TWI342393B - - Google Patents
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- TWI342393B TWI342393B TW93116466A TW93116466A TWI342393B TW I342393 B TWI342393 B TW I342393B TW 93116466 A TW93116466 A TW 93116466A TW 93116466 A TW93116466 A TW 93116466A TW I342393 B TWI342393 B TW I342393B
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- 238000000034 method Methods 0.000 claims description 118
- 239000003814 drug Substances 0.000 claims description 82
- 229940079593 drug Drugs 0.000 claims description 51
- 239000003795 chemical substances by application Substances 0.000 claims description 45
- 238000001514 detection method Methods 0.000 claims description 35
- 238000004090 dissolution Methods 0.000 claims description 27
- 238000004128 high performance liquid chromatography Methods 0.000 claims description 26
- 238000011156 evaluation Methods 0.000 claims description 21
- 239000008177 pharmaceutical agent Substances 0.000 claims description 21
- 238000002360 preparation method Methods 0.000 claims description 13
- 238000007726 management method Methods 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 4
- 238000004587 chromatography analysis Methods 0.000 claims description 3
- 238000007906 compression Methods 0.000 claims description 3
- 230000006835 compression Effects 0.000 claims description 3
- 229910052770 Uranium Inorganic materials 0.000 claims 1
- 230000036962 time dependent Effects 0.000 claims 1
- JFALSRSLKYAFGM-UHFFFAOYSA-N uranium(0) Chemical compound [U] JFALSRSLKYAFGM-UHFFFAOYSA-N 0.000 claims 1
- 238000005259 measurement Methods 0.000 description 9
- 238000010828 elution Methods 0.000 description 6
- 238000013144 data compression Methods 0.000 description 5
- 238000009826 distribution Methods 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 244000037364 Cinnamomum aromaticum Species 0.000 description 4
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 244000242564 Osmanthus fragrans Species 0.000 description 1
- 235000019083 Osmanthus fragrans Nutrition 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- ALSPKRWQCLSJLV-UHFFFAOYSA-N azanium;acetic acid;acetate Chemical compound [NH4+].CC(O)=O.CC([O-])=O ALSPKRWQCLSJLV-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 239000006249 magnetic particle Substances 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 238000011045 prefiltration Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000007614 solvation Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW93116466A TW200540415A (en) | 2004-06-08 | 2004-06-08 | Multi-component medicine evaluation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW93116466A TW200540415A (en) | 2004-06-08 | 2004-06-08 | Multi-component medicine evaluation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200540415A TW200540415A (en) | 2005-12-16 |
| TWI342393B true TWI342393B (de) | 2011-05-21 |
Family
ID=45074833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW93116466A TW200540415A (en) | 2004-06-08 | 2004-06-08 | Multi-component medicine evaluation method |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TW200540415A (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105738519A (zh) * | 2016-02-26 | 2016-07-06 | 辽宁中医药大学 | 一种基于量效色卡的气滞胃痛颗粒抗溃疡质量控制方法 |
-
2004
- 2004-06-08 TW TW93116466A patent/TW200540415A/zh not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105738519A (zh) * | 2016-02-26 | 2016-07-06 | 辽宁中医药大学 | 一种基于量效色卡的气滞胃痛颗粒抗溃疡质量控制方法 |
| CN105738519B (zh) * | 2016-02-26 | 2018-03-06 | 辽宁中医药大学 | 一种基于量效色卡的气滞胃痛颗粒抗溃疡质量控制方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW200540415A (en) | 2005-12-16 |
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| MK4A | Expiration of patent term of an invention patent |