CN104931316B - Cell preserves centrifugal filter device - Google Patents
Cell preserves centrifugal filter device Download PDFInfo
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- CN104931316B CN104931316B CN201510311845.7A CN201510311845A CN104931316B CN 104931316 B CN104931316 B CN 104931316B CN 201510311845 A CN201510311845 A CN 201510311845A CN 104931316 B CN104931316 B CN 104931316B
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- hollow pipe
- transparent column
- conduit
- column hollow
- bottom cover
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Abstract
The invention discloses a kind of cell centrifugal filtration apparatus for placing, include transparent column hollow pipe, the upper inner of the transparent column hollow pipe crosses filter equipped with funnelform, the bottom of the mistake filter is equipped with conduit, strainer is equipped between the conduit and mistake filter, the bottom thread of the transparent column hollow pipe is connected with bottom cover, the upper surface of the bottom cover is equipped with support column, the side of the transparent column hollow pipe offers arc groove, glass slide is inserted into transparent column hollow pipe pipe by arc groove, it is simple in structure, it is vdiverse in function, effectively improve work efficiency, reduce consumptive material, it is cost-effective, it can prevent confusion, reduce cross contamination possibility.
Description
Technical field
The present invention relates to cell detection apparatus field, more particularly to a kind of cell to preserve centrifugal filter device.
Background technology
During liquid based cytology technology film-making, it is necessary to use sample when carrying out centrifugal filtration to cell and settling film-making
The a variety of instrument and equipments and dress such as this transfer, pelleter, liquid relief syringe, centrifuge tube, preparation bin (or film-making folder), glass slide
Put, cost is higher, and in operating process, sample needs manually to shift or be loaded between multiple instrument and equipments, and process is cumbersome, and process is superfluous
It is long；And when more parts of cell samples are shifted and are loaded, the reverse entanglement cross contamination easily occurred in manual operation shows
As seriously affecting the accuracy of cell detection；Sample is easily lost and pollutes people, thing and environment in transfer process, causes
The rate of missed diagnosis of cell detection increases, and bio-safety endangers hidden danger increase.
The content of the invention
The object of the present invention is to provide a kind of cell to preserve centrifugal filter device, vdiverse in function, effectively improves work efficiency,
Consumptive material is reduced, it is cost-effective, operation is simplified, prevents cross contamination.
In order to solve the problems existing in background technology, the present invention uses following technical scheme：
Cell preserves centrifugal filter device, includes transparent column hollow pipe, the top of the transparent column hollow pipe
Inner side is equipped with funnelform filter excessively, and the bottom of the mistake filter is equipped with conduit, is equipped between the conduit and excessively filter
Strainer, the bottom thread of the transparent column hollow pipe are connected with bottom cover, and the upper surface of the bottom cover is equipped with support column, institute
The side for the transparent column hollow pipe stated offers arc groove, and glass slide is inserted into transparent column hollow pipe pipe by arc groove,
The transparent column hollow pipe is equipped with head cover.
Both sides are respectively provided with a hanging column at upper 1/3 on the outside of the transparent column hollow pipe, easy to hang over turning for centrifuge
On disk.
The head cover is spiral to be connected on transparent column hollow pipe, after clinician completes to draw materials, is unscrewed head cover, is put
Enter and sample brush head, then screw, so that the present invention has cell preservation effect.
The bottom inside of the transparent column hollow pipe is equipped with internal thread, and the bottom cover is equipped with external screw thread, bottom cover
Be threadedly coupled with transparent column hollow pipe, bottom cover can by threaded adjusting, adjust bottom cover on support column and conduit between away from
From so that glass slide can be supported column support so that glass slide can be close to the bottom of conduit, when need to take glass slide
When lower, only bottom cover need to be unscrewed so that glass slide is separated with conduit, and glass slide is taken out from arc groove, can be on glass slide
The cell of sedimentation is detected.
The lower edge of the conduit is coated with rubber cushion so that glass slide is tight with catheter contact, prevent leakage.
The diameter of the support column is more slightly larger than conduit diameter and surface is covered with a thin layer rubber cushion, is being not inserted into glass slide
When, screw bottom cover so that support column just blocks the lower mouth of conduit, to prevent pipe inner cell sample liquid from leaking out.
The upper groove surface horizontal direction of the arc groove at grade, facilitates the fixation of glass slide with conduit bottom.
The bottom surface of the bottom cover is arc shape so that device is merely able to put upside down, just can so make to hold when placing
Cell in hollow pipe preserves treatment fluid and was back in filter, and submergence was placed on the sampling brush head in filter, ensured to take
The sample energy liquid to be treated useful effect that sample paints.
Beneficial effect of the present invention：The configuration of the present invention is simple, it is vdiverse in function, work efficiency is effectively improved, reduces consumptive material, is saved
Cost, simplifies operation, prevents in detection and bio-safety caused by the leakage of sample liquid endangers after detection, intersection is dirty between avoiding sample
Dye, improves detection accuracy.
