 205a of the inner tube and the center of the lower opening 205b of the inner tube are straight along the direction of height H, and the center of the upper opening 204a of the outer tube and the center of the lower opening 204b of the outer tube are along the height The direction of H is not a straight line. In an embodiment, the center of the upper opening 204a of the outer tube and the center of the lower opening 204b of the outer tube are aligned along the direction of height H, and the center of the upper opening 205a of the inner tube and the center of the lower opening 205b of the inner tube are along the height The direction of H is not a straight line.

The center of the upper opening 204a of the outer tube and the center of the lower opening 204b of the outer tube are in a line along the direction of height H, and the center of the upper opening 205a of the inner tube and the center of the lower opening of the inner tube 205b are not in the direction of height H In the case of a straight line, the bottom of the outer tube 204 may include two openings on the same side, that is, the upper opening 204a of the outer tube and the lower opening 204b of the outer tube. When the inner tube 205 is rotated so that the upper opening 205a of the inner tube corresponds to the upper opening 204a of the outer tube, the upper liquid can be extracted, that is, corresponding to the upper part in the area AA; and when the inner tube 205 is rotated, the lower opening 205b of the inner tube is aligned with When the lower opening 204b of the outer tube corresponds, a lower liquid can be drawn, that is, corresponds to the lower part in the area AA.

It should be noted that the position of the opening 205a on the inner tube of the centrifuge tube 3 may correspond to the position of the fourth end 203b2 of the auxiliary suction tube 203b of the centrifuge tube 2, and the position of the opening 205b of the inner tube of the centrifuge tube 3 may correspond to At the position of the second end 203a2 of the suction tube 203a of the centrifuge tube 2.

Refer to Figure 10, which is a schematic diagram of the structure of the bottle body of the created centrifuge tube.

As shown in FIG. 10, the centrifuge tube 4 includes a bottle body 300, an upper cap 200, and a soft stopper 400. The bottle body 300 has an upper opening 301 and a lower opening 302. The areas and shapes of the upper opening 301 and the lower opening 302 may be the same or different according to the type of liquid contained. The inner diameter of the lower end surface of the upper cover 200 may be smaller than the outer diameter of the upper opening 301 to seal the upper opening 301 by the upper cover 200.

In one embodiment, the upper cover 200 is connected to the upper part of the bottle body 300 and seals the upper opening 301 of the bottle body 300. The inner diameter of the bottle body 300 is preferably 22 to 27 mm; more preferably 23 to 26 mm; and still more preferably 24 to 25 mm, which is advantageous for handling more liquids. The outer diameter of the upper opening 301 of the bottle body 300 is preferably 25 to 30 mm; more preferably 26 to 29 mm; and still more preferably 27 to 28 mm, thereby facilitating opening and closing operations; within the upper opening 301 of the bottle body 300 The diameter is preferably from 23 to 28 mm; more preferably from 24 to 27 mm; and still more preferably from 25 to 26 mm, so as to facilitate a complete seal with the bottle body. The outer diameter of the lower opening 302 of the bottle body 300 is preferably 13 to 18 mm; more preferably 14 to 17 mm; and more preferably 15 to 16 mm to facilitate sealing; the inner diameter of the lower opening 302 of the bottle body 300 is preferably 11~16mm; more preferably 12~15mm; and more preferably 13~14mm, which facilitates extraction.

The soft stopper 400 is connected to the lower portion of the bottle body 300 and has a plurality of soft stopper sealing rings on the outer peripheral surface of the soft stopper 400. The soft stopper sealing ring can make the soft stopper 400 tightly seal the lower opening 302 of the bottle body 300. The outer diameter of the upper end surface of the soft plug 400 is larger than the inner diameter of the lower opening 302 to seal the lower opening 302 by the soft plug 400. The soft plug 400 is an elastic body for puncturing a hole. For example, the soft plug 400 may be a silicone plug. In one embodiment, if the soft plug 400 is a silicone plug, the soft plug 400 can provide the needle to repeatedly puncture and extract the required liquid, while still effectively reducing the time and contact area of the liquid sealed in the centrifuge tube 4 in contact with the external environment Therefore, the storage time and freshness of the liquid contained in the centrifuge tube 4 can be greatly improved.

