CN212491694U - Pleural effusion sediment separation bottle - Google Patents

Abstract

The utility model relates to a pleural effusion and ascites sedimentation and separation bottle, which comprises a storage part for containing pleural effusion and ascites, wherein the storage part is provided with an internal cavity for containing pleural effusion and ascites, the upper part of the storage part is provided with a liquid inlet for loading pleural effusion and a sealing part for detachably sealing the liquid inlet, the bottom of the storage part is provided with a sample discharge port for discharging target cells and a control part for controlling the opening/sealing of the sample discharge port, the side surface of the lower part of the storage part is provided with a liquid discharge port for discharging supernatant and an adjusting part for controlling the on/off of the liquid discharge port, and the liquid inlet, the sample discharge port and the liquid discharge port are respectively communicated with the internal cavity; the sedimentation separation bottle has simple and compact structure, is convenient for collecting, storing and transferring the hydrothorax and ascites, can conveniently and safely process supernatant fluid while fully retaining cell suspension and/or sediment, and avoids the biological safety problem caused by random discharge.

Description

Pleural effusion sediment separation bottle

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to pleural effusion sedimentation and separation bottle.

Background

The examination of hydrothorax and ascites is used for examining the property of hydrothorax and ascites clinically so as to determine the cause and etiology of hydrothorax and ascites formation and play an instructive role in treating clinical diseases. The etiology of the disease is many, such as cardiovascular disease, liver disease, peritoneum disease, kidney disease, nutrition disorder disease, malignant tumor, pleuroperitoneal cavity metastasis, primary tumor of pleuroperitoneal cavity, connective tissue disease, etc. The pleural and peritoneal fluid can be formed by the diseases with too much hydrops in the pleural and peritoneal cavities, and the hydrops can be divided into effusion and effusion according to the nature.

In clinic, the pleuroperitoneal fluid of a patient is usually collected and examined for cytopathology examination, however, the prior art lacks a container specially used for collecting and storing pleuroposterior fluid, so that the prior pleuroposterior fluid collecting container is eight-door, the used transfusion glass bottle is used for collecting pleuroposterior fluid, the mineral water bottle is used for collecting pleuroposterior fluid, and the like are used for collecting pleuroposterior fluid; besides tumor cells, a plurality of pathogenic bacteria and virus microorganisms can be contained in the pleural effusion and the peritoneal fluid, and the pleural effusion and the peritoneal fluid are collected by adopting the container, so that not only is the potential biological safety hazard existed, but also the container can not achieve sterility, and the cells to be detected are easy to degenerate, thereby influencing the subsequent detection and diagnosis; after the specimen reaches a pathology department, standing is needed, sediments (namely target cells) are taken out for cytological detection, the existing container is adopted for collecting hydrothorax and ascites, when the sediments in the container are taken out, supernate in the container needs to be poured repeatedly, in the process, the sediments (namely the target cells) which are originally precipitated are lifted while being poured, are mixed with the supernate and are finally poured out, important cell components are lost, and subsequent detection and diagnosis are seriously influenced; in addition, the supernatant separated from the collected pleural and peritoneal fluid is usually directly poured out, and since the supernatant inevitably contains the components of body fluid of the patient, which may include various microorganisms such as tuberculosis and viruses, the supernatant is treated in such a way, which inevitably has a biological safety hazard, and the prior art does not provide any effective technical means to solve the problem.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to improve the not enough that exists among the prior art, provide a simple structure, compactness, be used for collecting specially, save and separate the precipitation separation bottle of ascites and chest, not only be convenient for collect cell suspension and/or precipitate, moreover can be convenient, safe processing supernatant, avoid discharging the biological safety problem that causes at will.

