CN212632736U - Centrifugal tube - Google Patents

Abstract

The utility model discloses a centrifuge tube, it contains: the bottle body is provided with an accommodating space formed by a bottom surface and a bottle wall, the lower part of the accommodating space is in an inverted circular truncated cone shape, the bottle body is provided with an upper opening, and the distance from the upper opening to the bottom surface is the height; an upper cover connected to the upper portion of the bottle body, and having a lower end surface with an inner diameter corresponding to an outer diameter of the upper opening to seal the upper opening through the upper cover; the suction pipe comprises a first end and a second end, the first end is connected with and penetrates through the upper cover, and the second end extends into the accommodating space; wherein the second end extends to a position 0-5 mm away from the bottom surface.

Description

Centrifugal tube

Technical Field

The utility model relates to a centrifuging tube, concretely relates to centrifuging tube that has the suction tube and can gain the centrifugate easily.

Background

The centrifugation step is widely used in the fields of chemical engineering, petroleum, food processing, etc. because it can effectively separate different substances having different sedimentation rates and densities in a mixture. Among them, centrifuge tubes are often used to contain the liquid to be centrifuged and are coupled to centrifuges to facilitate the centrifugation step.

At present, the parts of the centrifugal tube on the market can be mainly divided into an upper cover and a bottle body. The upper cover is mainly used for sealing the bottle body to prevent the liquid contained in the centrifugal tube from leaking, and simultaneously provides a bottle body supporting force to prevent the bottle body from being damaged when the centrifugation step is carried out. The bottle can be classified into plastic, glass and stainless steel according to the material, also can divide into flat bottom, round bottom or toper end according to the bottom shape, but whatever bottle chooses for use, mainly is in order to collocate the liquid kind and the centrifugal speed of treating the centrifugation.

However, for those skilled in the art, after centrifugation using a commercially available centrifuge tube containing a liquid to be centrifuged, if the centrifuged liquid has an interface, i.e. the centrifuged liquid is divided into at least two layers, the supernatant liquid can only be extracted first and then the subnatant liquid can only be extracted by using a pipette; or directly using a pipette to draw the underlying liquid directly through the interface. However, this method is very likely to cause the interface after centrifugation to be damaged, and the separation effect is greatly reduced.

SUMMERY OF THE UTILITY MODEL

The utility model provides a centrifuge tube, through setting up the suction tube in the upper shed, let the user can gain through centrifugal liquid easily.

In order to achieve the above object, the present invention provides a centrifuge tube, which comprises: the bottle body is provided with an accommodating space formed by a bottom surface and a bottle wall, the lower part of the accommodating space is in an inverted circular truncated cone shape, the bottle body is provided with an upper opening, and the distance from the upper opening to the bottom surface is the height; an upper cover connected with the upper part of the bottle body, wherein the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening, and the upper opening is sealed by the upper cover; the suction pipe comprises a first end and a second end, the first end is connected with and penetrates through the upper cover, and the second end extends into the accommodating space; wherein the second end extends to a position 0-5 mm away from the bottom surface.

Alternatively, the suction pipe is moved up and down in the height direction.

Optionally, when the second end moves upwards along the height direction to the limit position, the second end extends to a position 10-15 mm away from the bottom surface; and when the second end moves downwards along the height direction to the limit position, the second end extends to a position 0-3 mm away from the bottom surface.

Optionally, the centrifuge tube further comprises: contain the supplementary suction tube of third end and fourth end, the upper cover is connected and run through to the third end, and the fourth end extends in the accommodation space, and compares in the suction tube, supplementary suction tube is more close to the bottle wall.

Optionally, the fourth end extends to a position 10-15 mm from the bottom surface.

Optionally, the extraction duct further comprises: an inner tube having an inner tube upper opening and an inner tube lower opening, the inner tube upper opening being closer to the upper opening than the inner tube lower opening; and an outer tube sleeved outside the inner tube and having an outer tube upper opening and an outer tube lower opening, wherein the outer tube upper opening is closer to the upper opening than the outer tube lower opening; the center of the upper opening of the inner pipe and the center of the lower opening of the inner pipe are straight lines along the height direction, and the center of the upper opening of the outer pipe and the center of the lower opening of the outer pipe are not straight lines along the height direction; or the center of the upper opening of the outer pipe and the center of the lower opening of the outer pipe are in a straight line along the height direction, and the center of the upper opening of the inner pipe and the center of the lower opening of the inner pipe are not in a straight line along the height direction.

To achieve another object, the present invention provides a centrifuge tube, which comprises: the centrifugal tube is in a hollow cylindrical shape and is provided with a bottle body with an upper opening and a lower opening; an upper cover connected with the upper part of the bottle body, wherein the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening, and the upper opening is sealed by the upper cover; the soft plug is connected with the lower part of the bottle body and is provided with a plurality of soft plug sealing rings positioned on the peripheral surface of the soft plug, the outer diameter of the upper end surface of the soft plug corresponds to the inner diameter of the lower opening, and the lower opening is sealed by the soft plug; wherein, the soft plug is used for puncturing the hole-forming elastomer.