The centrifuge tube 4 may further include a lower cover 500. The lower cap 500 is connected to the lower part of the bottle body 300 and has a plurality of lower cap sealing rings 501 located at the upper part of the lower cap 500. The lower cap sealing ring 501 can tightly connect the lower cap 500 to the lower part of the bottle body 300. The lower cover 500 has a rounded table shape, so when the centrifuge tube 4 includes the lower cover 500, the centrifuge tube 4 can match the shape of the rotor of a commercially available centrifuge, so the design can be used directly without changing the design of the commercially available centrifuge. The centrifuge tube 4 is centrifuged. In one embodiment, the height of the lower cover 500 is preferably 17 to 22 mm; more preferably 18 to 21 mm; and still more preferably 19 to 20 mm, so that the overall size can be used for centrifuges of universal specifications. The outer diameter of the upper end surface of the lower cover 500 is preferably 19 to 24 mm; more preferably 20 to 23 mm; and still more preferably 21 to 22 mm, thereby facilitating sealing with the bottle body. The outer diameter of the lower end surface of the lower cover 500 is preferably 5 to 10 mm; more preferably 6 to 9 mm; and still more preferably 7 to 8 mm, which is beneficial to a general-purpose centrifuge rotor.

Refer to FIG. 11, which is a schematic structural diagram of the bottle holder of the created centrifuge tube.

As shown in FIG. 11, the centrifuge tube 4 may further include a bottle holder 700. The bottle fixing frame 700 has an accommodating space for accommodating the bottle body 300, so the centrifuge tube 4 can be stably placed in the bottle fixing frame 700 for the user to perform subsequent actions. The centrifuge tube 4 may further include a base 800. The bottle holder 700 has an upper inner diameter and a lower inner diameter, and the inner diameter of the upper end is smaller than the inner diameter of the lower end, and the inner diameter of the bottle holder 700 gradually increases from the inner diameter of the upper end to the inner diameter of the lower end, and the outer diameter of the bottle 300 The diameter is between the inner diameter of the upper end and the inner diameter of the lower end of the bottle fixing frame 700, so that the bottle body 300 is fixed in the bottle fixing frame 700. In an embodiment, the inner diameter of the upper end of the bottle holder 700 is preferably 24 to 29 mm; more preferably 25 to 28 mm; and still more preferably 26 to 27 mm, which facilitates the fixing of the bottle and operation. The inner diameter of the lower end of the bottle holder 700 is preferably 54 to 59 mm; more preferably 55 to 58 mm; and still more preferably 56 to 57 mm, which facilitates fixing and stabilizing the device with the base.

The base 800 is connected to the bottle holder 700, and the base 800 provides a counterweight that supports the centrifuge tube 4 and the bottle holder 700, and is used to prevent the centrifuge tube 4 from tipping. The base 800 has a groove 801, the outer diameter of the groove 801 is larger than the outer diameter of the lower end of the bottle holder 700, so that the bottle holder 700 is fixed on the base 800 by the groove 801. The base 800 can be made of metal, and the weight can be balanced by the high density of metal. In addition, the bottle holder 700 can be used to stably place the centrifuge tube 4 and can also be used to adjust the height of the bottom of the bottle body 300 of the centrifuge tube 4 from the operating position of the operating table or tabletop, that is, to adjust The height of the soft plug 400 from the user's operation position. In one embodiment, the height of the soft stopper 400 from the user's operating position is preferably 3-8 mm; more preferably 4-7 mm; and still more preferably 5-6 mm, which facilitates the user to collect the centrifuge by the needle Liquid.

Refer to FIG. 12, which is a schematic diagram of the structure of the outlet holder of the created centrifuge tube. As shown in FIG. 12, the centrifuge tube 4 may further include a lead-out holder 600. The outer diameter of the outlet fixing frame 600 is between the upper end inner diameter and the lower end inner diameter of the bottle fixing frame 700, so that the outlet fixing frame 600 is disposed in the bottle fixing frame 700 for fixing the outlet piece 900. The lead-out holder 600 includes a through hole 601 having a height h and a diameter R.

The lead-out member 900 can be connected to the lead-out holder 600, so the lead-out holder 600 controls the relative position of the lead-out holder 600 and the lead-out member 900 by controlling the height h and the diameter R. In one embodiment, the height h of the through-hole 601 is preferably 13-18 mm; more preferably 14-17 mm; and still more preferably 15-16 mm, which facilitates fixing the extraction needle and the extension tube. The diameter R of the through hole 601 is preferably 4 to 9 mm; more preferably 5 to 8 mm; and still more preferably 6 to 7 mm, which facilitates fixing the extension tube.