The utility model provides a technical scheme that its technical problem adopted is:

the utility model provides a pleuroperitoneal fluid sedimentation and separation bottle, includes the storage part that is used for holding pleuroperitoneal fluid, the storage part is provided with the inside cavity that is used for holding pleuroperitoneal fluid, and the upper portion of storage part is provided with the inlet that is used for packing into pleuroperitoneal fluid and is used for dismantling to seal the sealing member of inlet, and the bottom of storage part is provided with the stock layout mouth that is used for discharging the target cell and is used for controlling stock layout mouth opens/confined control piece, and the side of storage part lower part is provided with the leakage fluid dram that is used for discharging the supernatant and is used for controlling the regulating part that the leakage fluid dram switches on/breaks off, inlet, stock layout. When the sedimentation separation bottle is used, the collected ascites and pleural fluid can be added into the inner cavity of the storage part through the liquid inlet and is sealed by the sealing part, so that the ascites and pleural fluid can be conveniently stored, and the ascites and pleural fluid can be prevented from being polluted; after the sedimentation separation bottle is conveyed to a pathology department, cell suspension and/or sediment (namely target cells) in the pleural and abdominal water can be automatically deposited at the bottom of the sedimentation separation bottle by standing the sedimentation separation bottle, and after standing for a specified time, the adjusting part is opened, so that the supernatant can be conveniently discharged from the liquid discharge port under the condition of not inclining or overturning the sedimentation separation bottle, and the cell suspension and/or the sediment are kept at the bottom of the inner cavity and cannot be discharged along with the inclination or the overturning of the sedimentation separation bottle; finally, the liquid inlet can be conveniently opened through the control part, so that the cell suspension and/or the precipitate can be conveniently taken out of the precipitation separation bottle, and cytology detection can be conveniently carried out; therefore, the sediment separation bottle is convenient for collecting, storing and transferring the hydrothorax and ascites fluid, and can conveniently remove the upper cleaning fluid while fully retaining the cell suspension and/or the sediment, so that the upper cleaning fluid is separated from the target cells, and the cell suspension and/or the sediment can be conveniently collected for cytological detection.

In one scheme, the storage part comprises a bottle body, the liquid inlet is arranged on the upper portion of the bottle body, a necking part with the inner diameter gradually reduced is arranged at the lower end of the bottle body, the stock layout port is arranged at the lower end of the necking part, a base used for supporting the bottle body is arranged on the outer side of the necking part, and the liquid outlet is arranged in the bottle body or the necking part. The bottle body can be stably placed on a table top by arranging the base, and the necking part is arranged to be beneficial to enriching the cell suspension and/or the sediment in the necking part and finally discharging the sediment separation bottle from the necking part.

In one scheme, the base is of a cylindrical structure. Such as a cylinder, a conical barrel configuration, etc.

In another scheme, the base comprises at least three support sheets, the support sheets are distributed along the circumferential direction of the bottle body respectively, the upper ends of the support sheets are connected with the bottle body or the necking part respectively, and the support sheets are used for supporting the bottle body. Not only is the bottle body convenient to be stably placed on the desktop, but also the user can conveniently operate the control piece through the gap between the two support pieces, and the bottle body is more convenient to use.

In order to facilitate the smooth taking out of the large-volume sediments from the bottle body, the necking part is detachably fixed at the lower end of the bottle body, and the liquid outlet is arranged at the necking part. Adopt detachable mode to connect necking down portion and bottle, the separation of the necking down portion of being convenient for and bottle not only can be convenient separate the bottle alone to can be convenient take out the great precipitate of volume from the upper end of necking down portion.

Preferably, the regulating part is a valve.

In order to realize detachable connection, preferably, the lower end of the bottle body is provided with an external thread, and the upper end of the necking part is provided with an internal thread matched with the external thread. The detachable connection is realized through the matching of the external thread and the internal thread.

Preferably, the sealing member is a rubber plug, or the sealing member is a sealing cover, the sealing cover is provided with a threaded hole, the threaded hole is provided with an internal thread, and the liquid inlet is provided with an external thread matched with the internal thread. Not only can realize sealing, but also can realize detachable connection, and is more convenient to use.

In order to discharge the cell suspension and/or sediment at the bottom of the inner cavity, the control member further comprises a bottom cover, and the bottom cover is detachably fixed at the sample discharge port. In use, the user can open the sample outlet by opening the bottom cover to allow the cell suspension and/or sediment to be discharged.

To the condition that only the precipitate is needed, further, the bottom cover is further provided with a communicating port, the communicating port is provided with a communicating pipe, and the communicating pipe is provided with a valve. When the sediment at the bottom of the sediment separation bottle needs to be taken out, the valve can be opened firstly, liquid around the sediment is discharged by the communicating port, then the valve is closed, and then the bottom cover is opened, so that the sediment with less water content can be obtained, and the subsequent detection and diagnosis are more convenient.