Optionally, the centrifuge tube further comprises: the lower cover is connected with the lower part of the bottle body and is provided with a plurality of lower cover sealing rings positioned on the upper part of the lower cover, the lower cover is in the shape of an inverted circular truncated cone, the outer diameter of the upper end surface of the lower cover is larger than that of the lower end surface of the lower cover, and the outer diameter of the upper end surface of the lower cover corresponds to the inner diameter of the bottle body.

Optionally, the centrifuge tube further comprises: the bottle body fixing frame is provided with a containing space for containing a bottle body, the bottle body fixing frame is provided with an upper end inner diameter and a lower end inner diameter, the upper end inner diameter is smaller than the lower end inner diameter, the inner diameter of the bottle body fixing frame is gradually increased from the upper end inner diameter to the lower end inner diameter, and the outer diameter of the bottle body is between the upper end inner diameter and the lower end inner diameter; and a base connected with the bottle body fixing frame and provided with a groove, wherein the outer diameter of the groove corresponds to the outer diameter of the lower end of the bottle body fixing frame, so that the bottle body fixing frame is fixed on the base through the groove.

Optionally, the centrifuge tube further comprises: the guide part fixing frame is arranged in the bottle body fixing frame and comprises a through hole, and the outer diameter of the guide part fixing frame is between the inner diameter of the upper end and the inner diameter of the lower end of the bottle body fixing frame.

Optionally, the centrifuge tube further comprises: a lead-out piece connected to the lead-out piece fixing frame, and the lead-out piece comprises: a needle head comprising a first needle end and a second needle end, the first needle end extending into the bottle body, and the second needle end extending into the through hole, so that the needle head penetrates the soft plug through the through hole; the centrifugal tube is hollow and cylindrical and comprises a first extension end and an extension tube of a second extension end, and the first extension end is connected with the second needle end of the needle head; and a collection bottle connected to the second extension end of the extension tube; wherein the bottle body, the needle, the extension tube and the collection bottle are communicated spatially.

Optionally, the centrifuge tube further comprises: an injection hole arranged on the upper cover and penetrating through the upper cover; the air hole is arranged on the upper cover and penetrates through the upper cover; and a sealing cover connected with the upper cover and including a first convex part corresponding to the injection hole and a second convex part corresponding to the air hole, so that the sealing cover seals the injection hole and the air hole; wherein the inner diameter of the injection hole is larger than that of the air hole.

The centrifuge tube provided by the utility model has the advantages that,

(1) in an embodiment, because the utility model provides a centrifuging tube has the suction tube of connecting in the upper cover, because before using the centrifuging tube to centrifuge, the suction tube has extended in the accommodation space, consequently can directly derive the liquid after the centrifugation via the cavity pipe diameter department of suction tube after the centrifugation, and reach the purpose of direct layering.

(2) In an embodiment, because the utility model provides an absorption tube of centrifuging tube can reciprocate along the direction of height, consequently can adjust the position of absorption tube according to the position of the layering department of the liquid after the centrifugation, and reaches the purpose of the component of the liquid that the adjustment was expected to absorb.

(3) In an embodiment, because the utility model discloses the centrifuging tube still further contains supplementary suction tube except having the suction tube, consequently can be according to specific order, absorb the liquid after the centrifugation respectively in suction tube and the supplementary suction tube to the step of the repeated centrifugation of collocation, and can further adjust the component of the liquid of wanting to absorb.

(4) In an embodiment, because the utility model provides an absorption tube of centrifuging tube has inner tube and outer tube that can rotate each other, and inner tube and outer tube have upper shed and the under shed that corresponds each other, consequently can be through rotatory to specific position, the position that the adjustment absorption tube took out, and reach the purpose of the component of the liquid that the adjustment was expected to absorb.

(5) In an embodiment, because the utility model provides a centrifuging tube has the cork, consequently after the liquid of holding in the bottle of centrifuging tube is through centrifugation and layering, the user can be through derivation piece puncture cork such as syringe needle for the sealed liquid fluid circulation of cork is to derivation piece, then collects, thereby reaches effective collection and can avoid the purpose that layering liquid mixes again at not destroying centrifugal interface.

(6) In an embodiment, because the utility model provides a centrifuging tube has the derivation piece mount, consequently has at the syringe needle of selling under the gauge size that uses its external diameter size and length as the standard, through the height and the diameter of the through-hole of adjustment derivation piece mount, controls the syringe needle and inserts the degree of depth of cork through the puncture of derivation piece mount from bottom to top, and then reaches the purpose of the kind of the layering liquid of selecting the extraction standardly. For example, if the liquid contained in the bottle body is centrifuged and then sequentially divided into an upper layer, a middle layer and a lower layer, the extracted layers can be selected according to the sizes of the needle head and the guide piece fixing frame.

(7) In an embodiment, because the utility model provides a centrifuging tube has that the pipe diameter is thin and can be the extension pipe of transparent plastic material, so when deriving the liquid after the centrifugation, can observe the interface place department of layering more accurately to reach more meticulous layering purpose.

(8) In an embodiment, because the utility model discloses the centrifuging tube has bottle mount and base, consequently can be different via the counter weight to stabilize the centrifuging tube, reach and conveniently take the purpose.

