TWI677348B - 一種改善心臟病變的方法 - Google Patents

一種改善心臟病變的方法 Download PDF

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Publication number
TWI677348B
TWI677348B TW106120460A TW106120460A TWI677348B TW I677348 B TWI677348 B TW I677348B TW 106120460 A TW106120460 A TW 106120460A TW 106120460 A TW106120460 A TW 106120460A TW I677348 B TWI677348 B TW I677348B
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TW
Taiwan
Prior art keywords
plasminogen
pro
gly
glu
thr
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TW106120460A
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English (en)
Chinese (zh)
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TW201822798A (zh
Inventor
李季男
Jinan Li
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大陸商深圳瑞健生命科學研究院有限公司
Talengen Institute Of Life Sciences, Co. Ltd.
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Publication of TW201822798A publication Critical patent/TW201822798A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW106120460A 2016-12-15 2017-06-19 一種改善心臟病變的方法 TWI677348B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN2016110174 2016-12-15
??PCT/CN2016/110172 2016-12-15
WOPCT/CN2016/110168 2016-12-15
CN2016110172 2016-12-15
??PCT/CN2016/110174 2016-12-15
WOPCT/CN2016/110172 2016-12-15
CN2016110168 2016-12-15
WOPCT/CN2016/110174 2016-12-15
??PCT/CN2016/110168 2016-12-15

Publications (2)

Publication Number Publication Date
TW201822798A TW201822798A (zh) 2018-07-01
TWI677348B true TWI677348B (zh) 2019-11-21

Family

ID=62558191

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106120460A TWI677348B (zh) 2016-12-15 2017-06-19 一種改善心臟病變的方法

Country Status (7)

Country Link
US (1) US11389515B2 (https=)
EP (1) EP3556385A4 (https=)
JP (1) JP7194440B2 (https=)
CN (1) CN110114081A (https=)
CA (1) CA3047175A1 (https=)
TW (1) TWI677348B (https=)
WO (1) WO2018107707A1 (https=)

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WO2018107686A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种治疗动脉粥样硬化及其并发症的方法
JP7213552B2 (ja) 2016-12-15 2023-01-27 タレンゲン インターナショナル リミテッド 肝の繊維化を予防及び治療するための方法
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
TWI677348B (zh) 2016-12-15 2019-11-21 大陸商深圳瑞健生命科學研究院有限公司 一種改善心臟病變的方法
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EP4140498A4 (en) 2020-05-11 2023-11-01 Talengen International Limited Method and drug for treating spinal muscular atrophy

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Also Published As

Publication number Publication date
CN110114081A (zh) 2019-08-09
EP3556385A4 (en) 2020-12-30
TW201822798A (zh) 2018-07-01
WO2018107707A1 (zh) 2018-06-21
JP7194440B2 (ja) 2022-12-22
US11389515B2 (en) 2022-07-19
CA3047175A1 (en) 2018-06-21
JP2020502155A (ja) 2020-01-23
EP3556385A1 (en) 2019-10-23
US20190343931A1 (en) 2019-11-14

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