TWI662268B - 光學測量器 - Google Patents
光學測量器 Download PDFInfo
- Publication number
- TWI662268B TWI662268B TW105125313A TW105125313A TWI662268B TW I662268 B TWI662268 B TW I662268B TW 105125313 A TW105125313 A TW 105125313A TW 105125313 A TW105125313 A TW 105125313A TW I662268 B TWI662268 B TW I662268B
- Authority
- TW
- Taiwan
- Prior art keywords
- light
- light guide
- measuring device
- guide path
- optical measuring
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 68
- 238000005259 measurement Methods 0.000 claims abstract description 60
- 238000001514 detection method Methods 0.000 claims abstract description 18
- 230000031700 light absorption Effects 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 11
- 230000015572 biosynthetic process Effects 0.000 claims description 9
- 229920001971 elastomer Polymers 0.000 claims description 6
- 239000000806 elastomer Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 229920002050 silicone resin Polymers 0.000 claims description 4
- 239000011358 absorbing material Substances 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 63
- 238000002835 absorbance Methods 0.000 description 12
- 239000013076 target substance Substances 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 4
- 238000003752 polymerase chain reaction Methods 0.000 description 3
- AFYNADDZULBEJA-UHFFFAOYSA-N bicinchoninic acid Chemical compound C1=CC=CC2=NC(C=3C=C(C4=CC=CC=C4N=3)C(=O)O)=CC(C(O)=O)=C21 AFYNADDZULBEJA-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000012123 point-of-care testing Methods 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- -1 polydimethylsiloxane Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000009010 Bradford assay Methods 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 239000002041 carbon nanotube Substances 0.000 description 1
- 229910021393 carbon nanotube Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920005668 polycarbonate resin Polymers 0.000 description 1
- 239000004431 polycarbonate resin Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0332—Cuvette constructions with temperature control
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0221—Portable; cableless; compact; hand-held
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/064—Stray light conditioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/08—Optical fibres; light guides
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015-187762 | 2015-09-25 | ||
| JP2015187762A JP6433398B2 (ja) | 2015-09-25 | 2015-09-25 | 光学測定器 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201721126A TW201721126A (zh) | 2017-06-16 |
| TWI662268B true TWI662268B (zh) | 2019-06-11 |
Family
ID=58386137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW105125313A TWI662268B (zh) | 2015-09-25 | 2016-08-09 | 光學測量器 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10809185B2 (enExample) |
| JP (1) | JP6433398B2 (enExample) |
| CN (1) | CN108139324B (enExample) |
| TW (1) | TWI662268B (enExample) |
| WO (1) | WO2017051638A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019009209A1 (ja) * | 2017-07-04 | 2019-01-10 | 国立大学法人九州大学 | 光測定装置、導光部材及び光測定方法 |
| JP6924439B2 (ja) * | 2017-07-04 | 2021-08-25 | 国立大学法人九州大学 | 光測定装置、導光部材及び光測定方法 |
| WO2020054561A1 (ja) * | 2018-09-11 | 2020-03-19 | ウシオ電機株式会社 | マイクロプレートリーダー |
| CN111307678A (zh) * | 2019-12-05 | 2020-06-19 | 怀光智能科技（武汉）有限公司 | 一种细胞悬浮液浓度测量及配液装置和工作方法 |
| KR102821335B1 (ko) * | 2019-12-16 | 2025-06-13 | 주식회사 코사이언스 | 유전체 분자 진단용 휴대용 램프 ｐｃｒ 장치 |
