TWI598586B - 川崎氏症之診斷與治療 - Google Patents
川崎氏症之診斷與治療 Download PDFInfo
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- TWI598586B TWI598586B TW104124138A TW104124138A TWI598586B TW I598586 B TWI598586 B TW I598586B TW 104124138 A TW104124138 A TW 104124138A TW 104124138 A TW104124138 A TW 104124138A TW I598586 B TWI598586 B TW I598586B
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- A—HUMAN NECESSITIES
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
- G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
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- G01N2333/5418—IL-7
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/7056—Selectin superfamily, e.g. LAM-1, GlyCAM, ELAM-1, PADGEM
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/328—Vasculitis, i.e. inflammation of blood vessels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028633P | 2014-07-24 | 2014-07-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201617613A TW201617613A (zh) | 2016-05-16 |
| TWI598586B true TWI598586B (zh) | 2017-09-11 |
Family
ID=55163743
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW104124138A TWI598586B (zh) | 2014-07-24 | 2015-07-24 | 川崎氏症之診斷與治療 |
| TW105135195A TWI655433B (zh) | 2014-07-24 | 2015-07-24 | 川崎氏症之診斷與治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW105135195A TWI655433B (zh) | 2014-07-24 | 2015-07-24 | 川崎氏症之診斷與治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10983133B2 (enExample) |
| JP (1) | JP6779200B2 (enExample) |
| KR (1) | KR102453756B1 (enExample) |
| CN (1) | CN106796221B (enExample) |
| CA (1) | CA2955214C (enExample) |
| TW (2) | TWI598586B (enExample) |
| WO (1) | WO2016014761A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI683905B (zh) * | 2017-11-21 | 2020-02-01 | 長庚醫療財團法人高雄長庚紀念醫院 | 用於檢測川崎氏病的方法及套組以及用於治療川崎氏病的方法 |
| KR102056405B1 (ko) * | 2018-04-05 | 2019-12-16 | (주)메디젠휴먼케어 | Ebf2 유전자 다형성을 이용한 가와사키병 발병 예측 방법 |
| US12247256B2 (en) | 2018-08-04 | 2025-03-11 | Imperial College Innovations Limited | Method of identifying a subject having Kawasaki disease |
| CN113834939A (zh) * | 2021-09-18 | 2021-12-24 | 胜亚生物科技(厦门)有限公司 | 一种用于检测川崎病及疗效评估的试剂、试剂盒及应用 |
| WO2024037387A1 (en) * | 2022-08-19 | 2024-02-22 | Tianjin Yunjian Medical Technology Co., Ltd. | Blood biomarkers and methods for diagnosis of acute kawasaki disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075236A (en) | 1987-04-24 | 1991-12-24 | Teijin Limited | Method of detecting kawasaki disease using anti-tumor necrosis antibody |
| EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
| WO2010025393A2 (en) | 2008-08-28 | 2010-03-04 | The Regents Of The University Of California | Protein biomarkers and methods for diagnosing kawasaki disease |
| WO2012112315A2 (en) * | 2011-02-20 | 2012-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosis of kawasaki disease |
| JP6072768B2 (ja) | 2011-04-15 | 2017-02-01 | チルドレンズ メディカル センター コーポレーション | 川崎病の診断マーカーおよび治療標的 |
| TWI609882B (zh) * | 2012-05-22 | 2018-01-01 | 必治妥美雅史谷比公司 | 雙特異性抗體及其使用方法 |
| WO2014043397A1 (en) * | 2012-09-12 | 2014-03-20 | Indiana University Research & Technology Corporation | Material and methods for diagnosing and treating kawasaki disease and kls |
-
2015
- 2015-07-23 JP JP2017503621A patent/JP6779200B2/ja active Active
- 2015-07-23 CA CA2955214A patent/CA2955214C/en active Active
- 2015-07-23 KR KR1020177001775A patent/KR102453756B1/ko active Active
- 2015-07-23 WO PCT/US2015/041687 patent/WO2016014761A1/en not_active Ceased
- 2015-07-23 US US15/327,280 patent/US10983133B2/en active Active
- 2015-07-23 CN CN201580040004.5A patent/CN106796221B/zh active Active
- 2015-07-24 TW TW104124138A patent/TWI598586B/zh active
- 2015-07-24 TW TW105135195A patent/TWI655433B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| US10983133B2 (en) | 2021-04-20 |
| TW201617613A (zh) | 2016-05-16 |
| KR102453756B1 (ko) | 2022-10-12 |
| TWI655433B (zh) | 2019-04-01 |
| CA2955214C (en) | 2023-03-21 |
| JP2017524933A (ja) | 2017-08-31 |
| WO2016014761A1 (en) | 2016-01-28 |
| TW201706600A (zh) | 2017-02-16 |
| JP6779200B2 (ja) | 2020-11-04 |
| CN106796221B (zh) | 2019-12-17 |
| CA2955214A1 (en) | 2016-01-28 |
| US20170153250A1 (en) | 2017-06-01 |
| CN106796221A (zh) | 2017-05-31 |
| KR20170039139A (ko) | 2017-04-10 |
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