TWI599791B - 用於眼內透鏡之紫外光吸收材料及其用途 - Google Patents
用於眼內透鏡之紫外光吸收材料及其用途 Download PDFInfo
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- TWI599791B TWI599791B TW106102977A TW106102977A TWI599791B TW I599791 B TWI599791 B TW I599791B TW 106102977 A TW106102977 A TW 106102977A TW 106102977 A TW106102977 A TW 106102977A TW I599791 B TWI599791 B TW I599791B
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- monomer
- polymer
- iol
- moiety
- absorbing
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- 239000000178 monomer Substances 0.000 claims description 75
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- 238000000034 method Methods 0.000 claims description 17
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 16
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- 230000005540 biological transmission Effects 0.000 claims description 15
- 238000002834 transmittance Methods 0.000 claims description 14
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- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 claims description 5
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- 238000004519 manufacturing process Methods 0.000 claims description 4
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- 230000000379 polymerizing effect Effects 0.000 claims description 4
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 3
- FIDRAVVQGKNYQK-UHFFFAOYSA-N 1,2,3,4-tetrahydrotriazine Chemical group C1NNNC=C1 FIDRAVVQGKNYQK-UHFFFAOYSA-N 0.000 claims description 2
- 239000001301 oxygen Substances 0.000 claims description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 description 59
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- OKKRPWIIYQTPQF-UHFFFAOYSA-N Trimethylolpropane trimethacrylate Chemical compound CC(=C)C(=O)OCC(CC)(COC(=O)C(C)=C)COC(=O)C(C)=C OKKRPWIIYQTPQF-UHFFFAOYSA-N 0.000 description 10
- 125000000217 alkyl group Chemical group 0.000 description 10
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- -1 (4,6-diphenyl-1,3,5-triazin-2-yl)-3-hydroxyphenoxy moiety Chemical group 0.000 description 8
- WYGWHHGCAGTUCH-UHFFFAOYSA-N 2-[(2-cyano-4-methylpentan-2-yl)diazenyl]-2,4-dimethylpentanenitrile Chemical compound CC(C)CC(C)(C#N)N=NC(C)(C#N)CC(C)C WYGWHHGCAGTUCH-UHFFFAOYSA-N 0.000 description 7
- 238000007792 addition Methods 0.000 description 7
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
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- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 4
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Classifications
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
- A61F2002/16905—Having means on lens to reduce overall dimension of lens for insertion into small incision
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
- A61F2002/16905—Having means on lens to reduce overall dimension of lens for insertion into small incision
- A61F2002/169051—Segmented zones
- A61F2002/169053—Segments fold
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/16965—Lens includes ultraviolet absorber
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
- C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