Furthermore, the lower end face of the communicating pipe is of an inclined structure. So as to play a role of drainage in the process of transferring sediment and/or suspension, and is beneficial to more convenient operation.

Preferably, the lower end of the necking part is provided with an external thread, and the bottom cover is provided with an internal thread matched with the external thread; or the lower end of the necking part is provided with a clamping groove, the bottom cover is provided with a buckle matched with the clamping groove, and the stock layout port is sealed through the matching of the buckle and the clamping groove. So as to control the opening and closing of the discharge port.

Preferably, the storage part is made of transparent material.

Preferably, the storage part is made of glass or plastic.

For convenience of metering, preferably, a scale line is provided along the height direction of the bottle body.

In order to hang the precipitation separation bottle, the precipitation separation bottle further comprises a hanging part which is arranged on the sealing element or the bottle body and used for hanging. When taking out the cell suspension and/or sediment in the sediment separation bottle, a user can hang the sediment separation bottle on the bracket by using the hanging part, thereby being convenient for taking out the cell suspension and/or sediment from the lower sample outlet.

In order to conveniently and safely process the supernatant after sedimentation, a recovery part for storing the supernatant is further arranged outside the necking part, the recovery part is provided with a closed storage cavity, and the volume of the storage cavity is greater than or equal to that of the internal cavity and is used for storing the supernatant;

an annular bulge is arranged on the side face of the bottle body, first lock catches are respectively arranged on two sides of the annular bulge, a first connecting hole is further formed in the annular bulge, the first connecting hole is located between the two first lock catches, an annular groove is formed in the outer side of the pair of the annular bulges, an annular sealing ring is fixed in the annular groove, a communicating opening is formed in the annular sealing ring, and the communicating opening is communicated with the first connecting hole;

the recycling portion is of an annular structure, two second lock catches respectively matched with the first lock catches are arranged on the inner side of the recycling portion, the adjusting portion is a second communicating hole formed between the two second lock catches, the second communicating hole is communicated with the storage cavity, the recycling portion is movably connected to the annular protrusion through the matching of the second lock catches and the first lock catches, and the annular sealing ring is enabled to be in a compression state along the radial direction. Not only can reach the effect of pressure seal, can also through rotate the recovery part adjust the second intercommunicating pore with the relative position of intercommunication mouth, when the second intercommunicating pore rotate with when the corresponding position department of intercommunication mouth, the two intercommunication to make the bottle can communicate with recovery part, so that the supernatant of bottle can be under the effect of gravity in the automatic recovery part that flows in, reach and deposit the supernatant, avoid the purpose of discharging at will, then only need suitably rotate the recovery part, make second intercommunicating pore and intercommunication mouth take place the dislocation, can reach the purpose of sealed recovery part, thereby avoid the supernatant to flow out the recovery part.

Preferably, the first lock catch is an annular fixture block arranged on the upper side and the lower side of the annular protrusion, the second lock catch is an annular catch with an L-shaped cross section, and the annular catch is matched with the annular fixture block. Not only can realize the fixed of recovery portion, make the recovery portion rotate for the bottle under the effect of external force moreover to realize swing joint.

In order to facilitate separation of the necking part and the bottle body, the bottle further comprises an annular connector, the lower end of the bottle body is provided with an external thread or an internal thread, the annular connector is provided with an internal thread or an external thread matched with the external thread or the internal thread, and the annular protrusion is arranged on the annular connector.

For avoiding connecting the in-process of necking down portion and bottle, the portion of retrieving may rotate for the necking down portion to the problem of unable screw up necking down portion and bottle, in further scheme, the lateral surface of cyclic annular connector still is provided with first dog, the portion of retrieving be provided with the second dog of first dog looks adaptation, the cooperation through first dog and second dog restriction portion of retrieving can only be for cyclic annular connector rotatory round. Namely, make first dog and second dog can interfere each other to reach spacing purpose, the second dog can only rotate the round relative to necking portion under the drive of recovery portion, and in this process, the second intercommunicating pore with the intercommunication mouth can coincide once, so that realize the intercommunication.

Compared with the prior art, use the utility model provides a pair of pleural effusion sedimentation and separation bottle has following beneficial effect:

1. the sediment separation bottle is convenient for collecting, storing and transferring the hydrothorax and ascites fluid, and can conveniently remove the upper cleaning fluid while fully retaining the cell suspension and/or the sediment, so that the upper cleaning fluid is separated from the target cells, and the cell suspension and/or the sediment can be conveniently collected for cytological detection.

