CN116322658B - 含罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性的提升方法 - Google Patents

含罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性的提升方法

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Publication number
CN116322658B
CN116322658B CN202180067163.XA CN202180067163A CN116322658B CN 116322658 B CN116322658 B CN 116322658B CN 202180067163 A CN202180067163 A CN 202180067163A CN 116322658 B CN116322658 B CN 116322658B
Authority
CN
China
Prior art keywords
ropinirole
adhesive
adhesive layer
sodium
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202180067163.XA
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English (en)
Chinese (zh)
Other versions
CN116322658A (zh
Inventor
内田尚志
天野智史
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of CN116322658A publication Critical patent/CN116322658A/zh
Application granted granted Critical
Publication of CN116322658B publication Critical patent/CN116322658B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202180067163.XA 2020-10-29 2021-10-21 含罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性的提升方法 Active CN116322658B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-181280 2020-10-29
JP2020181280 2020-10-29
PCT/JP2021/038892 WO2022091925A1 (ja) 2020-10-29 2021-10-21 ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法

Publications (2)

Publication Number Publication Date
CN116322658A CN116322658A (zh) 2023-06-23
CN116322658B true CN116322658B (zh) 2025-09-26

Family

ID=81382322

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180067163.XA Active CN116322658B (zh) 2020-10-29 2021-10-21 含罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性的提升方法

Country Status (7)

Country Link
US (1) US12440452B2 (enExample)
EP (1) EP4238563B1 (enExample)
JP (1) JP7284877B2 (enExample)
KR (1) KR102577838B1 (enExample)
CN (1) CN116322658B (enExample)
TW (1) TWI821765B (enExample)
WO (1) WO2022091925A1 (enExample)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110300582A (zh) * 2017-02-24 2019-10-01 久光制药株式会社 贴附剂及其包装体

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US5872111A (en) * 1997-05-19 1999-02-16 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising glycosylamide surfactants
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
JP5546013B2 (ja) * 2008-02-27 2014-07-09 久光製薬株式会社 貼付剤及び包装体
US20110028880A1 (en) 2008-02-27 2011-02-03 Hisamitsu Pharmaceutical Co., Inc. Patch
ES2513691T3 (es) 2009-05-21 2014-10-27 Hisamitsu Pharmaceutical Co., Inc. Preparación transdérmica
JP5631854B2 (ja) 2010-12-13 2014-11-26 久光製薬株式会社 医薬組成物および貼付剤
JPWO2012165254A1 (ja) 2011-05-31 2015-02-23 久光製薬株式会社 ロピニロール含有貼付剤及びその包装体
ES2641651T3 (es) * 2011-05-31 2017-11-10 Hisamitsu Pharmaceutical Co., Inc. Parche que contiene ropinirol y envase para el mismo
JP6104173B2 (ja) 2011-12-01 2017-03-29 帝國製薬株式会社 ロピニロール含有貼付剤
CN104736176B (zh) * 2012-08-24 2017-10-13 英特格拉斯疗法有限公司 用于增强治疗剂透皮递送的化学组合物和方法
TWI709417B (zh) * 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
WO2015066647A2 (en) 2013-11-03 2015-05-07 The Regents Of The University Of California Ionic liquids for transdermal drug delivery
JP6373061B2 (ja) 2014-05-23 2018-08-15 帝國製薬株式会社 経皮投与製剤
WO2017037812A1 (ja) 2015-08-29 2017-03-09 株式会社メドレックス 酸捕捉剤を含有する貼付製剤
JP6865743B2 (ja) * 2015-10-01 2021-04-28 フィルメニッヒ インコーポレイテッドＦｉｒｍｅｎｉｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｔｒｐｍ８の活性調節因子として有用な化合物
TWI825013B (zh) * 2017-04-19 2023-12-11 日商帝國製藥股份有限公司 含有盧帕他定（ｒｕｐａｔａｄｉｎｅ）之貼附劑
CN107375249A (zh) * 2017-07-26 2017-11-24 徐静 一种含罗匹尼罗的缓释透皮贴剂及其应用
EP3700511A1 (en) * 2017-10-17 2020-09-02 Lubrizol Advanced Materials, Inc. Composition and device for delivery of active agents to skin surfaces

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110300582A (zh) * 2017-02-24 2019-10-01 久光制药株式会社 贴附剂及其包装体

Also Published As

Publication number Publication date
KR102577838B1 (ko) 2023-09-12
CN116322658A (zh) 2023-06-23
TW202227052A (zh) 2022-07-16
TWI821765B (zh) 2023-11-11
JPWO2022091925A1 (enExample) 2022-05-05
EP4238563A4 (en) 2024-10-02
WO2022091925A1 (ja) 2022-05-05
JP7284877B2 (ja) 2023-05-31
EP4238563A1 (en) 2023-09-06
EP4238563B1 (en) 2025-09-24
KR20230088789A (ko) 2023-06-20
US20240016758A1 (en) 2024-01-18
US12440452B2 (en) 2025-10-14

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