Drawings

Figure 1 is the utility model discloses centrifuge tube embodiment one's structural schematic.

Figure 2 is the top cover side view of the centrifuge tube of the first embodiment of the present invention.

Fig. 3a and fig. 3b are schematic diagrams of the structure of the suction tube according to the first embodiment of the centrifugal tube of the present invention.

Figure 4 is the second embodiment of the centrifuge tube of the present invention.

Figure 5 is the second embodiment of the centrifuge tube of the present invention.

Figure 6 is the top view of the second embodiment of the centrifuge tube of the present invention.

Figure 7 is the top cover side view of the second embodiment of the centrifuge tube of the present invention.

Figure 8 is the third structure diagram of the centrifuge tube embodiment of the present invention.

Figure 9 is the utility model discloses third suction tube structure sketch map of centrifuging tube embodiment.

Fig. 10 is a schematic structural view of another embodiment of the centrifuge tube of the present invention.

Fig. 11 is a schematic structural view of another embodiment of the centrifuge tube of the present invention.

Fig. 12 is a schematic structural view of another embodiment of the centrifuge tube of the present invention.

Description of the symbols

1. 2, 3, 4: centrifugal tube

100: sealing cover

101: first convex part

102: second convex part

200: upper cover

201: injection hole

202: air hole

203 a: suction tube

203a 1: first end

203a 2: second end

203 b: auxiliary suction pipe

203b 1: third terminal

203b 2: fourth terminal

204: outer tube

204 a: upper opening of outer tube

204 b: lower opening of outer tube

205: inner pipe

205 a: upper opening of inner tube

205 b: lower opening of inner tube

206: screw structure

300: bottle body

300 a: bottom surface

300 b: bottle wall

301: upper opening

302: lower opening

400: soft plug

500: lower cover

501: lower cover sealing ring

600: lead-out piece fixing frame

601: through hole

700: bottle body fixing frame

800: base seat

801: groove

900: lead-out piece

901: needle head

901 a: first needle end

901 b: second needle end

902: extension pipe

902 a: first extension end

902 b: second extension end

903: collecting bottle

AA: region(s)

h. H: height

L1, L2, L3: distance between two adjacent plates

R: diameter of

Detailed Description

The following describes the embodiments of the present invention with reference to the accompanying drawings.

In order to facilitate understanding of the technical features, contents and advantages of the present invention and the functions achieved thereby, the present invention will be described in detail with reference to the accompanying drawings, wherein the accompanying drawings are used only for illustration and the supplementary specification, and not necessarily for the real proportion and the precise configuration after the implementation of the present invention, so that the application scope of the present invention in the actual implementation should not be read and limited with reference to the proportion and the configuration relation of the accompanying drawings. And for ease of understanding, like elements in the following embodiments are illustrated with like reference numerals.

In the description of the present invention, it should be noted that, unless explicitly stated or limited otherwise, the terms "connected" and "disposed" and the like are to be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases for those skilled in the art.

Referring to fig. 1, it is a schematic structural diagram of an embodiment of the centrifuge tube of the present invention.

As shown in fig. 1, the centrifuge tube 1 includes a bottle 300, an upper cap 200, and a suction tube 203 a.

The bottle 300 may have a receiving space formed by a bottom surface 300a and a wall 300b, and the receiving space is used for receiving a liquid, a suspension liquid, a colloid, etc. to be centrifuged. The bottle body 300 is hollow, and the bottle body 300 may have a desired shape such as a hollow cylindrical shape, a hollow polygonal shape, etc. The bottle 300 may be made of plastic, stainless steel, glass, etc. The lower part of accommodation space can be for the inverted circular truncated cone shape, therefore centrifuging tube 1 can coincide with the rotor shape of commercial centrifuge, so need not change commercial centrifuge's design, and can directly use the utility model discloses centrifuging tube 1 centrifuges. The receiving space of the bottle 300 may have an upper opening 301. The area and shape of the upper opening 301 may be modified according to the kind of the liquid contained therein. The distance from the upper opening 301 to the bottom surface 300a may be a height H. In one embodiment, the height H of the bottle 300 is preferably 110-120 mm; more preferably 112 to 128 mm; and more preferably 114 to 116mm, thereby facilitating a general-purpose commercially available centrifuge and a fixed centrifugation condition.

The upper cap 200 may be coupled to the upper portion of the bottle body 300. The upper cap 200 may be screwed to the bottle 300 or may be directly fastened to the bottle 300. The inner diameter of the lower end surface of the upper cap 200 may correspond to the outer diameter of the upper opening 301, for example, the inner diameter of the lower end surface of the upper cap 200 may be slightly smaller than, equal to, or slightly larger than the outer diameter of the upper opening 301 to seal the upper opening 301 by the upper cap 200. The extraction tube 203a may comprise an extraction tube having a first end 203a1 and a second end 203a 2. The first end 203a1 may be connected to and extend through the cover 200. The second end 203a2 can extend into the accommodating space, so that the centrifugal tube 1 can directly suck the centrifuged lower layer liquid through the suction tube 203 a. In one embodiment, the second end 203a2 preferably extends to a position 0-5 mm away from the bottom surface 300 a; more preferably 0 to 3 mm; and still more preferably 0.5 to 1mm, so that the composition of the liquid to be centrifuged can be uniformly controlled by controlling the length of the aspiration tube 203 a.