Brief description of the drawings
Fig. 1 is principle of the invention structure diagram；
Fig. 2 is planar structure schematic diagram of the present invention；
Fig. 3 is planar structure schematic diagram of the present invention.
Embodiment
The embodiment of the present invention is illustrated below in conjunction with the accompanying drawings：
Cell preserves centrifugal filter device, includes transparent column hollow pipe 1, the transparent column hollow pipe 1 it is upper
Be equipped with the inside of portion it is funnelform cross filter 2, the bottom of the mistakes filter 2 is equipped with conduit 3, the conduit 3 and filter 2 it
Between be equipped with strainer 4, the bottom thread of the transparent column hollow pipe 1 is connected with bottom cover 5, and the upper surface of the bottom cover 5 is set
There is support column 6, the side of the transparent column hollow pipe 1 offers arc groove 7, and glass slide 8 is inserted into transparent by arc groove 7
In cylinder hollow pipe 1 is managed, the transparent column hollow pipe 1 is equipped with head cover 13.
The bottom inside of the transparent column hollow pipe 1 is equipped with internal thread 9, and the bottom cover 5 is equipped with external screw thread 10,
Bottom cover 5 is threadedly coupled with transparent column hollow pipe 1, and bottom cover 5 can adjust support column 6 and conduit on bottom cover 5 by threaded adjusting
The distance between 3, supported so that glass slide 8 can be supported column 6 so that glass slide 8 can be close to the bottom of conduit 3,
When glass slide 8 need to be removed, knob bottom cover 5 is only needed so that glass slide 8 is separated with conduit 3, by glass slide 8 from arc groove 7
Take out, the cell deposited on glass slide 8 can be detected.
Both sides are respectively provided with a hanging column 12 at the outside of transparent column hollow pipe 1 upper 1/3, easy to hang over centrifuge
On turntable.
The head cover 13 is spiral to be connected on transparent column hollow pipe 1, after clinician completes to draw materials, unscrews head cover
13, sampling brush head is put into, then screw, so that the present invention has cell preservation effect.
The upper groove surface horizontal direction of the arc groove 7 at grade, facilitates consolidating for glass slide 8 with 3 bottom of conduit
It is fixed.
The lower edge of the conduit 3 is coated with rubber cushion 11 so that glass slide 8 contacts tightly with conduit 3, prevent leakage.
The diameter of the support column 6 is more slightly larger than 3 diameter of conduit and surface is covered with a thin layer rubber cushion 11, is being not inserted into load glass
During piece 8, bottom cover 5 is screwed so that support column 6 just blocks the lower mouth of conduit 3, to prevent pipe inner cell sample liquid from leaking out.
The bottom surface of the bottom cover 5 is arc shape so that device is merely able to put upside down, just can so make Sheng when placing
The cell treatment fluid being placed in conduit 3 was back in filter 2, and submergence was placed on the sampling brush head in filter 2, ensured sampling
The sample energy liquid to be treated useful effect painted.
In the use of the present invention, the sampling brush head for speckling with cell sample was inserted in filter 2, the present apparatus is inverted so that
The cell of prepackage preserves treatment fluid submergence sampling brush head for a period of time in bottle, unscrews bottom cover 5, Density Separation is added into conduit 3
After liquid, in insertion glass slide 8 to arc groove 7 and bottom cover 5 is tightened, the present apparatus is hung on the turntable of centrifuge and is centrifuged,
After the filtered screening with density centrifugation of sample, fragment of tissue is filtered by strainer 4, and cell enters close in conduit 3 through strainer 4
Spend in separating liquid, under the collective effect of centrifugal force and buoyancy, cell is deposited to load by screening, the big sick cell of density
On slide 8 and it is coated with the glass slide 8 of cationic membrane and firmly attracts, and the small mucilaginous substance of density and inflammatory cell is still most
It is suspended in sample rate liquid.After centrifugation, inverted device, unscrews bottom cover 5, takes out glass slide 8 and to thin on glass slide 8
Born of the same parents are detected, then screw bottom cover 5, and the liquid leakage pollution environment in anti-locking apparatus, causes bio-safety to endanger.Present apparatus collection
Filtering, centrifugation, cell settlement are integrated, vdiverse in function, avoid the process that sample shifts back and forth, reduce operating procedure, section
Detection time has been saved, has effectively improved work efficiency, and has reduced consumptive material, it is cost-effective, prevent pollution environment and bio-safety harm,
Avoid cross contamination between sample.
Using above-mentioned foundation the embodiment of the present invention as enlightenment, by above-mentioned description, relevant staff safely may be used
In the range of without departing from the technology of the present invention thought, to carry out various change and modification.The technical scope of the present invention is not
The content being confined on specification, it is necessary to which its technical scope is determined according to right.
