JP6186278B2 - Ncl法に適した、ポリペプチド断片の効率的な製造方法 - Google Patents
Ncl法に適した、ポリペプチド断片の効率的な製造方法 Download PDFInfo
- Publication number
- JP6186278B2 JP6186278B2 JP2013536233A JP2013536233A JP6186278B2 JP 6186278 B2 JP6186278 B2 JP 6186278B2 JP 2013536233 A JP2013536233 A JP 2013536233A JP 2013536233 A JP2013536233 A JP 2013536233A JP 6186278 B2 JP6186278 B2 JP 6186278B2
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide fragment
- group
- terminal side
- polypeptide
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5437—IL-13
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011210007 | 2011-09-26 | ||
| JP2011210007 | 2011-09-26 | ||
| PCT/JP2012/074239 WO2013047372A1 (ja) | 2011-09-26 | 2012-09-21 | Ncl法に適した、ポリペプチド断片の効率的な製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2013047372A1 JPWO2013047372A1 (ja) | 2015-03-26 |
| JP6186278B2 true JP6186278B2 (ja) | 2017-08-23 |
Family
ID=47995404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536233A Active JP6186278B2 (ja) | 2011-09-26 | 2012-09-21 | Ncl法に適した、ポリペプチド断片の効率的な製造方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140377807A1 (enExample) |
| EP (1) | EP2762485B1 (enExample) |
| JP (1) | JP6186278B2 (enExample) |
| KR (1) | KR101942608B1 (enExample) |
| CN (1) | CN104080796A (enExample) |
| AU (1) | AU2012317742B2 (enExample) |
| BR (1) | BR112014007174B1 (enExample) |
| CA (1) | CA2849752C (enExample) |
| IN (1) | IN2014CN02854A (enExample) |
| RU (1) | RU2605411C2 (enExample) |
| SG (2) | SG11201400936QA (enExample) |
| TW (1) | TWI549963B (enExample) |
| WO (1) | WO2013047372A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3868401A1 (en) * | 2020-02-21 | 2021-08-25 | Assistance Publique Hôpitaux de Paris | Optimization of peptide-melanin binding |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69521815T2 (de) | 1995-05-04 | 2002-04-04 | The Scripps Research Institute, La Jolla | Proteinsynthese mittels nativer chemischer ligation (07.01.97) |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| JP4607017B2 (ja) | 2003-07-28 | 2011-01-05 | 大塚化学株式会社 | アミノ化複合型糖鎖誘導体及びその製造方法 |
| WO2005095331A1 (ja) | 2004-03-31 | 2005-10-13 | Shionogi & Co., Ltd. | 糖鎖-ペプチド結合剤 |
| JP2007114454A (ja) | 2005-10-20 | 2007-05-10 | Yamaha Corp | マイクロレンズアレイとその製法 |
| CN101437836B (zh) | 2006-03-29 | 2013-07-24 | 株式会社糖锁工学研究所 | 肽的硫酯化合物的制造方法 |
| WO2008066902A2 (en) * | 2006-11-30 | 2008-06-05 | Nektar Therapeutics Al, Corporation | Method for preparing a polymer conjugate |
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| JP2010150730A (ja) | 2008-12-25 | 2010-07-08 | Soichiro Hayashi | 中手指節関節運動制限具 |
| TW201031749A (en) * | 2009-02-10 | 2010-09-01 | Otsuka Chemical Co Ltd | IgG-Fc fragment and method for manufacturing the same |
| SG176300A1 (en) | 2009-06-26 | 2012-01-30 | Otsuka Chemical Co Ltd | Process for production of peptide thioester |
-
2012
- 2012-09-21 EP EP12837234.9A patent/EP2762485B1/en active Active
- 2012-09-21 RU RU2014115769/04A patent/RU2605411C2/ru active
- 2012-09-21 CN CN201280057905.1A patent/CN104080796A/zh active Pending
- 2012-09-21 US US14/347,547 patent/US20140377807A1/en not_active Abandoned
- 2012-09-21 IN IN2854CHN2014 patent/IN2014CN02854A/en unknown
- 2012-09-21 BR BR112014007174-8A patent/BR112014007174B1/pt not_active IP Right Cessation
- 2012-09-21 SG SG11201400936QA patent/SG11201400936QA/en unknown
- 2012-09-21 CA CA2849752A patent/CA2849752C/en active Active
- 2012-09-21 JP JP2013536233A patent/JP6186278B2/ja active Active
- 2012-09-21 WO PCT/JP2012/074239 patent/WO2013047372A1/ja not_active Ceased
- 2012-09-21 KR KR1020147010021A patent/KR101942608B1/ko not_active Expired - Fee Related
- 2012-09-21 SG SG10201602024YA patent/SG10201602024YA/en unknown
- 2012-09-21 AU AU2012317742A patent/AU2012317742B2/en not_active Ceased
- 2012-09-25 TW TW101135056A patent/TWI549963B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014115769A (ru) | 2015-10-27 |
| TW201321400A (zh) | 2013-06-01 |
| SG11201400936QA (en) | 2014-10-30 |
| EP2762485A1 (en) | 2014-08-06 |
| CA2849752C (en) | 2020-06-23 |
| EP2762485B1 (en) | 2018-08-01 |
| BR112014007174B1 (pt) | 2021-11-30 |
| KR101942608B1 (ko) | 2019-01-25 |
| IN2014CN02854A (enExample) | 2015-07-03 |
| TWI549963B (zh) | 2016-09-21 |
| AU2012317742A1 (en) | 2014-04-17 |
| KR20140091678A (ko) | 2014-07-22 |
| CA2849752A1 (en) | 2013-04-04 |
| AU2012317742B2 (en) | 2016-10-13 |
| SG10201602024YA (en) | 2016-04-28 |
| RU2605411C2 (ru) | 2016-12-20 |
| JPWO2013047372A1 (ja) | 2015-03-26 |
| BR112014007174A2 (pt) | 2017-04-04 |
| WO2013047372A1 (ja) | 2013-04-04 |
| EP2762485A4 (en) | 2015-06-24 |
| US20140377807A1 (en) | 2014-12-25 |
| CN104080796A (zh) | 2014-10-01 |
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| KR20140011357A (ko) | 시알릴 당쇄를 갖는 당펩티드의 제조방법, 당해 제조방법에 사용하는 시알릴 당쇄 부가 아미노산 유도체 및 당해 당펩티드 | |
| JP6186278B2 (ja) | Ncl法に適した、ポリペプチド断片の効率的な製造方法 | |
| JP5730197B2 (ja) | ペプチドチオエステル体の製造方法 | |
| SG186922A1 (en) | Compound for use in peptide synthesis | |
| US20050096456A1 (en) | Compounds comprising pseudo-amino acids | |
| Li | Chemical synthesis of proteins containing post‐translational modifications and PNA‐templated disulfide bond formation |
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