In one embodiment, the suction pipe 203a may be disposed at a center of the upper cover 200. However, in another embodiment, the suction pipe 203a may be disposed near the edge of the upper cover 200. For example, the suction pipe 203a may be preferably disposed at a distance of 8 to 20mm from the edge of the upper cover 200; preferably 10 to 17 mm; and more preferably 13-15 mm, to facilitate suction from the nearest bottom surface.

Referring to fig. 2, it is the top cover side view of the first embodiment of the centrifuge tube of the present invention.

As shown in fig. 2, the upper lid 200 of the centrifugal tube 1 includes an injection hole 201 and an air hole 202. The injection hole 201 may be disposed on the upper cap 200 and may penetrate through the upper cap 200 for injecting the liquid to be centrifuged into the bottle 300. The air hole 202 may be disposed on the top cover 200 and may penetrate the top cover 200 to facilitate air exhaust. The inner diameter of the injection hole 201 may be larger than the inner diameter of the air hole 202 so that the liquid to be centrifuged is injected without being affected by the original air pressure in the centrifugal tube 1. In addition, the centrifuge tube 1 may include a sealing cap for sealing the injection hole 201 and/or the air hole 202. The sealing cover is detachably sealed.

Referring to fig. 3a and fig. 3b, which are schematic diagrams of an absorption tube structure according to a first embodiment of the centrifugal tube of the present invention. Fig. 3a and 3b are schematic views of the separation and combination structure of the spiral structure 206 and the upper cover 200. As shown, the aspiration tube of centrifuge tube 1 is moved up and down by helix 206. When the second end 203a2 of the suction pipe 203a moves upward along the height H to the limit position, the second end 203a2 preferably extends to a position 8-20 mm, more preferably 10-17 mm, and even more preferably 13-15 mm from the bottom surface 300 a. When the second end 203a2 of the suction tube 203a moves downward along the height H to the limit position, preferably, the second end 203a2 extends to a position 0-5 mm, more preferably 0-3 mm, and even more preferably 0.5-1 mm away from the bottom surface 300a, thereby facilitating suction from the position closest to the bottom surface.

The foregoing is not repeated to facilitate understanding.

Referring to fig. 4, it is the second structural schematic diagram of the centrifuge tube of the present invention.

As shown in fig. 4, the centrifuge tube 2 further comprises an auxiliary suction tube 203 b. The auxiliary extraction tube 203b may include a third end 203b1 and a fourth end 203b 2. The third end 203b1 can be connected to and extend through the upper cover 200. The fourth end 203b2 can extend into the receiving space. The auxiliary suction pipe 203b is closer to the bottle wall 300b than the suction pipe 203 a. In one embodiment, the fourth end 203b2 preferably extends 8-20 mm from the bottom surface 300 a; more preferably 10 to 17 mm; and still more preferably 13 to 15mm, so that the composition of the liquid to be centrifuged can be uniformly controlled by controlling the length of the aspiration tube 203 a.

Referring to fig. 5 to 7, they are respectively a schematic view, a top view and a side view of an upper cover structure of a second embodiment of the centrifuge tube of the present invention.

As shown in fig. 5 to 7, the upper lid 200 of the centrifuge tube 2 may include two injection holes 201 and one air hole 202. Although the centrifuge tube 2 has the suction tube 203a and the auxiliary suction tube 203b, the upper lid 200 of the centrifuge tube 2 still has the air hole 202 for sucking or injecting liquid. The air hole 202 is spatially communicated with the accommodating space of the bottle 300, however, in actual use, the position of the air hole 202 is higher than the liquid level.

The auxiliary suction pipe 203b is closer to the bottle wall 300b than the suction pipe 203a represents that the injection hole 201 corresponding to the auxiliary suction pipe 203b is closer to the edge of the upper cap 200 than the injection hole 201 corresponding to the suction pipe 203 a. In one embodiment, the center of the upper cover 200 is spaced from the center of the injection hole 201 of the corresponding suction pipe 203a by a distance L1. The center of the air hole 202 is at a distance L2 from the center of the injection hole 201 of the corresponding suction pipe 203 a. The center of the injection hole 201 corresponding to the suction pipe 203a is distant from the center of the injection hole 201 corresponding to the auxiliary suction pipe 203b by a distance L3. Preferably, the distance L1 is 0-5 mm; more preferably 0 to 3 mm; and is preferably 0 to 1mm, so as to facilitate the extraction from the lowest part of the middle bottom. Preferably, the distance L2 is 7-12 mm; more preferably 8 to 11 mm; and is preferably 9-10 mm, thereby facilitating injection and suction without interfering with the injection hole. Preferably, the distance L3 is 7-12 mm; more preferably 8 to 11 mm; and is preferably 9-10 mm, thereby facilitating injection and suction without interfering with the injection hole. In one embodiment, distance L1 is not 0. In one embodiment, distance L2 is equal to distance L3.

