TWI801942B - 適用於口服的glp-1及gip受體共促效劑 - Google Patents
適用於口服的glp-1及gip受體共促效劑 Download PDFInfo
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- TWI801942B TWI801942B TW110126883A TW110126883A TWI801942B TW I801942 B TWI801942 B TW I801942B TW 110126883 A TW110126883 A TW 110126883A TW 110126883 A TW110126883 A TW 110126883A TW I801942 B TWI801942 B TW I801942B
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Classifications
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- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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- C07K—PEPTIDES
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Landscapes
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| US202063055026P | 2020-07-22 | 2020-07-22 | |
| US63/055,026 | 2020-07-22 | ||
| EP20192414.9 | 2020-08-24 | ||
| EP20192414 | 2020-08-24 | ||
| US202163156988P | 2021-03-05 | 2021-03-05 | |
| US63/156,988 | 2021-03-05 |
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| TW202208411A TW202208411A (zh) | 2022-03-01 |
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| TW110126883A TWI801942B (zh) | 2020-07-22 | 2021-07-22 | 適用於口服的glp-1及gip受體共促效劑 |
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| TW111150185A TW202315883A (zh) | 2020-07-22 | 2021-07-22 | 適用於口服的glp-1及gip受體共促效劑 |
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| IL (1) | IL299701A (enExample) |
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| KR102446310B1 (ko) | 2020-07-22 | 2022-09-23 | 노보 노르디스크 에이/에스 | 경구 전달에 적합한 glp-1 및 gip 수용체에서의 공-작용제 |
| WO2023012263A1 (en) | 2021-08-04 | 2023-02-09 | Novo Nordisk A/S | Solid oral peptide formulations |
| TW202330584A (zh) | 2022-01-20 | 2023-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 前藥及其用途 |
| CN119080887A (zh) * | 2022-07-13 | 2024-12-06 | 杭州中美华东制药有限公司 | Glp-1/gip双激动剂及其制备方法和用途 |
| WO2024110614A1 (en) | 2022-11-25 | 2024-05-30 | Novo Nordisk A/S | Oral administration of peptide therapeutics, such as glp-1 |
| CN117646017A (zh) * | 2023-11-02 | 2024-03-05 | 中国人民解放军海军军医大学 | Gip/glp-1双激动剂多肽编码基因、及其重组乳酸菌和应用 |
| WO2025108381A1 (zh) * | 2023-11-22 | 2025-05-30 | 杭州中美华东制药有限公司 | Glp-1r/gipr双靶点激动剂在制备动物药中的用途 |
| JP7755031B2 (ja) | 2023-11-30 | 2025-10-15 | ノヴォ ノルディスク アー／エス | Ｇｌｐ－１、ｇｉｐ、およびアミリン受容体の三重作動薬 |
| WO2025133045A1 (en) | 2023-12-22 | 2025-06-26 | Novo Nordisk A/S | Fermentation process |
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2021
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- 2021-07-22 IL IL299701A patent/IL299701A/en unknown
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- 2021-07-22 TW TW111150185A patent/TW202315883A/zh unknown
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- 2021-07-22 US US17/383,192 patent/US20220177538A1/en not_active Abandoned
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| AU2021312323A1 (en) | 2023-02-02 |
| PE20231841A1 (es) | 2023-11-21 |
| TW202315883A (zh) | 2023-04-16 |
| BR112023000270A2 (pt) | 2023-01-31 |
| US20220125940A1 (en) | 2022-04-28 |
| IL299701A (en) | 2023-03-01 |
| TW202208411A (zh) | 2022-03-01 |
| JP7581385B2 (ja) | 2024-11-12 |
| US20230120597A1 (en) | 2023-04-20 |
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