KR101942608B1 - Ncl법에 적합한 폴리펩티드 단편의 효율적인 제조방법 - Google Patents

Ncl법에 적합한 폴리펩티드 단편의 효율적인 제조방법 Download PDF

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Publication number
KR101942608B1
KR101942608B1 KR1020147010021A KR20147010021A KR101942608B1 KR 101942608 B1 KR101942608 B1 KR 101942608B1 KR 1020147010021 A KR1020147010021 A KR 1020147010021A KR 20147010021 A KR20147010021 A KR 20147010021A KR 101942608 B1 KR101942608 B1 KR 101942608B1
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KR
South Korea
Prior art keywords
polypeptide fragment
group
terminal side
polypeptide
sugar chain
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Expired - Fee Related
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KR1020147010021A
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English (en)
Korean (ko)
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KR20140091678A (ko
Inventor
야스히로 카지하라
료 오카모토
모토하루 기무라
카즈유키 이시이
Original Assignee
가부시키가이샤 도우사 고가쿠 겐큐쇼
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Publication of KR20140091678A publication Critical patent/KR20140091678A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5437—IL-13
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020147010021A 2011-09-26 2012-09-21 Ncl법에 적합한 폴리펩티드 단편의 효율적인 제조방법 Expired - Fee Related KR101942608B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2011-210007 2011-09-26
JP2011210007 2011-09-26
PCT/JP2012/074239 WO2013047372A1 (ja) 2011-09-26 2012-09-21 Ｎｃｌ法に適した、ポリペプチド断片の効率的な製造方法

Publications (2)

Publication Number Publication Date
KR20140091678A KR20140091678A (ko) 2014-07-22
KR101942608B1 true KR101942608B1 (ko) 2019-01-25

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KR1020147010021A Expired - Fee Related KR101942608B1 (ko) 2011-09-26 2012-09-21 Ncl법에 적합한 폴리펩티드 단편의 효율적인 제조방법

Country Status (13)

Country Link
US (1) US20140377807A1 (enExample)
EP (1) EP2762485B1 (enExample)
JP (1) JP6186278B2 (enExample)
KR (1) KR101942608B1 (enExample)
CN (1) CN104080796A (enExample)
AU (1) AU2012317742B2 (enExample)
BR (1) BR112014007174B1 (enExample)
CA (1) CA2849752C (enExample)
IN (1) IN2014CN02854A (enExample)
RU (1) RU2605411C2 (enExample)
SG (2) SG10201602024YA (enExample)
TW (1) TWI549963B (enExample)
WO (1) WO2013047372A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3868401A1 (en) * 2020-02-21 2021-08-25 Assistance Publique Hôpitaux de Paris Optimization of peptide-melanin binding

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009242372A (ja) * 2008-03-11 2009-10-22 Yokohama City Univ 均一な糖鎖構造を有するエリスロポエチン誘導体
CA2766040A1 (en) 2009-06-26 2010-12-29 Otsuka Chemical Co., Ltd. Process for production of peptide thioester

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2218620C (en) 1995-05-04 2007-02-27 Stephen B. H. Kent Synthesis of proteins by native chemical ligation
US7943763B2 (en) 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
TWI325430B (en) 2003-07-28 2010-06-01 Yasuhiro Kajihara Aminated complex type sugar chain derivative and its production method
JPWO2005095331A1 (ja) 2004-03-31 2008-02-21 塩野義製薬株式会社 糖鎖−ペプチド結合剤
JP2007114454A (ja) 2005-10-20 2007-05-10 Yamaha Corp マイクロレンズアレイとその製法
CA2647867C (en) 2006-03-29 2015-11-03 Otsuka Chemical Co., Ltd. Method for production of peptide thioester compound
MX2009005780A (es) * 2006-11-30 2009-06-10 Nektar Therapeutics Al Corp Metodo para preparar un conjugado de polimeros.
JP2010150730A (ja) 2008-12-25 2010-07-08 Soichiro Hayashi 中手指節関節運動制限具
TW201031749A (en) * 2009-02-10 2010-09-01 Otsuka Chemical Co Ltd IgG-Fc fragment and method for manufacturing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009242372A (ja) * 2008-03-11 2009-10-22 Yokohama City Univ 均一な糖鎖構造を有するエリスロポエチン誘導体
CA2766040A1 (en) 2009-06-26 2010-12-29 Otsuka Chemical Co., Ltd. Process for production of peptide thioester

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J Am Chem Soc.,128(20):6640-6646(2006.5.)

Also Published As

Publication number Publication date
CA2849752A1 (en) 2013-04-04
TW201321400A (zh) 2013-06-01
IN2014CN02854A (enExample) 2015-07-03
BR112014007174B1 (pt) 2021-11-30
CN104080796A (zh) 2014-10-01
BR112014007174A2 (pt) 2017-04-04
AU2012317742A1 (en) 2014-04-17
SG10201602024YA (en) 2016-04-28
JPWO2013047372A1 (ja) 2015-03-26
SG11201400936QA (en) 2014-10-30
EP2762485B1 (en) 2018-08-01
KR20140091678A (ko) 2014-07-22
RU2014115769A (ru) 2015-10-27
AU2012317742B2 (en) 2016-10-13
CA2849752C (en) 2020-06-23
TWI549963B (zh) 2016-09-21
EP2762485A4 (en) 2015-06-24
JP6186278B2 (ja) 2017-08-23
EP2762485A1 (en) 2014-08-06
RU2605411C2 (ru) 2016-12-20
WO2013047372A1 (ja) 2013-04-04
US20140377807A1 (en) 2014-12-25

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