Referring to fig. 8 and 9, they are respectively the schematic diagram of the three structures and the schematic diagram of the structure of the suction tube in the embodiment of the centrifugal tube of the present invention.

As shown, in the centrifuge tube 3, the suction tube 203a may further comprise an outer tube 204 and an inner tube 205. The outer tube 204 is rotatably sleeved outside the inner tube 205. The inner tube 205 may have an inner tube upper opening 205a and an inner tube lower opening 205 b. The inner tube upper opening 205a is closer to the upper opening 301 than the inner tube lower opening 205 b. The outer tube 204 may have an outer tube upper opening 204a and an outer tube lower opening 204 b. The outer tube upper opening 204a is closer to the upper opening 301 than the outer tube lower opening 204 b. In addition, the upper cap 200 may have a track corresponding to the suction pipe 203a to rotate the outer pipe 204 or the inner pipe 205. In an embodiment, the lower end surface of the upper cover 200 may have T-shaped grooves to facilitate assembly and rotation of the inner tube 205 from a fixed position from bottom to top. The inner tube 205 may be connected to a rotating swing lever and assembled from bottom to top along the direction of the height H. The inner tube 205 circumscribes the swivel screw to the upper cap 200.

In one embodiment, the center of the inner tube upper opening 205a and the center of the inner tube lower opening 205b are straight along the direction of the height H, and the center of the outer tube upper opening 204a and the center of the outer tube lower opening 204b are not straight along the direction of the height H. In one embodiment, the center of the outer tube upper opening 204a and the center of the outer tube lower opening 204b are aligned along the height H, and the center of the inner tube upper opening 205a and the center of the inner tube lower opening 205b are not aligned along the height H.

In the case that the center of the outer tube upper opening 204a and the center of the outer tube lower opening 204b are aligned along the direction of the height H, and the center of the inner tube upper opening 205a and the center of the inner tube lower opening 205b are not aligned along the direction of the height H, the bottom of the outer tube 204 may include two openings on the same side, i.e., the outer tube upper opening 204a and the outer tube lower opening 204 b. When the inner tube 205 is rotated so that the inner tube upper opening 205a corresponds to the outer tube upper opening 204a, the liquid of the upper layer, that is, the upper portion in the area AA, can be extracted; when the inner tube 205 is rotated such that the inner tube lower opening 205b corresponds to the outer tube lower opening 204b, the lower layer of liquid, i.e., the lower portion in the area AA, can be extracted.

It is particularly noted that the position of the upper opening 205a of the inner tube of the centrifuge tube 3 may correspond to the position of the fourth end 203b2 of the auxiliary aspiration tube 203b of the centrifuge tube 2, and the position of the lower opening 205b of the inner tube of the centrifuge tube 3 may correspond to the position of the second end 203a2 of the aspiration tube 203a of the centrifuge tube 2.

Referring to fig. 10, it is a schematic diagram of the structure of the centrifuge tube bottle of the present invention.

As shown in fig. 10, the centrifuge tube 4 comprises a bottle body 300, an upper cap 200 and a soft plug 400. The bottle 300 has an upper opening 301 and a lower opening 302. The areas and shapes of the upper opening 301 and the lower opening 302 may be the same or different according to the type of liquid to be contained. The inner diameter of the lower end surface of the upper cap 200 may be smaller than the outer diameter of the upper opening 301 to seal the upper opening 301 by the upper cap 200.

In one embodiment, the upper cap 200 is coupled to the upper portion of the bottle body 300 and seals the upper opening 301 of the bottle body 300. The inner diameter of the bottle 300 is preferably 22 to 27 mm; more preferably 23 to 26 mm; and more preferably 24-25 mm, thereby facilitating the handling of more liquid. The outer diameter of the upper opening 301 of the bottle body 300 is preferably 25 to 30 mm; more preferably 26 to 29 mm; and is further preferably 27 to 28mm, thereby facilitating the opening and closing operations; the inner diameter of the upper opening 301 of the bottle 300 is preferably 23 to 28 mm; more preferably 24 to 27 mm; and more preferably 25-26 mm, thereby facilitating the complete sealing with the bottle body. The outer diameter of the lower opening 302 of the bottle 300 is preferably 13 to 18 mm; more preferably 14 to 17 mm; and more preferably 15 to 16mm, thereby facilitating sealing; the inner diameter of the lower opening 302 of the bottle 300 is preferably 11 to 16 mm; more preferably 12 to 15 mm; and more preferably 13 to 14mm, thereby facilitating the extraction.

The cork 400 is coupled to the lower portion of the bottle body 300 and has a plurality of cork sealing rings on the outer circumferential surface of the cork 400. The cork sealing ring allows the cork 400 to tightly seal the lower opening 302 of the bottle body 300. The outer diameter of the upper end surface of the soft plug 400 is larger than the inner diameter of the lower opening 302 to seal the lower opening 302 by the soft plug 400. The soft plug 400 is for piercing a hole-forming elastomer. For example, the soft plug 400 may be a silicone plug. In an embodiment, if the soft plug 400 is a silicone plug, the soft plug 400 can provide the needle head to repeatedly puncture and extract the required liquid, and at the same time, can effectively reduce the time and contact area of the liquid sealed in the centrifuge tube 4 contacting the external environment, thereby greatly increasing the preservation time and freshness of the liquid contained in the centrifuge tube 4.