2. The sedimentation separation bottle has simple and compact structure, is convenient to use, and can effectively avoid the biosafety problem caused by random discharge.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

Fig. 1 is a schematic structural view of a pleural effusion fluid precipitation separation flask provided in embodiment 1 of the present invention.

Fig. 2 is a bottom view of fig. 1.

Fig. 3 is a partial cross-sectional view of fig. 1.

Fig. 4 is a schematic structural diagram of another pleural and peritoneal fluid sedimentation separation bottle provided in embodiment 1 of the present invention.

Fig. 5 is a schematic view of a partial structure of a pleural effusion fluid precipitation separation bottle provided in embodiment 1 of the present invention.

Fig. 6 is a schematic structural view of a pleural effusion fluid precipitation separation flask provided in embodiment 1 of the present invention.

Fig. 7 is a schematic structural view of a pleural effusion fluid precipitation separation flask provided in embodiment 2 of the present invention.

Fig. 8 is a schematic structural view of a pleural effusion fluid precipitation separation flask provided in embodiment 3 of the present invention.

FIG. 9 is a partial sectional view of FIG. 8, in which the bottle body and the recovery part are in a state of communication.

FIG. 10 is a partial sectional view of FIG. 8, in which the bottle body and the recovery part are not in communication with each other.

Description of the drawings

A vial 101, a liquid inlet 102, a seal 103, a necked-down portion 104, a sample outlet 105, a control member 106, a liquid outlet 107, a valve 108, a base 109, a support plate 110, a graduation mark 111, an annular boss 112, an internal cavity 113, external threads 114, a screw thread, a,

Bottom cover 201, communication pipe 202,

A collection part 301, a storage cavity 302, a second communication hole 303, a second lock 304, a second stopper 305,

The connecting structure comprises an annular connector 401, internal threads 402, a first connecting hole 403, an annular sealing ring 404, a communication port 405, a first stop 406 and a first lock 407.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiment of the present invention, all other embodiments obtained by the person skilled in the art without creative work belong to the protection scope of the present invention.

Example 1

Referring to fig. 1-3, in the present embodiment, a pleural effusion and ascites sedimentation and separation bottle is provided, which includes a storage portion for containing pleural effusion and ascites, the storage portion is provided with an internal cavity 113 for containing pleural effusion and ascites, the upper portion of the storage portion is provided with a fluid inlet 102 for loading pleural effusion and a sealing member 103 for detachably sealing the fluid inlet 102, the bottom of the storage portion is provided with a sample discharge port 105 for discharging target cells and a control member 106 for controlling the opening/closing of the sample discharge port 105, the side surface of the lower portion of the storage portion is provided with a fluid outlet 107 for discharging supernatant and an adjustment portion for controlling the opening/closing of the fluid outlet 107, in the present embodiment, the adjustment portion preferably employs a valve 108, and the fluid inlet 102, the sample discharge port 105 and the fluid outlet 107 are respectively communicated with the internal cavity 113, as shown in fig. 3.

When the sediment separation bottle is used, the collected ascites and pleural fluid can be added into the inner cavity 113 of the storage part through the liquid inlet 102 and sealed by the sealing element 103, so that the ascites and pleural fluid can be conveniently stored, and the ascites and pleural fluid can be prevented from being polluted; when the sedimentation separation bottle is conveyed to a pathology department, the cell suspension and/or sediment (namely target cells) in the pleural and abdominal water can be automatically deposited at the bottom of the sedimentation separation bottle by standing the sedimentation separation bottle, and when the sedimentation separation bottle is standing for a specified time, the adjusting part is opened, so that the supernatant can be conveniently discharged from the liquid discharge port 107 under the condition that the sedimentation separation bottle is not inclined or turned over, and the cell suspension and/or sediment are kept at the bottom of the internal cavity 113 and cannot be discharged along with the inclination or turning over of the sedimentation separation bottle; finally, the liquid inlet 102 may be conveniently opened by the control member 106 so that the cell suspension and/or pellet may be conveniently removed from the present pellet separation vial for cytological testing. The sediment separation bottle is convenient for collecting, storing and transferring hydrothorax and ascites, and can conveniently remove the upper cleaning liquid while fully retaining the cell suspension and/or sediment, so that the upper cleaning liquid is separated from the target cells, and the cell suspension and/or sediment can be conveniently collected for cytological detection.

