RU2605411C2 - Способ высокоэффективного получения полипептидного фрагмента, подходящего для ncl - Google Patents
Способ высокоэффективного получения полипептидного фрагмента, подходящего для ncl Download PDFInfo
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- RU2605411C2 RU2605411C2 RU2014115769/04A RU2014115769A RU2605411C2 RU 2605411 C2 RU2605411 C2 RU 2605411C2 RU 2014115769/04 A RU2014115769/04 A RU 2014115769/04A RU 2014115769 A RU2014115769 A RU 2014115769A RU 2605411 C2 RU2605411 C2 RU 2605411C2
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- HNKJADCVZUBCPG-UHFFFAOYSA-N thioanisole Chemical compound CSC1=CC=CC=C1 HNKJADCVZUBCPG-UHFFFAOYSA-N 0.000 description 1
- 125000000101 thioether group Chemical group 0.000 description 1
- 150000003587 threonine derivatives Chemical class 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5437—IL-13
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-210007 | 2011-09-26 | ||
| JP2011210007 | 2011-09-26 | ||
| PCT/JP2012/074239 WO2013047372A1 (ja) | 2011-09-26 | 2012-09-21 | Ｎｃｌ法に適した、ポリペプチド断片の効率的な製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014115769A RU2014115769A (ru) | 2015-10-27 |
| RU2605411C2 true RU2605411C2 (ru) | 2016-12-20 |
Family
ID=47995404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014115769/04A RU2605411C2 (ru) | 2011-09-26 | 2012-09-21 | Способ высокоэффективного получения полипептидного фрагмента, подходящего для ncl |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140377807A1 (enExample) |
| EP (1) | EP2762485B1 (enExample) |
| JP (1) | JP6186278B2 (enExample) |
| KR (1) | KR101942608B1 (enExample) |
| CN (1) | CN104080796A (enExample) |
| AU (1) | AU2012317742B2 (enExample) |
| BR (1) | BR112014007174B1 (enExample) |
| CA (1) | CA2849752C (enExample) |
| IN (1) | IN2014CN02854A (enExample) |
| RU (1) | RU2605411C2 (enExample) |
| SG (2) | SG11201400936QA (enExample) |
| TW (1) | TWI549963B (enExample) |
| WO (1) | WO2013047372A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3868401A1 (en) * | 2020-02-21 | 2021-08-25 | Assistance Publique Hôpitaux de Paris | Optimization of peptide-melanin binding |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| RU2529998C2 (ru) * | 2009-06-26 | 2014-10-10 | Глитек,Инк. | Способ получения тиоэфира пептида |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69521815T2 (de) | 1995-05-04 | 2002-04-04 | The Scripps Research Institute, La Jolla | Proteinsynthese mittels nativer chemischer ligation (07.01.97) |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| JP4607017B2 (ja) | 2003-07-28 | 2011-01-05 | 大塚化学株式会社 | アミノ化複合型糖鎖誘導体及びその製造方法 |
| WO2005095331A1 (ja) | 2004-03-31 | 2005-10-13 | Shionogi & Co., Ltd. | 糖鎖－ペプチド結合剤 |
| JP2007114454A (ja) | 2005-10-20 | 2007-05-10 | Yamaha Corp | マイクロレンズアレイとその製法 |
| CN101437836B (zh) | 2006-03-29 | 2013-07-24 | 株式会社糖锁工学研究所 | 肽的硫酯化合物的制造方法 |
| WO2008066902A2 (en) * | 2006-11-30 | 2008-06-05 | Nektar Therapeutics Al, Corporation | Method for preparing a polymer conjugate |
| JP2010150730A (ja) | 2008-12-25 | 2010-07-08 | Soichiro Hayashi | 中手指節関節運動制限具 |
| TW201031749A (en) * | 2009-02-10 | 2010-09-01 | Otsuka Chemical Co Ltd | IgG-Fc fragment and method for manufacturing the same |
-
2012
- 2012-09-21 EP EP12837234.9A patent/EP2762485B1/en active Active
- 2012-09-21 RU RU2014115769/04A patent/RU2605411C2/ru active
- 2012-09-21 CN CN201280057905.1A patent/CN104080796A/zh active Pending
- 2012-09-21 US US14/347,547 patent/US20140377807A1/en not_active Abandoned
- 2012-09-21 IN IN2854CHN2014 patent/IN2014CN02854A/en unknown
- 2012-09-21 BR BR112014007174-8A patent/BR112014007174B1/pt not_active IP Right Cessation
- 2012-09-21 SG SG11201400936QA patent/SG11201400936QA/en unknown
- 2012-09-21 CA CA2849752A patent/CA2849752C/en active Active
- 2012-09-21 JP JP2013536233A patent/JP6186278B2/ja active Active
- 2012-09-21 WO PCT/JP2012/074239 patent/WO2013047372A1/ja not_active Ceased
- 2012-09-21 KR KR1020147010021A patent/KR101942608B1/ko not_active Expired - Fee Related
- 2012-09-21 SG SG10201602024YA patent/SG10201602024YA/en unknown
- 2012-09-21 AU AU2012317742A patent/AU2012317742B2/en not_active Ceased
- 2012-09-25 TW TW101135056A patent/TWI549963B/zh not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| RU2529998C2 (ru) * | 2009-06-26 | 2014-10-10 | Глитек,Инк. | Способ получения тиоэфира пептида |
Non-Patent Citations (2)
| Title |
|---|
| RICHARDSON JONATHAN P ET AL, "Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation", ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, 2008, vol. 6, no. 21, * |
| RICHARDSON JONATHAN P ET AL, "Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation", ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, 2008, vol. 6, no. 21, PAGE 3977 -; 3982. * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6186278B2 (ja) | 2017-08-23 |
| RU2014115769A (ru) | 2015-10-27 |
| TW201321400A (zh) | 2013-06-01 |
| SG11201400936QA (en) | 2014-10-30 |
| EP2762485A1 (en) | 2014-08-06 |
| CA2849752C (en) | 2020-06-23 |
| EP2762485B1 (en) | 2018-08-01 |
| BR112014007174B1 (pt) | 2021-11-30 |
| KR101942608B1 (ko) | 2019-01-25 |
| IN2014CN02854A (enExample) | 2015-07-03 |
| TWI549963B (zh) | 2016-09-21 |
| AU2012317742A1 (en) | 2014-04-17 |
| KR20140091678A (ko) | 2014-07-22 |
| CA2849752A1 (en) | 2013-04-04 |
| AU2012317742B2 (en) | 2016-10-13 |
| SG10201602024YA (en) | 2016-04-28 |
| JPWO2013047372A1 (ja) | 2015-03-26 |
| BR112014007174A2 (pt) | 2017-04-04 |
| WO2013047372A1 (ja) | 2013-04-04 |
| EP2762485A4 (en) | 2015-06-24 |
| US20140377807A1 (en) | 2014-12-25 |
| CN104080796A (zh) | 2014-10-01 |
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