The centrifuge tube 4 may further comprise a lower cap 500. The lower cap 500 is coupled to the lower portion of the bottle 300 and has a plurality of lower cap sealing rings 501 positioned at the upper portion of the lower cap 500. The lower cap sealing ring 501 allows the lower cap 500 to be tightly coupled to the lower portion of the bottle 300. Lower cover 500 has the shape of the inverted circular truncated cone, consequently when centrifuging tube 4 contains lower cover 500, centrifuging tube 4 can coincide with the rotor shape of the centrifuge on the market, so need not change the design of the centrifuge on the market, and can directly use the utility model discloses centrifuging tube 4 centrifuges. In one embodiment, the height of the lower cover 500 is preferably 17-22 mm; more preferably 18 to 21 mm; and is more preferably 19-20 mm, thereby being beneficial to the centrifuge with the general specification of the whole size. The outer diameter of the upper end surface of the lower cover 500 is preferably 19-24 mm; more preferably 20 to 23 mm; and more preferably 21-22 mm, thereby facilitating sealing with the bottle body. The outer diameter of the lower end face of the lower cover 500 is preferably 5-10 mm; more preferably 6 to 9 mm; and is more preferably 7-8 mm, thereby facilitating the use of centrifuge rotors of general specifications.

Referring to fig. 11, it is the structure diagram of the centrifuge tube bottle fixing frame of the present invention.

As shown in fig. 11, the centrifuge tube 4 may further comprise a bottle holder 700. The bottle holder 700 has a receiving space for receiving the bottle 300, so that the centrifuge tube 4 can be stably placed in the bottle holder 700 for the user to perform subsequent actions. The centrifuge tube 4 may further comprise a base 800. The bottle body holder 700 has an upper inner diameter and a lower inner diameter, and the upper inner diameter is smaller than the lower inner diameter, and the inner diameter of the bottle body holder 700 gradually increases from the upper inner diameter to the lower inner diameter, and the outer diameter of the bottle body 300 is between the upper inner diameter and the lower inner diameter of the bottle body holder 700, so that the bottle body 300 is fixed in the bottle body holder 700. In one embodiment, the inner diameter of the upper end of the bottle holder 700 is preferably 24-29 mm; more preferably 25 to 28 mm; and more preferably 26 to 27mm, thereby facilitating the fixing of the bottle body and the operation. The inner diameter of the lower end of the bottle body fixing frame 700 is preferably 54-59 mm; more preferably 55 to 58 mm; and more preferably 56 to 57mm, thereby facilitating the fixing and stabilizing of the device with the base.

The base 800 is connected to the bottle holder 700, and the base 800 provides a weight balance for supporting the centrifuge tube 4 and the bottle holder 700, so as to prevent the centrifuge tube 4 from toppling over. The base 800 has a groove 801, and the outer diameter of the groove 801 is larger than the outer diameter of the lower end of the bottle body mount 700, so that the bottle body mount 700 is fixed on the base 800 through the groove 801. The base 800 may be made of metal, so that the metal has a high density to perform the weight balancing. In addition, the bottle holder 700 can be used to stably place the centrifuge tube 4, and also can be used to adjust the height of the bottom of the bottle 300 of the centrifuge tube 4 from the operating position such as the operating table or the table, that is, the height of the cork 400 from the operating position of the user. In one embodiment, the height of the soft plug 400 from the user's operating position is preferably 3 to 8 mm; more preferably 4 to 7 mm; and more preferably 5 to 6mm, so that the user can conveniently collect the centrifuged liquid through the needle.

Referring to fig. 12, it is a schematic structural view of the centrifugal tube leading-out member fixing frame of the present invention. As shown in fig. 12, the centrifuge tube 4 may further comprise a lead-out holder 600. The outer diameter of the lead-out member holder 600 is between the inner diameter of the upper end and the inner diameter of the lower end of the bottle body holder 700, so that the lead-out member holder 600 is disposed in the bottle body holder 700 for fixing the lead-out member 900. The lead-out fixture 600 includes a through hole 601 having a height h and a diameter R.

The lead-out member 900 may be connected to the lead-out member holder 600, so that the relative positions of the lead-out member holder 600 and the lead-out member 900 are controlled by controlling the height h and the diameter R of the lead-out member holder 600. In one embodiment, the height h of the through hole 601 is preferably 13-18 mm; more preferably 14 to 17 mm; and more preferably 15-16 mm, thereby facilitating the fixation of the extraction needle and the extension tube. The diameter R of the through hole 601 is preferably 4-9 mm; more preferably 5 to 8 mm; and more preferably 6 to 7mm, thereby facilitating the fixing of the extension pipe.

