KR101297903B1 - 접착제 층을 포함하는 경피 치료 시스템, 상기 시스템의 배면 층을 실리콘화시키는 방법 및 상기 배면 층의 용도 - Google Patents

접착제 층을 포함하는 경피 치료 시스템, 상기 시스템의 배면 층을 실리콘화시키는 방법 및 상기 배면 층의 용도 Download PDF

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Publication number
KR101297903B1
KR101297903B1 KR1020077005735A KR20077005735A KR101297903B1 KR 101297903 B1 KR101297903 B1 KR 101297903B1 KR 1020077005735 A KR1020077005735 A KR 1020077005735A KR 20077005735 A KR20077005735 A KR 20077005735A KR 101297903 B1 KR101297903 B1 KR 101297903B1
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KR
South Korea
Prior art keywords
layer
transdermal therapeutic
group
back layer
adhesive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1020077005735A
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English (en)
Korean (ko)
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KR20070053244A (ko
Inventor
월터 뮐러
요하네스 레온하드
Original Assignee
에르테에스 로만 테라피-시스테메 아게
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Publication of KR20070053244A publication Critical patent/KR20070053244A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/023—Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer
    • A61F13/0253—Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the adhesive material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
KR1020077005735A 2004-09-13 2005-09-06 접착제 층을 포함하는 경피 치료 시스템, 상기 시스템의 배면 층을 실리콘화시키는 방법 및 상기 배면 층의 용도 Expired - Lifetime KR101297903B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004044578.8 2004-09-13
DE102004044578A DE102004044578A1 (de) 2004-09-13 2004-09-13 Transdermales therapeutisches System mit einer Haftschicht, Verfahren zum Silikonisieren einer Rückschicht des Systems und Verwendung der Rückschicht
PCT/EP2005/009547 WO2006029740A2 (de) 2004-09-13 2005-09-06 Transdermales therapeutisches system mit einer haftschicht, verfahren zum silikonisieren einer rückschicht des systems und verwendung der rückschicht

Publications (2)

Publication Number Publication Date
KR20070053244A KR20070053244A (ko) 2007-05-23
KR101297903B1 true KR101297903B1 (ko) 2013-08-22

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KR1020077005735A Expired - Lifetime KR101297903B1 (ko) 2004-09-13 2005-09-06 접착제 층을 포함하는 경피 치료 시스템, 상기 시스템의 배면 층을 실리콘화시키는 방법 및 상기 배면 층의 용도

Country Status (25)

Country Link
US (2) US9226903B2 (enExample)
EP (2) EP1791533B1 (enExample)
JP (1) JP4921371B2 (enExample)
KR (1) KR101297903B1 (enExample)
CN (2) CN101018545A (enExample)
AR (1) AR050621A1 (enExample)
AU (1) AU2005284436B2 (enExample)
BR (1) BRPI0515270B8 (enExample)
CA (1) CA2578534C (enExample)
CY (2) CY1113997T1 (enExample)
DE (1) DE102004044578A1 (enExample)
DK (2) DK2529732T3 (enExample)
ES (2) ES2634439T3 (enExample)
IL (1) IL181337A (enExample)
LT (1) LT2529732T (enExample)
MX (1) MX2007002966A (enExample)
NZ (1) NZ553485A (enExample)
PH (1) PH12012501165A1 (enExample)
PL (2) PL2529732T3 (enExample)
PT (2) PT1791533E (enExample)
RU (1) RU2398567C2 (enExample)
SI (2) SI1791533T1 (enExample)
TW (1) TWI383811B (enExample)
WO (1) WO2006029740A2 (enExample)
ZA (1) ZA200701138B (enExample)