The lead-out 900 may include a needle 901, an extension tube 902, and a collection bottle 903. The needle 901 includes a first needle end 901a and a second needle end 901b. The first needle end 901a extends into the interior of the bottle body 300, and the second needle end 901b extends to the through hole 601, so that the needle 901 pierces the soft stopper through the through hole 601 400. The extension tube 902 is hollow and cylindrical, and includes a first extension end 902a and a second extension end 902b. The first extension end 902a is connected to the second needle end 901b of the needle 901. The collection bottle 903 is connected to the second extension end 902b of the extension tube 902. Among them, the accommodating space of the bottle body 300 of the centrifuge tube 4, the needle 901, the extension tube 902, and the collection bottle 903 are spatially connected. In addition, the outlet 900 may further include a multi-way valve, for example, a three-way valve.

In one embodiment, the needle 901 pierces the soft stopper 400 of the centrifuge tube 4 through the through hole 601 of the outlet holder 600, that is, the needle 901 contacts and draws the liquid contained in the bottle body 300 of the centrifuge tube 4. Then, since the needle 901 and the extension tube 902 are connected to each other, the centrifuged liquid can flow from the needle 901 along the extension tube 902. Next, since the extension tube 902 and the collection bottle 903 are connected to each other, the centrifuged liquid can then flow from the extension tube 902 into the collection bottle 903 for collection.

The centrifuge tube 4 may further include a sealing cover 100 connected to the upper cover 200 and sealing the injection hole 201 and the air hole 202. For example, the sealing cover 100 may have a first convex portion 101 corresponding to the injection hole 201 and a second convex portion 102 corresponding to the air hole 202.

By way of example, the use of centrifuge tubes will be described in detail below.

First, place the whole blood in a centrifuge tube, and after centrifugation, the blood is divided from top to bottom: a translucent to pale yellow upper layer of plasma, a white middle layer rich in platelets and white blood cells, and rich in The dark red underside of the red blood cells.

When using centrifuge tube 1:

The height of the centrifuge tube is 125mm, and the spiral structure is used to move up and down. When the second end 203a2 of the suction tube 203a moves upward to the limit position, the second end 203a2 extends to 14mm away from the bottom surface 300a, and is called the first position. When the second end 203a2 of the suction tube 203a moves downward to the limit position The second end 203a2 extends to 1mm from the bottom surface 300a and is called the second position.

First, the first centrifugation is performed, and then the suction tube 203a is placed at the second position and red blood cells are drawn. The second centrifugation is performed, the suction tube 203a is placed at the first position, and the upper platelet-poor plasma (PPP) is drawn. The suction tube 203a is placed in the second position, and after mixing, the platelet-rich plasma (PRP) is drawn. Among them, the centrifugal force of the first centrifugation was 2300g for 3 minutes. The centrifugal force of the second centrifugation was 3000g for 3 minutes.

When using centrifuge tube 2:

The height of the centrifuge tube is 125mm, and the spiral structure is used to move up and down. The second end 203a2 of the suction tube 203a extends to 1 mm from the bottom surface 300a and is called a second position, and the fourth end 203b2 of the auxiliary suction tube 203b extends to 14 mm from the bottom surface 300a and is called a first position. The remaining steps are as in the case where the centrifuge tube 1 is used.

When using centrifuge tube 3:

The height of the centrifuge tube is 125mm. The upper opening 205a of the inner tube and the upper opening 204a of the outer tube are located at 14mm from the bottom surface 300a, and are called the first position, and the lower opening 205b of the inner tube and the lower opening 204b of the outer tube are located at 1mm from the bottom surface, and are called For the second position. The remaining steps are as in the case where the centrifuge tube 1 is used.

