TWI549963B - 適於ｎｃｌ法之多胜肽片段之有效率的製造方法 - Google Patents
適於ｎｃｌ法之多胜肽片段之有效率的製造方法 Download PDFInfo
- Publication number
- TWI549963B TWI549963B TW101135056A TW101135056A TWI549963B TW I549963 B TWI549963 B TW I549963B TW 101135056 A TW101135056 A TW 101135056A TW 101135056 A TW101135056 A TW 101135056A TW I549963 B TWI549963 B TW I549963B
- Authority
- TW
- Taiwan
- Prior art keywords
- peptide
- peptide fragment
- group
- fragment
- terminal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5437—IL-13
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011210007 | 2011-09-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201321400A TW201321400A (zh) | 2013-06-01 |
| TWI549963B true TWI549963B (zh) | 2016-09-21 |
Family
ID=47995404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW101135056A TWI549963B (zh) | 2011-09-26 | 2012-09-25 | 適於ｎｃｌ法之多胜肽片段之有效率的製造方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140377807A1 (enExample) |
| EP (1) | EP2762485B1 (enExample) |
| JP (1) | JP6186278B2 (enExample) |
| KR (1) | KR101942608B1 (enExample) |
| CN (1) | CN104080796A (enExample) |
| AU (1) | AU2012317742B2 (enExample) |
| BR (1) | BR112014007174B1 (enExample) |
| CA (1) | CA2849752C (enExample) |
| IN (1) | IN2014CN02854A (enExample) |
| RU (1) | RU2605411C2 (enExample) |
| SG (2) | SG10201602024YA (enExample) |
| TW (1) | TWI549963B (enExample) |
| WO (1) | WO2013047372A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3868401A1 (en) * | 2020-02-21 | 2021-08-25 | Assistance Publique Hôpitaux de Paris | Optimization of peptide-melanin binding |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| WO2010150730A1 (ja) * | 2009-06-26 | 2010-12-29 | 大塚化学株式会社 | ペプチドチオエステル体の製造方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2218620C (en) | 1995-05-04 | 2007-02-27 | Stephen B. H. Kent | Synthesis of proteins by native chemical ligation |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| TWI325430B (en) | 2003-07-28 | 2010-06-01 | Yasuhiro Kajihara | Aminated complex type sugar chain derivative and its production method |
| JPWO2005095331A1 (ja) | 2004-03-31 | 2008-02-21 | 塩野義製薬株式会社 | 糖鎖−ペプチド結合剤 |
| JP2007114454A (ja) | 2005-10-20 | 2007-05-10 | Yamaha Corp | マイクロレンズアレイとその製法 |
| CA2647867C (en) | 2006-03-29 | 2015-11-03 | Otsuka Chemical Co., Ltd. | Method for production of peptide thioester compound |
| MX2009005780A (es) * | 2006-11-30 | 2009-06-10 | Nektar Therapeutics Al Corp | Metodo para preparar un conjugado de polimeros. |
| JP2010150730A (ja) | 2008-12-25 | 2010-07-08 | Soichiro Hayashi | 中手指節関節運動制限具 |
| TW201031749A (en) * | 2009-02-10 | 2010-09-01 | Otsuka Chemical Co Ltd | IgG-Fc fragment and method for manufacturing the same |
-
2012
- 2012-09-21 WO PCT/JP2012/074239 patent/WO2013047372A1/ja not_active Ceased
- 2012-09-21 CA CA2849752A patent/CA2849752C/en active Active
- 2012-09-21 AU AU2012317742A patent/AU2012317742B2/en not_active Ceased
- 2012-09-21 CN CN201280057905.1A patent/CN104080796A/zh active Pending
- 2012-09-21 EP EP12837234.9A patent/EP2762485B1/en active Active
- 2012-09-21 IN IN2854CHN2014 patent/IN2014CN02854A/en unknown
- 2012-09-21 SG SG10201602024YA patent/SG10201602024YA/en unknown
- 2012-09-21 US US14/347,547 patent/US20140377807A1/en not_active Abandoned
- 2012-09-21 RU RU2014115769/04A patent/RU2605411C2/ru active
- 2012-09-21 JP JP2013536233A patent/JP6186278B2/ja active Active
- 2012-09-21 KR KR1020147010021A patent/KR101942608B1/ko not_active Expired - Fee Related
- 2012-09-21 SG SG11201400936QA patent/SG11201400936QA/en unknown
- 2012-09-21 BR BR112014007174-8A patent/BR112014007174B1/pt not_active IP Right Cessation
- 2012-09-25 TW TW101135056A patent/TWI549963B/zh not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| WO2010150730A1 (ja) * | 2009-06-26 | 2010-12-29 | 大塚化学株式会社 | ペプチドチオエステル体の製造方法 |
Non-Patent Citations (1)
| Title |
|---|
| Jonathan P. Richardson and Derek Macmillan, Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation, Org. Biomol. Chem., 2008, 6, 3977–3982, 2008/09/05. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2849752A1 (en) | 2013-04-04 |
| TW201321400A (zh) | 2013-06-01 |
| IN2014CN02854A (enExample) | 2015-07-03 |
| BR112014007174B1 (pt) | 2021-11-30 |
| CN104080796A (zh) | 2014-10-01 |
| BR112014007174A2 (pt) | 2017-04-04 |
| AU2012317742A1 (en) | 2014-04-17 |
| SG10201602024YA (en) | 2016-04-28 |
| JPWO2013047372A1 (ja) | 2015-03-26 |
| SG11201400936QA (en) | 2014-10-30 |
| EP2762485B1 (en) | 2018-08-01 |
| KR101942608B1 (ko) | 2019-01-25 |
| KR20140091678A (ko) | 2014-07-22 |
| RU2014115769A (ru) | 2015-10-27 |
| AU2012317742B2 (en) | 2016-10-13 |
| CA2849752C (en) | 2020-06-23 |
| EP2762485A4 (en) | 2015-06-24 |
| JP6186278B2 (ja) | 2017-08-23 |
| EP2762485A1 (en) | 2014-08-06 |
| RU2605411C2 (ru) | 2016-12-20 |
| WO2013047372A1 (ja) | 2013-04-04 |
| US20140377807A1 (en) | 2014-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |