TWI466690B - 塗膜錠劑調配物 - Google Patents

塗膜錠劑調配物 Download PDF

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Publication number
TWI466690B
TWI466690B TW99138396A TW99138396A TWI466690B TW I466690 B TWI466690 B TW I466690B TW 99138396 A TW99138396 A TW 99138396A TW 99138396 A TW99138396 A TW 99138396A TW I466690 B TWI466690 B TW I466690B
Authority
TW
Taiwan
Prior art keywords
weight
composition
crospovidone
intragranular
component
Prior art date
Application number
TW99138396A
Other languages
English (en)
Chinese (zh)
Other versions
TW201138774A (en
Inventor
Muhammad Ashraf
Krishnendu Ghosh
Chimanlall Goolcharran
Mainuddin Mahmud
Arwinder Singh Nagi
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43478191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI466690(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of TW201138774A publication Critical patent/TW201138774A/zh
Application granted granted Critical
Publication of TWI466690B publication Critical patent/TWI466690B/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW99138396A 2009-11-09 2010-11-08 塗膜錠劑調配物 TWI466690B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25940309P 2009-11-09 2009-11-09

Publications (2)

Publication Number Publication Date
TW201138774A TW201138774A (en) 2011-11-16
TWI466690B true TWI466690B (zh) 2015-01-01

Family

ID=43478191

Family Applications (1)

Application Number Title Priority Date Filing Date
TW99138396A TWI466690B (zh) 2009-11-09 2010-11-08 塗膜錠劑調配物

Country Status (23)

Country Link
US (2) US8518446B2 (https=)
EP (4) EP4066821B1 (https=)
JP (3) JP5835883B2 (https=)
CN (2) CN102724970B (https=)
AR (2) AR078952A1 (https=)
AU (1) AU2010316683B2 (https=)
CA (1) CA2780428C (https=)
CY (1) CY1122330T1 (https=)
DK (2) DK2498756T4 (https=)
ES (3) ES2757882T5 (https=)
FI (3) FI4066821T3 (https=)
FR (1) FR25C1035I1 (https=)
HR (2) HRP20192026T4 (https=)
HU (3) HUE046606T2 (https=)
LT (3) LT4066821T (https=)
NZ (1) NZ599763A (https=)
PL (2) PL4066821T3 (https=)
PT (2) PT4066821T (https=)
RS (2) RS59599B2 (https=)
SI (2) SI2498756T2 (https=)
SM (2) SMT202500153T1 (https=)
TW (1) TWI466690B (https=)
WO (1) WO2011055303A1 (https=)

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US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
US9439897B2 (en) 2007-11-06 2016-09-13 Immunolight, Llc Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
ES2692769T3 (es) 2008-06-17 2018-12-05 Wyeth Llc Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina
CN105147713A (zh) 2008-08-04 2015-12-16 惠氏有限责任公司 4-苯胺基-3-氰基喹啉和卡培他滨的抗肿瘤组合
SG174382A1 (en) 2009-04-06 2011-11-28 Wyeth Llc Treatment regimen utilizing neratinib for breast cancer
CN102724962B (zh) * 2009-11-09 2017-05-17 惠氏有限责任公司 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途
AU2010316683B2 (en) * 2009-11-09 2015-10-08 Wyeth Llc Tablet formulations of neratinib maleate
HK1203412A1 (en) 2011-12-28 2015-10-30 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
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US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
CN105073728A (zh) 2013-03-15 2015-11-18 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
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CN106913529B (zh) * 2015-12-24 2020-12-04 江苏恒瑞医药股份有限公司 一种来那替尼或其可药用盐药物组合物的制备方法
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KR20190140011A (ko) * 2017-04-28 2019-12-18 아사나 바이오사이언시스 엘엘씨 아토피성 피부염을 치료하고, 활성 약학적 성분의 안정성을 개선하기 위한 제형물, 방법, 키트, 및 투여형
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US20080268034A1 (en) * 2005-01-07 2008-10-30 Girish Karanth Solid Oral Dosage Forms of Ziprasidone Containing Colloidal Silicone Dioxide

Also Published As

Publication number Publication date
DK4066821T3 (da) 2025-04-14
CN102724970A (zh) 2012-10-10
ES2757882T5 (es) 2023-05-10
ES2757882T3 (es) 2020-04-30
HUE071632T2 (hu) 2025-09-28
RS66797B1 (sr) 2025-06-30
TW201138774A (en) 2011-11-16
LT4066821T (lt) 2025-05-12
US8790708B2 (en) 2014-07-29
US8518446B2 (en) 2013-08-27
SI2498756T2 (sl) 2023-04-28
EP4570242A3 (en) 2025-08-20
EP2498756A1 (en) 2012-09-19
EP2498756B1 (en) 2019-09-04
HRP20192026T4 (hr) 2023-03-31
DK2498756T3 (da) 2019-11-25
HRP20250604T1 (hr) 2025-07-18
DK2498756T4 (da) 2023-03-20
CN103893140B (zh) 2016-06-01
RS59599B2 (sr) 2023-03-31
ES2998766T3 (en) 2025-02-21
JP2015091882A (ja) 2015-05-14
NZ599763A (en) 2014-06-27
US20140004184A1 (en) 2014-01-02
HUS2500035I1 (hu) 2025-09-28
EP4570242A2 (en) 2025-06-18
ES3029208T3 (en) 2025-06-23
FR25C1035I1 (fr) 2025-11-21
LTPA2025531I1 (https=) 2025-09-10
SI4066821T1 (sl) 2025-06-30
AR114143A2 (es) 2020-07-29
CA2780428A1 (en) 2011-05-12
SI2498756T1 (sl) 2020-01-31
PT4066821T (pt) 2025-06-03
EP4066821A1 (en) 2022-10-05
LT2498756T (lt) 2019-12-10
PL2498756T3 (pl) 2020-03-31
HUE046606T2 (hu) 2020-03-30
CN103893140A (zh) 2014-07-02
JP5835883B2 (ja) 2015-12-24
EP2498756B2 (en) 2023-02-15
CA2780428C (en) 2018-02-13
PL4066821T3 (pl) 2025-08-11
EP4066821B1 (en) 2025-03-05
AU2010316683B2 (en) 2015-10-08
PL2498756T5 (pl) 2023-04-17
WO2011055303A1 (en) 2011-05-12
US20110111018A1 (en) 2011-05-12
CY1122330T1 (el) 2021-01-27
FI2498756T4 (fi) 2023-03-22
SMT202500153T1 (it) 2025-05-12
RS59599B1 (sr) 2020-01-31
JP2011098964A (ja) 2011-05-19
HRP20192026T1 (hr) 2020-02-07
SMT201900632T1 (it) 2020-01-14
EP3566697B1 (en) 2024-09-11
AR078952A1 (es) 2011-12-14
FI4066821T3 (fi) 2025-05-13
JP2017075192A (ja) 2017-04-20
CN102724970B (zh) 2014-06-25
PT2498756T (pt) 2019-11-26
AU2010316683A1 (en) 2012-05-24
FIC20250029I1 (fi) 2025-08-29
EP3566697A1 (en) 2019-11-13

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