When using centrifuge tube 4:

When using the centrifuge tube 4, since the length of the needle 901 will correspond to the solution to be drawn, if you want to collect the lower layer, choose a shorter needle 901, and if you want to collect the middle layer, you must choose the one that is used to collect the lower layer. Needle 901 is longer needle 901. At the same time, a three-way valve can be further installed on the centrifuge tube 4. The first end of the three-way valve communicates with the needle 901 and the extension tube 902; the second end of the three-way valve communicates with the collection bottle 903; and the third end of the three-way valve communicates with the extraction device, so extraction can be provided by the extraction device With force, the liquid contained in the bottle body 300 of the centrifuge tube 4 is drawn into the collection bottle 903 through the needle 901 and the extension tube 902. For example, the extraction device may be a device such as a syringe that can provide extraction force. In this case, if you only want to collect the lower layer, you can accurately know the interface position of the different layers by observing the color difference seen through the transparent extension tube 902, such as the dark red lower layer and the white middle layer. At the interface, users can only collect specific liquids.

Following the above, the centrifuge tube 1 and the centrifuge tube 2 were compared with the commercially available products as comparative examples for centrifugal efficiency. The commercially available product is YK PRP kit. The results are shown in Table 1.

Table 1

As shown in Table 1, the centrifuge tube representing this creation actually has an effective centrifugal effect.

The above is only exemplary, and not restrictive. Any equivalent modifications or changes made without departing from the spirit and scope of this creation should be included in the scope of the patent application.

1, 2, 3, 4: centrifuge tube 100: sealing cap 101: The first convex part 102: second convex 200: upper cover 201: injection hole 202: stomata 203a: Suction tube 203a1: the first end 203a2: the second end 203b: auxiliary suction tube 203b1: third end 203b2: the fourth end 204: outer tube 204a: opening in the outer tube 204b: Opening under the outer tube 205: Inner tube 205a: opening in the inner tube 205b: Opening under the inner tube 206: Spiral structure 300: bottle body 300a: underside 300b: bottle wall 301: Upper opening 302: Lower opening 400: soft stopper 500: Lower cover 501: Lower cover sealing ring 600: export piece holder 601: through hole 700: bottle holder 800: base 801: groove 900: Export 901: Needle 901a: first pin end 901b: second pin end 902: Extension tube 902a: the first extension 902b: Second extension 903: Collection bottle AA: Area h, H: height L1, L2, L3: distance R: diameter

Figure 1 is a schematic structural view of the first embodiment of the centrifuge tube created in this invention. Figure 2 is a side view of the upper cover of the first embodiment of the centrifuge tube of this creation. Figure 3 is a schematic diagram of the suction tube of the first embodiment of the centrifuge tube created in this invention. Figure 4 is a schematic structural view of the second embodiment of the centrifuge tube created. Figure 5 is a schematic diagram of the structure of the upper cover of the second embodiment of the centrifuge tube. Figure 6 is a top view of the upper cover of the second embodiment of the centrifuge tube created in this invention. Figure 7 is a side view of the upper cover of the second embodiment of the centrifuge tube created in this invention. Figure 8 is a schematic structural view of the third embodiment of the centrifuge tube created in this invention. Figure 9 is a schematic diagram of the suction tube of the third embodiment of the centrifuge tube created in this invention. Figure 10 is a schematic structural view of another embodiment of the centrifuge tube created. Figure 11 is a schematic structural view of another embodiment of the centrifuge tube created. FIG. 12 is a schematic structural view of another embodiment of the centrifuge tube created.

1: Centrifuge tube

200: upper cover

201: injection hole

202: stomata

203a: Suction tube

203a1: the first end

203a2: the second end

300: bottle body

300a: underside

300b: bottle wall

301: Upper opening

H: height

Claims (12)