The lead-out 900 may include a needle 901, an extension tube 902, and a collection vial 903. The needle 901 comprises a first needle end 901a and a second needle end 901b, the first needle end 901a extends to the inside of the bottle 300, and the second needle end 901b extends to the through hole 601, so that the needle 901 penetrates the cork 400 through the through hole 601. The elongated tube 902 is hollow cylindrical and comprises a first elongated end 902a and a second elongated end 902b, the first elongated end 902a is connected to the second end 901b of the needle 901. The collection vial 903 is attached to the second elongated end 902b of the elongated tube 902. Wherein, the containing space of the bottle body 300 of the centrifuge tube 4, the needle 901, the extension tube 902 and the collection bottle 903 are spatially communicated. Furthermore, the outlet 900 may further comprise a multi-way valve, for example a three-way valve.

In one embodiment, the needle 901 penetrates the cork 400 of the centrifuge tube 4 through the through hole 601 of the guide-out holder 600, i.e. the needle 901 contacts and extracts the liquid contained in the bottle 300 of the centrifuge tube 4. Then, since the needle 901 and the extension tube 902 are connected to each other, the centrifuged liquid can flow from the needle 901 along the extension tube 902. Then, since the extension tube 902 and the collection bottle 903 are connected to each other, the centrifuged liquid can flow from the extension tube 902 into the collection bottle 903 again to be collected.

Centrifuge tube 4 may further comprise a sealing cap 100 connecting upper cap 200 and sealing injection hole 201 and air hole 202. For example, the sealing cover 100 may have a first protrusion 101 corresponding to the injection hole 201 and a second protrusion 102 corresponding to the air hole 202.

The manner of use of the centrifuge tube is described in detail below by way of example.

First, hold whole blood in the centrifuging tube, and after the centrifugation, blood divide into from top to bottom: a translucent to pale yellow upper layer of plasma, a white middle layer rich in platelets and white blood cells, and a dark red lower layer rich in red blood cells.

Case of using centrifuge tube 1:

the height of the centrifuge tube was 125mm and the spiral structure was used to move up and down. When the second end 203a2 of the extraction tube 203a is moved up to the limit, the second end 203a2 extends to 14mm from the floor 300a and is referred to as the first position, and when the second end 203a2 of the extraction tube 203a is moved down to the limit, the second end 203a2 extends to 1mm from the floor 300a and is referred to as the second position.

First, a first centrifugation is performed, followed by placing the aspiration tube 203a in the second position and extracting red blood cells. A second centrifugation is performed with the aspiration tube 203a in the first position and platelet-poor plasma (PPP) is extracted from the upper layer. The aspiration tube 203a is placed in the second position and, after mixing, platelet-rich plasma (PRP) is extracted. The centrifugal force of the first centrifugation was 2300g, which lasted 3 minutes. The centrifugal force of the second centrifugation was 3000g for 3 minutes.

Case of using centrifuge tube 2:

the height of the centrifuge tube was 125mm and the spiral structure was used to move up and down. The second end 203a2 of the extraction tube 203a extends to 1mm from the bottom surface 300a and is referred to as the second position, and the fourth end 203b2 of the auxiliary extraction tube 203b extends to 14mm from the bottom surface 300a and is referred to as the first position. The rest of the procedure was as in the case of centrifuge tube 1.

Case of using centrifuge tube 3:

the height of the centrifuge tube was 125 mm. The inner tube upper opening 205a and the outer tube upper opening 204a are both located 14mm from the bottom surface 300a and are referred to as a first position, and the inner tube lower opening 205b and the outer tube lower opening 204b are both located 1mm from the bottom surface 300a and are referred to as a second position. The rest of the procedure was as in the case of centrifuge tube 1.

Case of using centrifuge tube 4:

when using centrifuge tube 4, a shorter needle 901 is selected if the lower layer is to be collected, and a longer needle 901 than that used to collect the lower layer is selected if the middle layer is to be collected, since the length of needle 901 corresponds to the solution to be pumped. Meanwhile, a three-way valve can be further installed on the centrifugal tube 4. The first end of the three-way valve is communicated with the needle 901 and the extension tube 902; the second end of the three-way valve is in communication with the collection bottle 903; and the third end of the three-way valve is connected to the drawing device, so that the drawing force can be provided by the drawing device to draw the liquid contained in the bottle 300 of the centrifuge tube 4 into the collection bottle 903 through the needle 901 and the extension tube 902. For example, the extraction device may be a syringe or the like capable of providing an extraction force. In this case, if only the lower layer is to be collected, the interface position of different layers, for example, the interface between the dark red lower layer and the white middle layer, can be accurately known by observing the color difference transmitted through the transparent extension tube 902, so as to facilitate the user to collect only the specific liquid.

Next, the centrifugal efficiencies of centrifuge tube 1 and centrifuge tube 2 were compared with those of the commercial product as a comparative example. The commercial product is YKPRP kit. The results are shown in Table 1.

TABLE 1

As shown in table 1, the centrifuge tube of the present invention has an effective centrifugation effect.

The foregoing is by way of example only, and not limiting. All equivalent modifications and variations of the present invention without departing from the spirit and scope thereof should be considered to be covered by the claims.

While the present invention has been described in detail with reference to the preferred embodiments thereof, it should be understood that the above description should not be taken as limiting the present invention. Numerous modifications and alterations to the present invention will become apparent to those skilled in the art upon reading the foregoing description. Accordingly, the scope of the invention should be limited only by the attached claims.