Claims (5)
1. cell preserves centrifugal filter device, include transparent column hollow pipe, it is characterised in that：The transparent column is hollow
The upper inner of pipe crosses filter equipped with funnelform, and the bottom of the mistake filter is equipped with conduit, and the conduit is with crossing filter
Between be equipped with strainer, the bottom thread of the transparent column hollow pipe is connected with bottom cover, the transparent column hollow pipe
Bottom inside is equipped with internal thread, and the bottom cover is equipped with external screw thread, and bottom cover is threadedly coupled with transparent column hollow pipe, described
The upper surface of bottom cover is equipped with support column, and the side of the transparent column hollow pipe offers arc groove, and glass slide passes through circular arc
In groove insertion transparent column hollow pipe pipe, the transparent column hollow pipe is equipped with head cover.
2. cell according to claim 1 preserves centrifugal filter device, it is characterised in that：The lower edge of the conduit is coated with
Rubber cushion.
3. cell according to claim 1 preserves centrifugal filter device, it is characterised in that：The diameter ratio of the support column
Conduit diameter is slightly larger and surface is covered with a thin layer rubber cushion.
4. cell according to claim 1 preserves centrifugal filter device, it is characterised in that：The upper groove surface of the arc groove
Horizontal direction and conduit bottom are at grade.
5. cell according to claim 1 preserves centrifugal filter device, it is characterised in that：The bottom surface of the bottom cover is arc
Shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510311845.7A CN104931316B (en) | 2015-06-08 | 2015-06-08 | Cell preserves centrifugal filter device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510311845.7A CN104931316B (en) | 2015-06-08 | 2015-06-08 | Cell preserves centrifugal filter device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104931316A CN104931316A (en) | 2015-09-23 |
| CN104931316B true CN104931316B (en) | 2018-05-04 |
Family
ID=54118589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510311845.7A Active CN104931316B (en) | 2015-06-08 | 2015-06-08 | Cell preserves centrifugal filter device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104931316B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106680061B (en) * | 2016-12-23 | 2020-03-13 | 中山大学 | Parasite egg detection device and method |
| CN111051847A (en) * | 2017-07-20 | 2020-04-21 | 贝克顿·迪金森公司 | Manual method of depositing samples directly onto slides for liquid-based cytology |
| CN109520800B (en) * | 2018-11-27 | 2020-10-27 | 永康市久久科技有限公司 | Liquid-based thin-layer cell slide making clamp |
| CN116439232B (en) * | 2023-06-14 | 2023-09-29 | 山东第一医科大学附属省立医院(山东省立医院) | Chest surgery pathological tissue collecting and preserving device |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102539211A (en) * | 2012-01-09 | 2012-07-04 | 广州三瑞医疗器械有限公司 | Device and method for making liquid-based cytological smear in one step |
| CN202471474U (en) * | 2011-12-02 | 2012-10-03 | 孝感奥华医疗科技有限公司 | Slide making clamp for cell slide maker |
| CN203396630U (en) * | 2013-08-30 | 2014-01-15 | 杨晓斌 | Medical tablet preparing device |
| CN103616267A (en) * | 2013-11-13 | 2014-03-05 | 厦门宝太生物科技有限公司 | Integrated type cell sedimentation and smearing device and method for settling cell and preparing cell smear |
| CN203606191U (en) * | 2013-11-26 | 2014-05-21 | 上海宇度医学科技股份有限公司 | Thin-layer liquid-based cell slide maker |
-
2015
- 2015-06-08 CN CN201510311845.7A patent/CN104931316B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202471474U (en) * | 2011-12-02 | 2012-10-03 | 孝感奥华医疗科技有限公司 | Slide making clamp for cell slide maker |
| CN102539211A (en) * | 2012-01-09 | 2012-07-04 | 广州三瑞医疗器械有限公司 | Device and method for making liquid-based cytological smear in one step |
| CN203396630U (en) * | 2013-08-30 | 2014-01-15 | 杨晓斌 | Medical tablet preparing device |
| CN103616267A (en) * | 2013-11-13 | 2014-03-05 | 厦门宝太生物科技有限公司 | Integrated type cell sedimentation and smearing device and method for settling cell and preparing cell smear |
| CN203606191U (en) * | 2013-11-26 | 2014-05-21 | 上海宇度医学科技股份有限公司 | Thin-layer liquid-based cell slide maker |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104931316A (en) | 2015-09-23 |
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Effective date of registration: 20200103 Address after: Jiangning District of Nanjing City, Jiangsu province 210000 streets moling Road No. 12 mo Zhou Patentee after: Jiangsu informed Intellectual Property Service Co., Ltd. Address before: Lu'an City, Anhui province 237000 Yuan District of Pingqiao Industrial Park Patentee before: ANHUI HONGRUI BIOTECHNOLOGY CO., LTD. |
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Effective date of registration: 20200722 Address after: Room 214, 2 / F, building 1, 1111, Zhongshan North 1st Road, Hongkou District, Shanghai 200080 Patentee after: Hongzhijun Biotechnology (Shanghai) Co., Ltd Address before: Jiangning District of Nanjing City, Jiangsu province 210000 streets moling Road No. 12 mo Zhou Patentee before: JIANGSU ZHIJU INTELLECTUAL PROPERTY SERVICE Co.,Ltd. |