A centrifuge tube, comprising: A bottle body has an accommodating space formed by a bottom surface and a bottle wall, the lower part of the accommodating space is in the shape of a round table, the bottle body has an upper opening, and the distance from the upper opening to the bottom surface Is a height An upper cap connected to the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cap corresponds to the outer diameter of the upper opening to seal the upper opening with the upper cap; and A suction tube, including a first end and a second end, the first end is connected to and penetrates the upper cover, and the second end extends in the accommodating space; Wherein the second end extends to a position of 0~5mm from the bottom surface. The centrifuge tube as described in item 1 of the patent application range, wherein the suction tube moves up and down along the direction of the height. The centrifuge tube as described in item 2 of the patent application scope, wherein when the second end moves upward to the limit position along the direction of the height, the second end extends to a position 8 to 20 mm from the bottom surface; and the second When the end moves down to the limit position along the direction of the height, the second end extends to a position of 0~3mm from the bottom surface. The centrifuge tube as described in item 1 of the patent application scope further includes: An auxiliary suction pipe includes a third end and a fourth end, the third end is connected to and penetrates the upper cover, and the fourth end extends in the accommodating space, and compared to the suction pipe, the auxiliary suction The tube is closer to the bottle wall. The centrifuge tube as described in item 4 of the patent application scope, wherein the fourth end extends to a position 8 to 20 mm from the bottom surface. The centrifuge tube as described in item 1 of the patent application scope, wherein the suction tube further comprises: An inner tube having an upper opening of the inner tube and a lower opening of the inner tube, and the upper opening of the inner tube is closer to the upper opening than the lower opening of the inner tube; and An outer tube, sleeved outside the inner tube, having an upper opening of the outer tube and a lower opening of the outer tube and the upper opening of the outer tube is closer to the upper opening than the lower opening of the outer tube; Wherein, the center of the upper opening of the inner tube and the center of the lower opening of the inner tube are linear along the direction of the height, and the center of the upper opening of the outer tube and the center of the lower opening of the outer tube are not along the direction of the height Is a straight line; or the center of the upper opening of the outer tube and the center of the lower opening of the outer tube are in a line along the height, and the center of the upper opening of the inner tube and the center of the lower opening of the inner tube are along the height The direction is not a straight line. A centrifuge tube, comprising: A bottle body is hollow cylindrical and has an upper opening and a lower opening; An upper cap connected to the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cap corresponds to the outer diameter of the upper opening to seal the upper opening with the upper cap; and A soft stopper, connected to the lower part of the bottle body, and having a plurality of soft stopper sealing rings on the outer peripheral surface of the soft stopper, and the outer diameter of an upper end surface of the soft stopper corresponds to the inner diameter of the lower opening, to Seal the lower opening with the soft plug; Among them, the soft plug is an elastic body used for puncturing a hole. The centrifuge tube as described in item 7 of the patent application scope further includes: A lower cap is connected to the lower part of the bottle body and has a plurality of lower cap sealing rings located on the upper part of the lower cap, and the lower cap is in the shape of a rounded table, and the outer diameter of the upper end surface of the lower cap is greater than the lower The outer diameter of the lower end surface of the cap, and the outer diameter of the upper end surface of the lower cap corresponds to the inner diameter of the bottle body. The centrifuge tube as described in item 7 of the patent application scope further includes: A bottle body fixing frame has an accommodating space for accommodating the bottle body, and the bottle body fixing frame has an upper end inner diameter and a lower end inner diameter, the upper end inner diameter is smaller than the lower end inner diameter, and the bottle body The inner diameter of the fixing frame gradually increases from the inner diameter of the upper end to the inner diameter of the lower end, and the outer diameter of the bottle body is between the inner diameter of the upper end and the inner diameter of the lower end; and A base is connected to the bottle fixing frame and has a groove, the outer diameter of the groove corresponds to the outer diameter of a lower end of the bottle fixing frame, so that the bottle fixing frame is fixed to the bottle through the groove On the base. The centrifuge tube as described in item 9 of the patent application scope further includes: An outlet fixing frame is disposed in the bottle fixing frame and includes a through hole, and the outer diameter of the outlet fixing frame is between the inner diameter of the upper end and the inner diameter of the lower end of the bottle fixing frame. The centrifuge tube as described in item 10 of the patent application scope further includes: An export piece is connected to the fixing rack of the export piece, and the export piece includes: A needle includes a first needle end and a second needle end, the first needle end extends into the bottle body, and the second needle end extends to the through hole, so that the needle pierces the through the through hole Soft plug An extension tube, which is hollow and cylindrical, and includes a first extension end and a second extension end, the first extension end being connected to the second needle end of the needle; and A collection bottle connected to the second extension end of the extension tube; Wherein, the bottle body, the needle, the extension tube and the collection bottle are spatially connected. The centrifuge tube as described in item 9 of the patent application scope further includes: An injection hole is provided on the upper cover and penetrates the upper cover; An air hole provided on the upper cover and penetrating the upper cover; and A sealing cover connected to the upper cover and including a first convex portion corresponding to the injection hole and a second convex portion corresponding to the air hole, so that the sealing cover seals the injection hole and the air hole; Wherein, the inner diameter of the injection hole is larger than the inner diameter of the air hole.

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