As shown in fig. 2 and 3, in one embodiment of the present invention, the storage portion includes a bottle body 101, the liquid inlet 102 is disposed at an upper portion of the bottle body 101, a necking portion 104 with a gradually decreasing inner diameter is disposed at a lower end of the bottle body 101, the sample outlet 105 is disposed at a lower end of the necking portion 104, a base 109 for supporting the bottle body 101 is disposed at an outer side of the necking portion 104, and the liquid outlet 107 is disposed at the bottle body 101 or the necking portion 104. The bottle body 101 can be stably placed on a table by arranging the base 109, and the constriction 104 can be arranged to facilitate the enrichment of the cell suspension and/or sediment in the constriction 104, and finally the sediment separation bottle can be discharged from the constriction 104.

The base 109 may have various embodiments, and as shown in fig. 2 and 3, for example, the base 109 has a cylindrical structure, such as a cylinder, a cone, and the like. For convenience of operation, as another example, as shown in fig. 4, the base 109 includes at least three support sheets 110, the support sheets 110 are respectively disposed along the circumferential direction of the bottle bodies 101, the upper ends of the support sheets 110 are respectively connected to the bottle bodies 101 or the necked portions 104, and the support sheets 110 are used for supporting the bottle bodies 101; not only is the bottle body 101 convenient to be stably placed on a table top, but also the user can operate the control member 106 through the gap between the two support sheets 110, which is beneficial to more convenient use.

The sealing member 103 has various embodiments, and as an embodiment, the sealing member 103 may be a rubber plug, and when in use, the rubber plug is pressed into the liquid inlet 102 to seal the liquid inlet 102; as another embodiment, the sealing element 103 may be a sealing cover, the sealing cover is provided with a threaded hole, the threaded hole is provided with an internal thread, and the liquid inlet 102 is provided with an external thread adapted to the internal thread, so that sealing and detachable connection can be realized, and the use is more convenient; it can be understood that the sealing member 103 may also be a sealing cover, the sealing cover is provided with a buckle, the liquid inlet 102 is provided with a clamping groove, and the sealing of the liquid inlet 102 is realized through the matching of the buckle and the clamping groove, and the principle is like a music buckle, which is not described herein again.

To facilitate the discharge of the cell suspension and/or sediment from the bottom of the internal cavity 113, in an embodiment, the control member 106 includes a bottom cover 201, and the bottom cover 201 is detachably fixed to the discharge port 105, so that in use, a user can open the discharge port 105 by opening the bottom cover 201 to discharge the cell suspension and/or sediment. Similarly, the bottom cover 201 has various embodiments, as an example, the lower end of the necking portion 104 is provided with an external thread, the bottom cover 201 is provided with an internal thread adapted to the external thread, and the sample discharge port 105 is detachably closed by the matching of the external thread and the internal thread, as shown in fig. 2 and 3, as another example, the lower end of the necking portion 104 is provided with a clamping groove, the bottom cover 201 is provided with a buckle adapted to the clamping groove, and the sample discharge port 105 can be closed by the matching of the buckle and the clamping groove, which is not described herein again.

Preferably, in the present embodiment, the storage part is made of a transparent material, for example, the storage part may be made of glass or plastic. For the convenience of metering, a graduation mark 111 is further provided along the height direction of the bottle body 101, as shown in fig. 3.

In this embodiment, since the sample discharge port 105 is disposed at the lower end of the whole sedimentation and separation bottle, there is usually a problem that it is inconvenient to operate when taking out the cell suspension and/or the sediment, in a further aspect, the sedimentation and separation bottle further comprises a hanging portion disposed at the sealing member 103 or the bottle body 101 for hanging, so that when taking out the cell suspension and/or the sediment in the sedimentation and separation bottle, a user can hang the sedimentation and separation bottle on the bracket by using the hanging portion, thereby taking out the cell suspension and/or the sediment from the sample discharge port 105 below.

As an example, the hanging part may be a pull ring, and both ends of the pull ring are movably connected to the sealing member 103 or the bottle 101 so as to be hung on a bracket; as another example, the hanging portion may be an annular boss 112 disposed along the circumferential direction of the bottle 101, and as shown in FIG. 5, the bottle 101 may be clamped on the support by the annular boss 112, so as to achieve the hanging purpose.

Example 2

In order to facilitate the smooth removal of the large-volume sediment from the bottle 101, the main difference between the present embodiment 2 and the above embodiment 1 is that in the sediment separation bottle provided in the present embodiment, the constriction portion 104 is detachably fixed to the lower end of the bottle 101, and the liquid discharge port 107 is disposed in the constriction portion 104; as shown in fig. 6, the necking part 104 and the bottle body 101 are detachably connected, so that the necking part 104 and the bottle body 101 can be conveniently separated, the bottle body 101 can be conveniently and independently separated, and precipitates with large volume can be conveniently taken out from the upper end of the necking part 104 (the requirement that part of precipitates are inconvenient to discharge from the stock outlet 105) and are convenient to use.

For the detachable connection, there are various embodiments, for example, the lower end of the bottle body 101 is provided with an external thread, the upper end of the necking part 104 is provided with an internal thread matched with the external thread, as shown in fig. 6, the detachable connection is realized by the matching of the external thread and the internal thread, and the necking part 104 and the bottle body 101 jointly enclose the internal cavity 113.

Example 3

The main difference between this embodiment 3 and the above embodiment 2 is that in the sedimentation separation bottle provided in this embodiment, the bottom cover 201 is further provided with a communication port, as shown in fig. 7, the communication port is provided with a communication pipe 202, and the communication pipe 202 is provided with a valve 108 so as to control the on/off of the communication port. In the practical use process, when the sediment at the bottom of the sediment separation bottle needs to be taken out, a user can open the valve 108 first, and liquid around the sediment is drained through the communication port, so that only the sediment remains at the bottom of the sediment separation bottle, then the user closes the valve 108 and opens the bottom cover 201, and thus the sediment with low water content (namely, the sediment which is relatively dry) can be obtained, and the subsequent detection and diagnosis are facilitated.

In order to facilitate the pouring of the sediment and the suspension collected at the bottom of the sediment separation bottle into the test tube, as shown in fig. 7, the lower end surface of the connection pipe 202 has an inclined structure so as to perform a drainage function during the transfer of the sediment and/or the suspension, which is more convenient for operation.

It is understood that the communication pipe 202 may be a hard pipe or a flexible pipe.

Example 4

In the prior art, the supernatant separated from the collected thoracoabdominal water is usually directly poured off, and because the supernatant inevitably contains the components of cells and the like of a patient, the biological safety problem exists, and no solution is provided in the prior art; to solve this problem, the present embodiment is mainly different from the above-mentioned embodiments 1, 2 or 3 in that, in the sedimentation separation bottle provided in the present embodiment, a recycling portion 301 for storing the supernatant is further provided outside the necking portion 104, the recycling portion 301 has a closed storage cavity 302, and the volume of the storage cavity 302 is greater than or equal to the volume of the internal cavity 113, so as to store the supernatant,

in order to control the communication between the recovery part 301 and the bottle 101, as shown in fig. 8-10, in one embodiment, an annular protrusion is disposed on a side surface of the bottle 101, first latches 407 are disposed on two sides of the annular protrusion, respectively, the annular protrusion is further provided with a first communication hole 403, the first communication hole 403 is located between the two first latches 407, an annular groove is disposed on an outer side of the pair of annular protrusions, an annular sealing ring 404 is fixed in the annular groove, the annular sealing ring 404 is provided with a communication port 405, and the communication port 405 is communicated with the first communication hole 403;

the recycling part 301 is of an annular structure, two second latches 304 respectively matched with the first latches 407 are arranged on the inner side of the recycling part 301, the adjusting part is a second communicating hole 303 arranged between the two second latches 304, the second communicating hole 303 is communicated with the storage cavity 302, the recycling part 301 is movably connected to the annular protrusion through the matching of the second latches 304 and the first latches 407, and the annular sealing ring 404 is radially compressed, so that not only can the effect of pressure sealing be achieved, but also the relative position of the second communicating hole 303 and the communicating port 405 can be adjusted through rotating the recycling part 301, and when the second communicating hole 303 rotates to a position corresponding to the communicating port 405, the second communicating hole 303 is communicated with the recycling part 301, so that the bottle 101 can be communicated with the recycling part 301;

as shown in fig. 8, 9 or 10, the first latch 407 is an annular block disposed on the upper and lower sides of the annular protrusion, and the second latch 304 is an annular latch having an L-shaped cross section, and the annular latch can cooperate with the annular block, so as to fix the recovery portion 301, and enable the recovery portion 301 to rotate relative to the bottle 101 under the action of external force, thereby achieving the movable connection.