- C08F220/1812—C12-(meth)acrylate, e.g. lauryl (meth)acrylate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
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- Engineering & Computer Science (AREA)
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- Dermatology (AREA)
- Electromagnetism (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Materials For Medical Uses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Prostheses (AREA)
- Eyeglasses (AREA)
- Optical Filters (AREA)
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| AU2012308340B2 (en) * | 2011-09-16 | 2016-08-11 | Benz Research And Development Corp. | Ultraviolet light absorbing materials for intraocular lens and uses thereof |
| JP6632378B2 (ja) | 2012-12-20 | 2020-01-22 | スリーエム イノベイティブ プロパティズ カンパニー | 紫外線吸収基を有するオリゴマーを含むフルオロポリマー組成物 |
| CN106456830B (zh) | 2014-04-18 | 2020-11-03 | 宾视研发公司 | 用于隐形眼镜和人工晶状体的(甲基)丙烯酰胺聚合物 |
| US11110689B2 (en) | 2014-06-25 | 2021-09-07 | 3M Innovative Properties Company | Pressure sensitive adhesive composition including ultraviolet light-absorbing oligomer |
| CN106661365B (zh) | 2014-06-25 | 2019-03-01 | 3M创新有限公司 | 包含至少一种低聚物的含氟聚合物组合物 |
| KR101706826B1 (ko) * | 2014-11-25 | 2017-02-15 | 삼성에스디아이 주식회사 | 고굴절률 아크릴계 화합물, 이의 제조방법, 이를 포함하는 광학시트 및 이를 포함하는 광학표시장치 |
| NZ731226A (en) * | 2015-05-20 | 2020-02-28 | Rxsight Inc | Method for modifying power of light adjustable lens |
| CN107709385B (zh) | 2015-06-25 | 2020-06-12 | 3M创新有限公司 | 包含紫外光吸收基团的共聚物和包含该共聚物的组合物 |
| CN105884704A (zh) * | 2016-04-26 | 2016-08-24 | 郑绍军 | 一类长支碳链三嗪紫外吸收剂化合物及其制备方法 |
| US10196470B2 (en) | 2016-05-16 | 2019-02-05 | Benz Research And Development Corp. | Hydrophobic intraocular lens |
| US10894111B2 (en) | 2016-12-16 | 2021-01-19 | Benz Research And Development Corp. | High refractive index hydrophilic materials |
| RU2728693C1 (ru) * | 2017-06-05 | 2020-07-31 | Алькон Инк. | Материалы для интраокулярной линзы с высоким показателем преломления и высоким числом аббе |
| CN110152059B (zh) * | 2019-05-07 | 2020-07-07 | 浙江大学 | 一种含有抗生素的人工晶状体及其制作方法 |
| MX2022012244A (es) * | 2020-03-30 | 2022-10-27 | Ppg Ind Ohio Inc | Metodo para preparar composiciones de polimeros de baja turbidez para su uso en materiales opticos con indice de refraccion alto. |
| CN112945577A (zh) * | 2021-03-04 | 2021-06-11 | 拾音汽车科技（上海）有限公司 | 一种解决乘用车车身ab柱批量钣金异响的方法 |
| CN113545884B (zh) * | 2021-04-06 | 2024-12-24 | 富螺(上海)医疗器械有限公司 | 人工晶状体 |
| CN113545887B (zh) * | 2021-04-06 | 2025-02-14 | 富螺(上海)医疗器械有限公司 | 人工晶状体 |
| CN113545886B (zh) * | 2021-04-06 | 2024-09-24 | 富螺(上海)医疗器械有限公司 | 人工晶状体的制作方法 |
| CN116462794A (zh) * | 2023-05-24 | 2023-07-21 | 天津世纪康泰生物医学工程有限公司 | 一种聚合物及其制备方法和用途 |
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| US5133745A (en) * | 1988-05-26 | 1992-07-28 | Alcon Laboratories, Inc. | Ultraviolet absorbing hydrogels |
| US6011081A (en) | 1995-04-14 | 2000-01-04 | Benz Research And Development Corp. | Contact lens having improved dimensional stability |
| JPH0928785A (ja) * | 1995-07-18 | 1997-02-04 | Asahi Denka Kogyo Kk | 眼科用レンズ |
| US6326448B1 (en) * | 1997-08-20 | 2001-12-04 | Menicon Co., Ltd. | Soft intraocular lens material |
| ZA9810605B (en) | 1997-11-21 | 1999-05-25 | Cytec Techonoly Corp | Trisaryl-1,3,5-triazine ultraviolet light absorbers |