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US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US8518926B2 (en) * 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
CN102160865A (zh) 2006-05-16 2011-08-24 诺普神经科学股份有限公司 R(+)和s(-)普拉克索的组合物以及使用该组合物的方法
US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US8519148B2 (en) 2007-03-14 2013-08-27 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
JP2012500283A (ja) 2008-08-19 2012-01-05 ノップ ニューロサイエンシーズ、インク． （ｒ）−プラミペキソールを使用した組成物並びにその方法
AU2010262970A1 (en) * 2009-06-19 2012-01-12 Knopp Neurosciences, Inc. Compositions and methods for treating amyotrophic lateral sclerosis
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
KR101850161B1 (ko) 2012-05-17 2018-04-19 도레이첨단소재 주식회사 경피흡수제에 적합하게 사용될 수 있는 릴리즈 라이너 및 그 제조방법
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
RS67279B1 (sr) 2013-07-12 2025-10-31 Areteia Therapeutics Inc Lečenje povišenih nivoa eozinofila i/ili bazofila
EP3033081B1 (en) 2013-08-13 2021-05-12 Knopp Biosciences LLC Compositions and methods for treating chronic urticaria
ES2813674T3 (es) 2013-08-13 2021-03-24 Knopp Biosciences Llc Composiciones y métodos para el tratamiento de trastornos de células plasmáticas y trastornos prolinfocíticos de células b
JP2016537039A (ja) * 2013-09-24 2016-12-01 ゾディアック コーティング 医療用接着性材料の製造方法
EP2921184A1 (de) * 2014-03-19 2015-09-23 LTS LOHMANN Therapie-Systeme AG Überpflaster mit verbesserter Verträglichkeit und einer langen Haftungsdauer und Verfahren zu seiner Herstellung
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
JP2022507660A (ja) 2018-11-16 2022-01-18 モーニングサイド ベンチャー インベストメンツ リミテッド 温度によって調節される経皮薬剤送達システム

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WO1999011265A1 (de) 1997-09-04 1999-03-11 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system mit dem wirkstoff scopolaminbase
WO2001074338A1 (de) 2000-03-30 2001-10-11 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system zur abgabe von lerisetron
US20040057985A1 (en) 2000-12-06 2004-03-25 Stefan Bracht Transdermal therapeutic system comprising the active ingredient oxybutynin
WO2004069286A2 (de) 2003-02-07 2004-08-19 Lts Lohmann Therapie-Systeme Ag Für die wärmeanwendung zur beschleunigung der permeation von wirkstoffen geeignetes transdermales therapeutisches system und seine verwendung

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Publication number Priority date Publication date Assignee Title
WO1999011265A1 (de) 1997-09-04 1999-03-11 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system mit dem wirkstoff scopolaminbase
WO2001074338A1 (de) 2000-03-30 2001-10-11 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches system zur abgabe von lerisetron
US20040057985A1 (en) 2000-12-06 2004-03-25 Stefan Bracht Transdermal therapeutic system comprising the active ingredient oxybutynin
WO2004069286A2 (de) 2003-02-07 2004-08-19 Lts Lohmann Therapie-Systeme Ag Für die wärmeanwendung zur beschleunigung der permeation von wirkstoffen geeignetes transdermales therapeutisches system und seine verwendung

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Publication number Publication date
BRPI0515270B1 (pt) 2018-11-06
US9226903B2 (en) 2016-01-05
PL2529732T3 (pl) 2017-12-29
DK1791533T3 (da) 2013-06-10
BRPI0515270B8 (pt) 2021-07-27
CY1113997T1 (el) 2016-07-27
ES2634439T3 (es) 2017-09-27
CN101018545A (zh) 2007-08-15
JP2008512411A (ja) 2008-04-24
WO2006029740A3 (de) 2006-06-22
AR050621A1 (es) 2006-11-08
SI2529732T1 (sl) 2017-10-30
DE102004044578A1 (de) 2006-03-30
EP2529732A1 (de) 2012-12-05
PT2529732T (pt) 2017-07-17
PL1791533T3 (pl) 2013-08-30
CA2578534A1 (en) 2006-03-23
AU2005284436B2 (en) 2011-02-17
PT1791533E (pt) 2013-05-07
US20080026043A1 (en) 2008-01-31
EP1791533A2 (de) 2007-06-06
AU2005284436A1 (en) 2006-03-23
PH12012501165A1 (en) 2013-09-02
MX2007002966A (es) 2007-04-27
TW200621319A (en) 2006-07-01
ES2406958T3 (es) 2013-06-10
RU2398567C2 (ru) 2010-09-10
CN102755305A (zh) 2012-10-31
BRPI0515270A (pt) 2008-07-15
TWI383811B (zh) 2013-02-01
RU2007113674A (ru) 2008-10-27
IL181337A0 (en) 2007-07-04
EP1791533B1 (de) 2013-03-06
LT2529732T (lt) 2017-09-11
EP2529732B1 (de) 2017-06-21
SI1791533T1 (sl) 2013-05-31
DK2529732T3 (en) 2017-09-18
CA2578534C (en) 2013-03-19
CY1120228T1 (el) 2018-12-12
WO2006029740A2 (de) 2006-03-23
KR20070053244A (ko) 2007-05-23
ZA200701138B (en) 2008-08-27
US10034841B2 (en) 2018-07-31
US20160074336A1 (en) 2016-03-17
IL181337A (en) 2014-09-30
NZ553485A (en) 2010-06-25
JP4921371B2 (ja) 2012-04-25

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