In order to facilitate the separation of the necked portion 104 from the bottle body 101, in a further embodiment, the bottle body 101 further comprises an annular connector 401, the lower end of the bottle body 101 is provided with an external thread 114 or an internal thread 402, the annular connector 401 is provided with an internal thread 402 or an external thread 114 matched with the external thread 114 or the internal thread 402 so as to realize a threaded connection, and the annular protrusion is disposed on the annular connector 401, as shown in fig. 9 or 10.

In order to avoid the problem that the recovering part 301 may rotate relative to the necking part 104 during the process of connecting the necking part 104 and the bottle body 101, so that the necking part 104 and the bottle body 101 cannot be tightened, in a further aspect, the outer side surface of the annular connecting head 401 is further provided with a first stopper 406, the recovering part 301 is provided with a second stopper 305 matched with the first stopper 406, the recovering part 301 is limited to rotate only one turn relative to the annular connecting head 401 by the matching of the first stopper 406 and the second stopper 305, for example, the first stopper 406 and the second stopper 305 may be respectively arranged in the same plane perpendicular to the central line of the bottle body 101, so that the first stopper 406 and the second stopper 305 may interfere with each other, thereby achieving the purpose of limiting, i.e., the second stopper 305 may rotate one turn relative to the necking part 104 only under the driving of the recovering part 301, in this process, the second communication hole 303 and the communication port 405 may coincide once so as to achieve communication.

The application method of the precipitation separation bottle provided by the embodiment is as follows:

1. the recovery part 301 is rotated such that the second stopper 305 is located between the first stopper 406 and the communication port 405 in the circumferential direction, and the second stopper 305 is rotated in a direction away from the communication port 405 during the tightening of the recovery part 301 with the bottle 101, at which time the internal cavity 113 is not communicated with the storage cavity 302 but is communicated with the necked part 104.

2. Adding the collected pleural effusion fluid to the internal cavity 113 of the vial 101, and allowing it to settle so that the cell suspension and/or sediment to be collected can settle into the constriction 104;

3. after the sedimentation is finished, the recovery part 301 is rotated reversely relative to the bottle body 101 (i.e. in the opposite direction to the rotation direction in the initial screwing process), and when the second communication hole 303 is inevitably rotated to the position corresponding to the communication port 405 within one turn, the two are communicated, so that the bottle body 101 can be communicated with the recovery part 301, and the supernatant in the bottle body 101 can automatically enter the storage cavity 302 of the recovery part 301 under the action of gravity;

4. after the supernatant of the bottle body 101 completely enters the recovery part 301, the recovery part 301 is continuously rotated, so that the second communication hole 303 and the communication port 405 are dislocated, the purpose of sealing the storage cavity 302 is achieved, the liquid in the storage cavity is prevented from flowing out, the supernatant is prevented from being randomly discharged, and the biological safety problem is effectively solved;

5. the recycling part 301 continues to rotate until the second stopper 305 contacts the first stopper 406, and then the recycling part 301 continues to rotate, at this time, the recycling part 301 can drive the annular connector 401 relative to the bottle body 101, so that the necking part 104, the annular connector 401 and the recycling part 301 can be separated from the bottle body 101 as a whole, the precipitate can be taken away from the upper part of the necking part 104 conveniently, or the precipitate can be discharged from a sample discharge port at the lower part of the necking part 104, and the used necking part 104, the annular connector 401, the recycling part 301 and the supernatant sealed in the recycling part 301 can be used as a whole for subsequent waste treatment, and the recycling part is very environment-friendly and can effectively avoid the biological safety problem caused by random discharge.

It is understood that the recycling portion 301 has various shapes and configurations, such as a ring shape, etc., and as shown in fig. 8, the base 109 can also be directly disposed at the lower end of the recycling portion 301, which is not described in detail herein.

The above description is only for the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art can easily think of the changes or substitutions within the technical scope of the present invention, and all should be covered within the protection scope of the present invention.