| TWI728885B (zh) * | 2020-07-30 | 2021-05-21 | 思創影像科技股份有限公司 | 導光模組與應用此導光模組之生物檢測設備 |
| JP7425428B2 (ja) * | 2022-07-05 | 2024-01-31 | 国立大学法人 熊本大学 | 光学測定器用サンプルホルダおよび光学測定器 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006300741A (ja) * | 2005-04-21 | 2006-11-02 | Rohm Co Ltd | 光学測定用マイクロ流路及びマイクロ流体チップ |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4609991A (en) * | 1983-07-19 | 1986-09-02 | The United States Of America As Represented By The Department Of Health And Human Services | Automated system for determining the molecular weight and/or concentration of macromolecules via sedimentation equilibrium |
| US6195158B1 (en) * | 1995-11-21 | 2001-02-27 | Cme Telemetrix Inc. | Apparatus and method for rapid spectrophotometric pre-test screen of specimen for a blood analyzer |
| JP3688068B2 (ja) * | 1996-08-29 | 2005-08-24 | シスメックス株式会社 | 液体試料測定装置 |
| US6992759B2 (en) * | 2002-10-21 | 2006-01-31 | Nippon Shokubai Co., Ltd. | Sample holder for spectrum measurement and spectrophotometer |
| CN2679854Y (zh) * | 2004-03-02 | 2005-02-16 | 肖剑鸣 | 微型通道光子倍增管 |
| US7375815B2 (en) * | 2004-10-12 | 2008-05-20 | Agilent Technologies, Inc. | Optical devices, systems and method for producing a collimated light path |
| CN1865927A (zh) * | 2006-05-18 | 2006-11-22 | 中国科学院安徽光学精密机械研究所 | 面污染源排放通量的被动差分吸收光谱测量方法与装置 |
| CN100381788C (zh) * | 2006-08-23 | 2008-04-16 | 北京航空航天大学 | 一种高精度低成本星光模拟器 |
| JPWO2011135780A1 (ja) * | 2010-04-27 | 2013-07-18 | 信越化学工業株式会社 | 発光装置及びその製造方法 |
| US8951472B2 (en) * | 2010-07-19 | 2015-02-10 | Andalyze, Inc. | Portable fluorimetric apparatus, method and system |
| CN102175690B (zh) * | 2011-01-24 | 2012-11-28 | 宁波大学 | 一种红外玻璃内部宏观缺陷检测装置 |
| WO2012151473A2 (en) * | 2011-05-04 | 2012-11-08 | Luminex Corporation | Apparatus and methods for integrated sample preparation, reaction and detection |
| CN102954938B (zh) * | 2011-08-29 | 2014-08-27 | 中国科学院电子学研究所 | 基于微流控通道全反射集成光波导的吸收光度检测传感器 |
| KR101380368B1 (ko) * | 2012-09-18 | 2014-04-10 | 포항공과대학교 산학협력단 | 흡광 검출을 위한 흐름셀을 갖는 미세유체칩 및 이를 포함하는 흡광 검출 장치 |
| JP5947709B2 (ja) | 2012-12-27 | 2016-07-06 | 株式会社堀場製作所 | 分光分析方法及び分光分析装置 |
| US9488579B2 (en) * | 2013-01-22 | 2016-11-08 | Tecan Trading Ag | Optical measuring apparatus and method for the analysis of samples contained in liquid drops |
| CN103487144B (zh) * | 2013-08-29 | 2016-01-13 | 中国科学院长春光学精密机械与物理研究所 | 消杂光能力稳定的双光栅分光系统封装结构 |
| JP6331191B2 (ja) * | 2013-09-20 | 2018-05-30 | 国立大学法人九州大学 | 光測定装置、光測定方法、フィルタ部材及びフィルタ部材を生産する方法 |
| CN103762148B (zh) * | 2014-01-15 | 2016-03-02 | 山西长城微光器材股份有限公司 | 一种用于光电倍增管的微通道板 |
-
2015
- 2015-09-25 JP JP2015187762A patent/JP6433398B2/ja active Active
-
2016
- 2016-08-09 TW TW105125313A patent/TWI662268B/zh active
- 2016-08-17 WO PCT/JP2016/073992 patent/WO2017051638A1/ja not_active Ceased
- 2016-08-17 CN CN201680055549.8A patent/CN108139324B/zh active Active
-
2018
- 2018-03-22 US US15/933,053 patent/US10809185B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006300741A (ja) * | 2005-04-21 | 2006-11-02 | Rohm Co Ltd | 光学測定用マイクロ流路及びマイクロ流体チップ |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201721126A (zh) | 2017-06-16 |
| JP2017062184A (ja) | 2017-03-30 |
| US20180217052A1 (en) | 2018-08-02 |
| CN108139324A (zh) | 2018-06-08 |
| WO2017051638A1 (ja) | 2017-03-30 |
| CN108139324B (zh) | 2021-02-02 |
| US10809185B2 (en) | 2020-10-20 |
| JP6433398B2 (ja) | 2018-12-05 |
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