TWI821765B - 含羅匹尼羅之貼附劑及羅匹尼羅之皮膚透過性之提升方法 - Google Patents

含羅匹尼羅之貼附劑及羅匹尼羅之皮膚透過性之提升方法 Download PDF

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Publication number
TWI821765B
TWI821765B TW110140142A TW110140142A TWI821765B TW I821765 B TWI821765 B TW I821765B TW 110140142 A TW110140142 A TW 110140142A TW 110140142 A TW110140142 A TW 110140142A TW I821765 B TWI821765 B TW I821765B
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TW
Taiwan
Prior art keywords
ropinirole
adhesive layer
mentioned
adhesive
group
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TW110140142A
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English (en)
Chinese (zh)
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TW202227052A (zh
Inventor
內田尚志
天野智史
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日商久光製藥股份有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW110140142A 2020-10-29 2021-10-28 含羅匹尼羅之貼附劑及羅匹尼羅之皮膚透過性之提升方法 TWI821765B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020-181280 2020-10-29
JP2020181280 2020-10-29

Publications (2)

Publication Number Publication Date
TW202227052A TW202227052A (zh) 2022-07-16
TWI821765B true TWI821765B (zh) 2023-11-11

Family

ID=81382322

Family Applications (1)

Application Number Title Priority Date Filing Date
TW110140142A TWI821765B (zh) 2020-10-29 2021-10-28 含羅匹尼羅之貼附劑及羅匹尼羅之皮膚透過性之提升方法

Country Status (8)

Country Link
US (1) US12440452B2 (enExample)
EP (1) EP4238563B1 (enExample)
JP (1) JP7284877B2 (enExample)
KR (1) KR102577838B1 (enExample)
CN (1) CN116322658B (enExample)
ES (1) ES3049508T3 (enExample)
TW (1) TWI821765B (enExample)
WO (1) WO2022091925A1 (enExample)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016535781A (ja) * 2013-11-03 2016-11-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 経皮薬物送達のためのイオン性液体
CN107375249A (zh) * 2017-07-26 2017-11-24 徐静 一种含罗匹尼罗的缓释透皮贴剂及其应用
TW201834641A (zh) * 2017-02-24 2018-10-01 日商久光製藥股份有限公司 貼附劑及其包裝體
TW201841638A (zh) * 2017-04-19 2018-12-01 日商帝國製藥股份有限公司 含有盧帕他定（ｒｕｐａｔａｄｉｎｅ）之貼附劑
TW201900156A (zh) * 2013-10-07 2019-01-01 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物

Family Cites Families (14)

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US5872111A (en) * 1997-05-19 1999-02-16 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising glycosylamide surfactants
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
JP5485135B2 (ja) 2008-02-27 2014-05-07 久光製薬株式会社 貼付製剤
JP5546013B2 (ja) * 2008-02-27 2014-07-09 久光製薬株式会社 貼付剤及び包装体
WO2010134433A1 (ja) 2009-05-21 2010-11-25 久光製薬株式会社 経皮吸収製剤
JP5631854B2 (ja) * 2010-12-13 2014-11-26 久光製薬株式会社 医薬組成物および貼付剤
ES2657016T3 (es) 2011-05-31 2018-03-01 Hisamitsu Pharmaceutical Co., Inc. Parche cutáneo adhesivo que contiene ropinirol y producto envasado del mismo
US9155710B2 (en) 2011-05-31 2015-10-13 Hisamitsu Pharmaceutical Co., Inc. Ropinirole-containing patch and package thereof
US9849095B2 (en) * 2011-12-01 2017-12-26 Teikoku Seiyaku Co., Ltd. Ropinirole-containing adhesive patch
EP2887962B1 (en) * 2012-08-24 2021-05-26 Integurx Therapeutics LLC Chemical compositions and methods for enhancing transdermal delivery of therapeutic agents
JP6373061B2 (ja) * 2014-05-23 2018-08-15 帝國製薬株式会社 経皮投与製剤
WO2017037812A1 (ja) * 2015-08-29 2017-03-09 株式会社メドレックス 酸捕捉剤を含有する貼付製剤
US10392371B2 (en) * 2015-10-01 2019-08-27 Senomyx, Inc. Compounds useful as modulators of TRPM8
US20200297654A1 (en) * 2017-10-17 2020-09-24 Lubrizol Advanced Materials, Inc. Composition and device for delivery of active agents to skin surfaces

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201900156A (zh) * 2013-10-07 2019-01-01 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
JP2016535781A (ja) * 2013-11-03 2016-11-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 経皮薬物送達のためのイオン性液体
TW201834641A (zh) * 2017-02-24 2018-10-01 日商久光製藥股份有限公司 貼附劑及其包裝體
TW201841638A (zh) * 2017-04-19 2018-12-01 日商帝國製藥股份有限公司 含有盧帕他定（ｒｕｐａｔａｄｉｎｅ）之貼附劑
CN107375249A (zh) * 2017-07-26 2017-11-24 徐静 一种含罗匹尼罗的缓释透皮贴剂及其应用

Also Published As

Publication number Publication date
KR102577838B1 (ko) 2023-09-12
WO2022091925A1 (ja) 2022-05-05
JP7284877B2 (ja) 2023-05-31
CN116322658B (zh) 2025-09-26
TW202227052A (zh) 2022-07-16
KR20230088789A (ko) 2023-06-20
EP4238563A1 (en) 2023-09-06
EP4238563B1 (en) 2025-09-24
EP4238563A4 (en) 2024-10-02
US20240016758A1 (en) 2024-01-18
US12440452B2 (en) 2025-10-14
ES3049508T3 (en) 2025-12-17
JPWO2022091925A1 (enExample) 2022-05-05
CN116322658A (zh) 2023-06-23

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