Claims (10)

1. The utility model provides a pleuroperitoneal fluid sedimentation and separation bottle, its characterized in that, is including the storage part that is used for holding pleuroperitoneal fluid, the storage part is provided with the inside cavity that is used for holding pleuroperitoneal fluid, and the upper portion of storage part is provided with the inlet that is used for packing into pleuroperitoneal fluid and is used for dismantling the closure the sealing member of inlet, and the bottom of storage part is provided with the stock layout mouth that is used for discharging the target cell and is used for controlling stock layout mouth opens/confined control piece, and the side of storage part lower part is provided with the leakage fluid dram that is used for discharging the supernatant and is used for controlling the regulating part that the leakage fluid dram switches on/breaks off, inlet.

2. The pleural ascites sedimentation and separation bottle according to claim 1, wherein the storage part comprises a bottle body, the liquid inlet is disposed at an upper portion of the bottle body, a necking part having a gradually decreasing inner diameter is disposed at a lower end of the bottle body, the sample discharge port is disposed at a lower end of the necking part, a base for supporting the bottle body is disposed at an outer side of the necking part, and the liquid discharge port is disposed at the bottle body or the necking part.

3. The pleural ascites sedimentation and separation bottle of claim 2, wherein the base has a cylindrical structure;

or the base comprises at least three supporting sheets, the supporting sheets are respectively distributed along the circumferential direction of the bottle body, the upper ends of the supporting sheets are respectively connected with the bottle body or the necking part, and the supporting sheets are used for supporting the bottle body.

4. The pleural ascites sedimentation and separation bottle according to claim 2, wherein the constriction is detachably fixed to a lower end of the body, and the drain port is provided in the constriction.

5. The pleural effusion precipitation separation bottle of claim 2, wherein the sealing element is a rubber plug, or the sealing element is a sealing cover provided with a threaded hole provided with an internal thread, and the liquid inlet is provided with an external thread adapted to the internal thread.

6. The pleural ascites sedimentation and separation bottle of claim 2, wherein the control member includes a bottom cap detachably fixed to the drain port;

the lower end of the necking part is provided with an external thread, and the bottom cover is provided with an internal thread matched with the external thread; or the lower end of the necking part is provided with a clamping groove, the bottom cover is provided with a buckle matched with the clamping groove, and the stock layout port is sealed through the matching of the buckle and the clamping groove.

7. The pleural effusion precipitation separation bottle of any one of claims 2-6, characterized in that a recovery part for storing supernatant is further arranged outside the constriction part, the recovery part has a closed storage cavity, and the volume of the storage cavity is greater than or equal to the volume of the internal cavity for storing supernatant;

an annular bulge is arranged on the side face of the bottle body, first lock catches are respectively arranged on two sides of the annular bulge, a first connecting hole is further formed in the annular bulge, the first connecting hole is located between the two first lock catches, an annular groove is formed in the outer side of the pair of the annular bulges, an annular sealing ring is fixed in the annular groove, a communicating opening is formed in the annular sealing ring, and the communicating opening is communicated with the first connecting hole;

the recycling portion is of an annular structure, two second lock catches respectively matched with the first lock catches are arranged on the inner side of the recycling portion, the adjusting portion is a second communicating hole formed between the two second lock catches, the second communicating hole is communicated with the storage cavity, the recycling portion is movably connected to the annular protrusion through the matching of the second lock catches and the first lock catches, and the annular sealing ring is enabled to be in a compression state along the radial direction.

8. The pleural effusion precipitation separation bottle of claim 7, wherein the first lock catch is an annular fixture block disposed on the upper and lower sides of the annular protrusion, and the second lock catch is an annular catch with an L-shaped cross section, and the annular catch is matched with the annular fixture block.

9. The pleural effusion and ascites precipitation separation bottle according to claim 7, further comprising an annular connector, wherein the lower end of the bottle body is provided with an external thread or an internal thread, the annular connector is provided with an internal thread or an external thread matched with the external thread or the internal thread, and the annular protrusion is arranged on the annular connector.

10. The pleural effusion precipitation separation bottle of claim 9, wherein the outer side of the annular connector is further provided with a first stop, the recovery part is provided with a second stop adapted to the first stop, and the recovery part is restricted to rotate only one turn relative to the annular connector by the cooperation of the first stop and the second stop.

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