Claims (12)

1. A centrifuge tube, comprising:

the bottle body is provided with an accommodating space formed by a bottom surface and a bottle wall, the lower part of the accommodating space is in an inverted circular truncated cone shape, the bottle body is provided with an upper opening, and the distance from the upper opening to the bottom surface is a height;

the upper cover is connected with the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening so as to seal the upper opening through the upper cover; and

the suction pipe comprises a first end and a second end, the first end is connected with and penetrates through the upper cover, and the second end extends into the accommodating space;

wherein the second end extends to a position 0-5 mm away from the bottom surface.

2. The centrifuge tube of claim 1, wherein the aspiration tube moves up and down in the direction of the height.

3. The centrifuge tube of claim 2, wherein the second end extends 8-20 mm from the bottom surface when the second end moves upward in the height direction to an extreme position; and when the second end moves downwards to the limit position along the height direction, the second end extends to a position 0-3 mm away from the bottom surface.

4. The centrifuge tube of claim 1, further comprising:

and the auxiliary suction pipe comprises a third end and a fourth end, the third end is connected with and penetrates through the upper cover, the fourth end extends into the accommodating space, and the auxiliary suction pipe is closer to the bottle wall than the suction pipe.

5. The centrifuge tube of claim 4, wherein the fourth end extends 8-20 mm from the bottom surface.

6. The centrifuge tube of claim 1, wherein the aspiration tube further comprises:

an inner tube having an inner tube upper opening and an inner tube lower opening, the inner tube upper opening being closer to the upper opening than the inner tube lower opening; and

the outer tube is sleeved outside the inner tube and provided with an outer tube upper opening and an outer tube lower opening, and the outer tube upper opening is closer to the upper opening than the outer tube lower opening;

the center of the upper opening of the inner pipe and the center of the lower opening of the inner pipe are straight lines along the height direction, and the center of the upper opening of the outer pipe and the center of the lower opening of the outer pipe are not straight lines along the height direction; or the center of the upper opening of the outer tube and the center of the lower opening of the outer tube are a straight line along the height direction, and the center of the upper opening of the inner tube and the center of the lower opening of the inner tube are not a straight line along the height direction.

7. A centrifuge tube, comprising:

a bottle body having a hollow cylindrical shape and having an upper opening and a lower opening;

the upper cover is connected with the upper part of the bottle body, and the inner diameter of the lower end surface of the upper cover corresponds to the outer diameter of the upper opening so as to seal the upper opening through the upper cover; and

the soft plug is connected with the lower part of the bottle body and is provided with a plurality of soft plug sealing rings positioned on the peripheral surface of the soft plug, and the outer diameter of the upper end surface of the soft plug corresponds to the inner diameter of the lower opening so as to seal the lower opening through the soft plug;

wherein, the soft plug is used for puncturing a hole-forming elastomer.

8. The centrifuge tube of claim 7, further comprising:

the lower cover is connected with the lower part of the bottle body and provided with a plurality of lower cover sealing rings positioned on the upper part of the lower cover, the lower cover is in an inverted round table shape, the outer diameter of the upper end surface of the lower cover is larger than that of the lower end surface of the lower cover, and the outer diameter of the upper end surface of the lower cover corresponds to the inner diameter of the bottle body.

9. The centrifuge tube of claim 7, further comprising:

the bottle body fixing frame is provided with a containing space for containing the bottle body, the bottle body fixing frame is provided with an upper end inner diameter and a lower end inner diameter, the upper end inner diameter is smaller than the lower end inner diameter, the inner diameter of the bottle body fixing frame is gradually increased from the upper end inner diameter to the lower end inner diameter, and the outer diameter of the bottle body is between the upper end inner diameter and the lower end inner diameter; and

the base is connected with the bottle body fixing frame and is provided with a groove, and the outer diameter of the groove corresponds to the outer diameter of the lower end of the bottle body fixing frame, so that the bottle body fixing frame is fixed on the base through the groove.

10. The centrifuge tube of claim 9, further comprising:

and the leading-out part fixing frame is arranged in the bottle body fixing frame and comprises a through hole, and the outer diameter of the leading-out part fixing frame is between the inner diameter of the upper end and the inner diameter of the lower end of the bottle body fixing frame.

11. The centrifuge tube of claim 10, further comprising:

the derivation piece is connected the derivation piece mount, just the derivation piece contains:

a needle head comprising a first needle end and a second needle end, the first needle end extending into the bottle body and the second needle end extending to the through hole such that the needle head pierces the soft plug through the through hole;

the extension tube is hollow cylindrical and comprises a first extension end and a second extension end, and the first extension end is connected with the second needle end of the needle head; and

a collection bottle connected to the second elongated end of the elongated tube;

wherein the bottle body, the needle, the extension tube and the collection bottle are spatially communicated.

12. The centrifuge tube of claim 9, further comprising:

an injection hole which is arranged on the upper cover and penetrates through the upper cover;

the air hole is arranged on the upper cover and penetrates through the upper cover; and

the sealing cover is connected with the upper cover and comprises a first convex part corresponding to the injection hole and a second convex part corresponding to the air hole so that the sealing cover can seal the injection hole and the air hole;

wherein the inner diameter of the injection hole is larger than that of the air hole.

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