TWI550089B - Evaluation of anti-tumor agents and therapeutic effects in patients with mutated colorectal cancer of KRAS gene - Google Patents
Evaluation of anti-tumor agents and therapeutic effects in patients with mutated colorectal cancer of KRAS gene Download PDFInfo
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- TWI550089B TWI550089B TW101129724A TW101129724A TWI550089B TW I550089 B TWI550089 B TW I550089B TW 101129724 A TW101129724 A TW 101129724A TW 101129724 A TW101129724 A TW 101129724A TW I550089 B TWI550089 B TW I550089B
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- Prior art keywords
- colorectal cancer
- kras gene
- patients
- chemotherapy
- patient
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011177838 | 2011-08-16 |
Publications (2)
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| EP3328394A4 (en) | 2015-07-30 | 2019-03-13 | ModernaTX, Inc. | CONCATEMEE peptide epitope RNAs |
| UA123403C2 (uk) * | 2016-02-05 | 2021-03-31 | Тайхо Фармасьютікал Ко., Лтд. | Спосіб лікування хворих на рак з тяжкою нирковою недостатністю |
| AU2017397458B2 (en) * | 2017-02-01 | 2025-07-10 | Modernatx, Inc. | RNA cancer vaccines |
| WO2018170245A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Broad spectrum influenza virus vaccine |
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| PL2746404T3 (pl) | 2018-04-30 |
| CN103764847A (zh) | 2014-04-30 |
| KR20140057328A (ko) | 2014-05-12 |
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| AU2012295841A1 (en) | 2014-04-03 |
| LT2746404T (lt) | 2018-04-25 |
| US20140213602A1 (en) | 2014-07-31 |
| KR101693090B1 (ko) | 2017-01-04 |
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