TWI383811B - 具有黏著層之經皮治療系統，將該系統之支撐層加以聚矽氧化的方法以及該支撐層的用途 - Google Patents

具有黏著層之經皮治療系統，將該系統之支撐層加以聚矽氧化的方法以及該支撐層的用途 Download PDF

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Publication number
TWI383811B
TWI383811B TW094130154A TW94130154A TWI383811B TW I383811 B TWI383811 B TW I383811B TW 094130154 A TW094130154 A TW 094130154A TW 94130154 A TW94130154 A TW 94130154A TW I383811 B TWI383811 B TW I383811B
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TW
Taiwan
Prior art keywords
layer
support layer
adhesive
transdermal therapeutic
therapeutic system
Prior art date
Application number
TW094130154A
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English (en)
Chinese (zh)
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TW200621319A (en
Inventor
莫勒 瓦特
雷昂哈德 約翰斯
Original Assignee
洛曼治療系統股份有限公司
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Publication of TW200621319A publication Critical patent/TW200621319A/zh
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Publication of TWI383811B publication Critical patent/TWI383811B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/023—Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer
    • A61F13/0253—Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the adhesive material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
TW094130154A 2004-09-13 2005-09-02 具有黏著層之經皮治療系統，將該系統之支撐層加以聚矽氧化的方法以及該支撐層的用途 TWI383811B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004044578A DE102004044578A1 (de) 2004-09-13 2004-09-13 Transdermales therapeutisches System mit einer Haftschicht, Verfahren zum Silikonisieren einer Rückschicht des Systems und Verwendung der Rückschicht

Publications (2)

Publication Number Publication Date
TW200621319A TW200621319A (en) 2006-07-01
TWI383811B true TWI383811B (zh) 2013-02-01

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TW094130154A TWI383811B (zh) 2004-09-13 2005-09-02 具有黏著層之經皮治療系統，將該系統之支撐層加以聚矽氧化的方法以及該支撐層的用途

Country Status (25)

Country Link
US (2) US9226903B2 (enExample)
EP (2) EP2529732B1 (enExample)
JP (1) JP4921371B2 (enExample)
KR (1) KR101297903B1 (enExample)
CN (2) CN102755305A (enExample)
AR (1) AR050621A1 (enExample)
AU (1) AU2005284436B2 (enExample)
BR (1) BRPI0515270B8 (enExample)
CA (1) CA2578534C (enExample)
CY (2) CY1113997T1 (enExample)
DE (1) DE102004044578A1 (enExample)
DK (2) DK1791533T3 (enExample)
ES (2) ES2406958T3 (enExample)
IL (1) IL181337A (enExample)
LT (1) LT2529732T (enExample)
MX (1) MX2007002966A (enExample)
NZ (1) NZ553485A (enExample)
PH (1) PH12012501165A1 (enExample)
PL (2) PL1791533T3 (enExample)
PT (2) PT2529732T (enExample)
RU (1) RU2398567C2 (enExample)
SI (2) SI1791533T1 (enExample)
TW (1) TWI383811B (enExample)
WO (1) WO2006029740A2 (enExample)
ZA (1) ZA200701138B (enExample)

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CA2580329C (en) 2004-09-13 2015-01-06 Chrono Therapeutics Inc. Biosynchronous transdermal drug delivery
US8518926B2 (en) * 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
ES2379117T3 (es) * 2006-05-16 2012-04-20 Knopp Neurosciences, Inc. Composiciones de R(+) y S(-) pramipexol y métodos de utilización de las mismas
US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
WO2008113056A2 (en) 2007-03-14 2008-09-18 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
CN102186350A (zh) * 2008-08-19 2011-09-14 诺普神经科学股份有限公司 使用(r)-普拉克索的组合物与方法
US20110009460A1 (en) * 2009-06-19 2011-01-13 Valentin Gribkoff Compositions and methods for treating amyotrophic lateral sclerosis
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
KR101850161B1 (ko) 2012-05-17 2018-04-19 도레이첨단소재 주식회사 경피흡수제에 적합하게 사용될 수 있는 릴리즈 라이너 및 그 제조방법
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
SMT202100119T1 (it) 2013-07-12 2021-05-07 Knopp Biosciences Llc Trattamento dei livelli elevati di eosinofili e/o basofili
AU2014306597B2 (en) 2013-08-13 2018-05-17 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
EP3038467B1 (en) 2013-08-13 2020-07-29 Knopp Biosciences LLC Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
US9827206B2 (en) * 2013-09-24 2017-11-28 Zodiac Coating Method for producing an adhesive material for medical application
EP2921184A1 (de) * 2014-03-19 2015-09-23 LTS LOHMANN Therapie-Systeme AG Überpflaster mit verbesserter Verträglichkeit und einer langen Haftungsdauer und Verfahren zu seiner Herstellung
CA2974324A1 (en) 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system

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CN1356895A (zh) * 1999-07-02 2002-07-03 Lts勒曼治疗系统股份公司 以聚硅氧烷及亲两性溶剂为基础的微贮存系统

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Publication number Publication date
DK2529732T3 (en) 2017-09-18
IL181337A (en) 2014-09-30
CN101018545A (zh) 2007-08-15
RU2398567C2 (ru) 2010-09-10
CY1113997T1 (el) 2016-07-27
BRPI0515270B8 (pt) 2021-07-27
ES2406958T3 (es) 2013-06-10
AU2005284436B2 (en) 2011-02-17
BRPI0515270A (pt) 2008-07-15
CA2578534A1 (en) 2006-03-23
US20080026043A1 (en) 2008-01-31
EP2529732B1 (de) 2017-06-21
EP2529732A1 (de) 2012-12-05
CY1120228T1 (el) 2018-12-12
US10034841B2 (en) 2018-07-31
TW200621319A (en) 2006-07-01
JP4921371B2 (ja) 2012-04-25
ZA200701138B (en) 2008-08-27
WO2006029740A2 (de) 2006-03-23
PT2529732T (pt) 2017-07-17
SI1791533T1 (sl) 2013-05-31
DE102004044578A1 (de) 2006-03-30
CN102755305A (zh) 2012-10-31
WO2006029740A3 (de) 2006-06-22
AU2005284436A1 (en) 2006-03-23
PL2529732T3 (pl) 2017-12-29
NZ553485A (en) 2010-06-25
IL181337A0 (en) 2007-07-04
JP2008512411A (ja) 2008-04-24
CA2578534C (en) 2013-03-19
US20160074336A1 (en) 2016-03-17
ES2634439T3 (es) 2017-09-27
EP1791533B1 (de) 2013-03-06
DK1791533T3 (da) 2013-06-10
PL1791533T3 (pl) 2013-08-30
LT2529732T (lt) 2017-09-11
PT1791533E (pt) 2013-05-07
BRPI0515270B1 (pt) 2018-11-06
EP1791533A2 (de) 2007-06-06
KR20070053244A (ko) 2007-05-23
PH12012501165A1 (en) 2013-09-02
RU2007113674A (ru) 2008-10-27
AR050621A1 (es) 2006-11-08
MX2007002966A (es) 2007-04-27
US9226903B2 (en) 2016-01-05
SI2529732T1 (sl) 2017-10-30
KR101297903B1 (ko) 2013-08-22

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