| US6267784B1 (en) | 1998-05-01 | 2001-07-31 | Benz Research And Development Corporation | Intraocular lens and haptics made of a copolymer |
| US6096799A (en) | 1998-05-07 | 2000-08-01 | Benz Research & Development Corporation | Contact lens of high water content and high water balance |
| JP2001220543A (ja) * | 2000-02-09 | 2001-08-14 | Matsushita Electric Works Ltd | 紫外線吸収コーティング材樹脂組成物とそれを用いた塗装品 |
| US6864341B2 (en) * | 2001-11-02 | 2005-03-08 | Bausch & Lomb Incorporated | High refractive index aromatic-based prepolymer precursors |
| US7083646B2 (en) * | 2002-06-28 | 2006-08-01 | Bausch & Lomb Incorporated | Surface modification of functional group-containing intraocular lenses |
| WO2005047349A1 (en) | 2003-11-05 | 2005-05-26 | Benz Research And Development Corporation | Materials for making hydrophobic intraocular lens |
| US7387642B2 (en) | 2005-04-13 | 2008-06-17 | Benz Research And Development Corporation | Polymers for intraocular lenses |
| TW200726797A (en) * | 2005-09-27 | 2007-07-16 | Nippon Catalytic Chem Ind | Resin composition for forming UV-absorbing layer and UV-absorbing-layer-containing multilayer body |
| DE102007059470B3 (de) | 2007-12-11 | 2009-05-20 | *Acri.Tec Gmbh | Ophthalmologische Zusammensetzung und deren Verwendung |
| JP4272692B2 (ja) * | 2008-03-24 | 2009-06-03 | 株式会社日本触媒 | 紫外線遮蔽層形成用樹脂組成物に用いる変性ポリマーの製造方法、紫外線遮蔽層形成用樹脂組成物および紫外線遮蔽性積層体 |
| TWI453199B (zh) * | 2008-11-04 | 2014-09-21 | Alcon Inc | 用於眼用鏡片材料之紫外光／可見光吸收劑 |
| US9012582B2 (en) | 2009-08-13 | 2015-04-21 | Nissan Chemical Industries, Ltd. | Transparent high-refractive-index resin composition |
| WO2011069931A1 (de) | 2009-12-09 | 2011-06-16 | Basf Se | Formulierung von lichtempfindlichen pestiziden und uv-absorber haltigen kammpolymeren |
| AU2012308340B2 (en) * | 2011-09-16 | 2016-08-11 | Benz Research And Development Corp. | Ultraviolet light absorbing materials for intraocular lens and uses thereof |
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| TW201320983A (zh) | 2013-06-01 |
| US20130096273A1 (en) | 2013-04-18 |
| IL231543A0 (en) | 2014-04-30 |
| ES2904585T3 (es) | 2022-04-05 |
| MX2014003147A (es) | 2014-08-22 |
| TW201719195A (zh) | 2017-06-01 |
| HK1199648A1 (en) | 2015-07-10 |
| CA2848980C (en) | 2020-01-14 |
| IL231543B (en) | 2018-01-31 |
| KR102090839B1 (ko) | 2020-03-18 |
| ES2638897T3 (es) | 2017-10-24 |
| EP3272775B1 (en) | 2021-11-03 |
| BR112014006186A2 (pt) | 2017-04-11 |
| US9561302B2 (en) | 2017-02-07 |
| CN103930455A (zh) | 2014-07-16 |
| JP6105589B2 (ja) | 2017-03-29 |
| US20170165052A1 (en) | 2017-06-15 |
| MX365605B (es) | 2019-06-07 |
| JP2015502764A (ja) | 2015-01-29 |
| BR112014006186B1 (pt) | 2020-11-24 |
| EP2756013A1 (en) | 2014-07-23 |
| IN2014CN02491A (enExample) | 2015-06-19 |
| AU2012308340A1 (en) | 2014-05-01 |
| AU2012308340B2 (en) | 2016-08-11 |
| EP3272775A1 (en) | 2018-01-24 |
| US10172705B2 (en) | 2019-01-08 |
| TWI583363B (zh) | 2017-05-21 |
| WO2013040449A1 (en) | 2013-03-21 |
| CN103930455B (zh) | 2016-08-24 |
| KR20140062118A (ko) | 2014-05-22 |
| CA2848980A1 (en) | 2013-03-21 |
| EP2756013B1 (en) | 2017-05-31 |
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