TWI341212B - Antiinflammatory and pain-relieving agent for external use - Google Patents

Antiinflammatory and pain-relieving agent for external use

Info

Publication number
TWI341212B
TWI341212B TW094119781A TW94119781A TWI341212B TW I341212 B TWI341212 B TW I341212B TW 094119781 A TW094119781 A TW 094119781A TW 94119781 A TW94119781 A TW 94119781A TW I341212 B TWI341212 B TW I341212B
Authority
TW
Taiwan
Prior art keywords
antiinflammatory
pain
external use
relieving agent
relieving
Prior art date
Application number
TW094119781A
Other languages
English (en)
Other versions
TW200602031A (en
Inventor
Youichi Kawamura
Yusuke Honda
Original Assignee
Hisamitsu Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co filed Critical Hisamitsu Pharmaceutical Co
Publication of TW200602031A publication Critical patent/TW200602031A/zh
Application granted granted Critical
Publication of TWI341212B publication Critical patent/TWI341212B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
TW094119781A 2004-06-15 2005-06-15 Antiinflammatory and pain-relieving agent for external use TWI341212B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004176722 2004-06-15

Publications (2)

Publication Number Publication Date
TW200602031A TW200602031A (en) 2006-01-16
TWI341212B true TWI341212B (en) 2011-05-01

Family

ID=35509462

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094119781A TWI341212B (en) 2004-06-15 2005-06-15 Antiinflammatory and pain-relieving agent for external use

Country Status (6)

Country Link
US (2) US7928144B2 (zh)
EP (1) EP1767218B1 (zh)
JP (1) JP4990617B2 (zh)
ES (1) ES2590258T3 (zh)
TW (1) TWI341212B (zh)
WO (1) WO2005123136A1 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI403333B (zh) * 2005-02-25 2013-08-01 Hisamitsu Pharmaceutical Co 含非類固醇系消炎鎮痛劑之外用經皮製劑
EP2025337B1 (en) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
WO2007102243A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
JP5160409B2 (ja) * 2006-03-08 2013-03-13 日本農薬株式会社 外用の医薬組成物
JP5078303B2 (ja) * 2006-09-15 2012-11-21 東光薬品工業株式会社 消炎鎮痛クリーム製剤及びその製造方法
EP2191826B1 (en) 2007-09-05 2017-03-08 Pola Pharma Inc. Pharmaceutical composition
EP2191827B1 (en) 2007-09-05 2013-10-30 Pola Pharma Inc. Antifungal composition
EP2191828B1 (en) 2007-09-05 2016-08-10 Pola Pharma Inc. Antifungal pharmaceutical composition
JP5301205B2 (ja) * 2008-05-28 2013-09-25 東興薬品工業株式会社 ゲル軟膏組成物
JP2010120912A (ja) * 2008-11-21 2010-06-03 Lead Chemical Co Ltd ５−メチル−１−フェニル−２−（１ｈ）−ピリドン含有貼付剤
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
KR101409789B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
JP5430601B2 (ja) * 2011-04-01 2014-03-05 マルホ株式会社 非エアゾール式フォーム剤用組成物
US20140329779A1 (en) * 2012-01-26 2014-11-06 Product And Technology Partners Llc Clear solid sticks with solubilized pharmaceutical agents
US8822537B2 (en) * 2012-09-27 2014-09-02 Achelios Therapeutics, Inc. Topical ketoprofen composition
EP2934458B2 (en) 2012-12-20 2023-02-22 Unilever Global IP Limited Eutectic mixtures in personal care compositions
BR112016017949B1 (pt) * 2014-02-27 2023-02-07 Hisamitsu Pharmaceutical Co., Inc Emplastro de gel contendo cetoprofeno
CN105434350A (zh) * 2015-12-24 2016-03-30 中国药科大学 一种双氯芬酸钠冰冻复乳经皮给药制剂及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US4954332A (en) * 1987-10-22 1990-09-04 The Procter & Gamble Company Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent
JPH05178763A (ja) * 1991-02-19 1993-07-20 Nippon Saafuakutanto Kogyo Kk 難溶解性薬物溶解剤組成物
JPH058169A (ja) 1991-07-02 1993-01-19 Daido Steel Co Ltd 湿式磁気研磨方法および研磨材
WO1994025575A1 (en) * 1993-04-30 1994-11-10 Novo Nordisk A/S An enzyme exhibiting pectin methylesterase activity
JP3661706B2 (ja) * 1993-10-28 2005-06-22 三省製薬株式会社 皮膚外用剤
US5891846A (en) * 1994-02-17 1999-04-06 Shiseido Company, Ltd. Cyclosporin-containing emulsion composition
US5830827A (en) * 1995-09-21 1998-11-03 Ishihara Sangyo Kaisha, Ltd. Granular herbicidal composition comprising flazasulfuron and a sulfosuccinate or benzoate stabilizer
JPH09151108A (ja) * 1995-11-30 1997-06-10 Kose Corp 油中水型乳化化粧料
JP3537622B2 (ja) 1996-02-26 2004-06-14 株式会社資生堂 紫外線吸収性組成物
JP2000136122A (ja) 1998-10-28 2000-05-16 Kose Corp 皮膚外用剤
FR2804024B1 (fr) * 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
BRPI0109198B8 (pt) * 2000-03-17 2021-05-25 Hisamitsu Pharmaceutical Co emplastro tendo um apoio
DE60112237D1 (de) 2001-02-22 2005-09-01 Menarini France S A Entzündungshemmende Arzneizubereitungen enthaltend Ketoprofen
JP4048418B2 (ja) * 2002-04-24 2008-02-20 東洋紡績株式会社 延伸ポリエステルフィルム及び、その製造方法
US20040220259A1 (en) * 2003-04-04 2004-11-04 Yu Ruey J. Topical treatment of dermatological disorders associated with reactive or dilated blood vessels
US6927206B2 (en) * 2003-06-06 2005-08-09 Procyte Corporation Compositions and methods for treatment of rosacea
TWI337086B (en) * 2003-09-03 2011-02-11 Hisamitsu Pharmaceutical Co Transdermal formulation containing nonsteroidal antiinflammatory drug

Also Published As

Publication number Publication date
EP1767218A1 (en) 2007-03-28
JP4990617B2 (ja) 2012-08-01
US7928144B2 (en) 2011-04-19
JPWO2005123136A1 (ja) 2008-04-10
ES2590258T3 (es) 2016-11-21
US20080031835A1 (en) 2008-02-07
EP1767218A4 (en) 2010-11-03
US20110028555A1 (en) 2011-02-03
US8877813B2 (en) 2014-11-04
TW200602031A (en) 2006-01-16
WO2005123136A1 (ja) 2005-12-29
EP1767218B1 (en) 2016-08-10

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