TWI780097B - 於活體外進行抗體之糖基化工程 - Google Patents
於活體外進行抗體之糖基化工程 Download PDFInfo
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- TWI780097B TWI780097B TW106144931A TW106144931A TWI780097B TW I780097 B TWI780097 B TW I780097B TW 106144931 A TW106144931 A TW 106144931A TW 106144931 A TW106144931 A TW 106144931A TW I780097 B TWI780097 B TW I780097B
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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2017
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- 2017-12-19 EP EP17829955.8A patent/EP3559248B2/en active Active
- 2017-12-19 MX MX2019006266A patent/MX2019006266A/es unknown
- 2017-12-19 KR KR1020197017701A patent/KR102317884B1/ko active Active
- 2017-12-19 WO PCT/EP2017/083429 patent/WO2018114877A1/en not_active Ceased
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- 2017-12-19 CN CN202411870260.4A patent/CN119685431A/zh active Pending
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| JP2020501577A (ja) | 2020-01-23 |
| AU2017384276B9 (en) | 2020-11-26 |
| AU2017384276B2 (en) | 2020-07-02 |
| KR20190082942A (ko) | 2019-07-10 |
| US20240101643A1 (en) | 2024-03-28 |
| EP3559248A1 (en) | 2019-10-30 |
| CN110088291A (zh) | 2019-08-02 |
| WO2018114877A1 (en) | 2018-06-28 |
| TW201835333A (zh) | 2018-10-01 |
| EP3559248B1 (en) | 2021-11-17 |
| IL267351A (en) | 2019-08-29 |
| EP3559248B2 (en) | 2024-11-20 |
| JP6850351B2 (ja) | 2021-03-31 |
| AU2017384276A1 (en) | 2019-05-30 |
| KR102317884B1 (ko) | 2021-10-26 |
| CA3044920C (en) | 2022-06-28 |
| US20200165320A1 (en) | 2020-05-28 |
| MX2019006266A (es) | 2019-08-21 |
| BR112019010485A2 (pt) | 2019-09-10 |
| CN119685431A (zh) | 2025-03-25 |
| CA3044920A1 (en) | 2018-06-28 |
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