TWI322689B - Method for treating severe heart failure and medicament therefor - Google Patents

Method for treating severe heart failure and medicament therefor Download PDF

Info

Publication number
TWI322689B
TWI322689B TW093102582A TW93102582A TWI322689B TW I322689 B TWI322689 B TW I322689B TW 093102582 A TW093102582 A TW 093102582A TW 93102582 A TW93102582 A TW 93102582A TW I322689 B TWI322689 B TW I322689B
Authority
TW
Taiwan
Prior art keywords
active ingredient
heart failure
pharmaceutically acceptable
acceptable salt
contained
Prior art date
Application number
TW093102582A
Other languages
English (en)
Chinese (zh)
Other versions
TW200418489A (en
Inventor
Atsushi Ozaki
Yosuke Maki
Osamu Sato
Yoshitaka Yamamura
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32908667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI322689(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of TW200418489A publication Critical patent/TW200418489A/zh
Application granted granted Critical
Publication of TWI322689B publication Critical patent/TWI322689B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW093102582A 2003-02-24 2004-02-05 Method for treating severe heart failure and medicament therefor TWI322689B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44887803P 2003-02-24 2003-02-24

Publications (2)

Publication Number Publication Date
TW200418489A TW200418489A (en) 2004-10-01
TWI322689B true TWI322689B (en) 2010-04-01

Family

ID=32908667

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093102582A TWI322689B (en) 2003-02-24 2004-02-05 Method for treating severe heart failure and medicament therefor

Country Status (23)

Country Link
US (2) US7423032B2 (enExample)
EP (2) EP2000142A1 (enExample)
JP (2) JP4771937B2 (enExample)
KR (1) KR100706727B1 (enExample)
CN (1) CN100577171C (enExample)
AR (1) AR043259A1 (enExample)
AT (1) ATE411803T1 (enExample)
AU (2) AU2004212842B9 (enExample)
BR (1) BRPI0405657A (enExample)
CA (1) CA2493475A1 (enExample)
CY (1) CY1108583T1 (enExample)
DE (1) DE602004017283D1 (enExample)
DK (1) DK1596868T3 (enExample)
ES (1) ES2315640T3 (enExample)
MX (1) MXPA05001623A (enExample)
MY (1) MY143740A (enExample)
NO (1) NO335369B1 (enExample)
PL (2) PL218069B1 (enExample)
PT (1) PT1596868E (enExample)
RU (2) RU2346689C2 (enExample)
SI (1) SI1596868T1 (enExample)
TW (1) TWI322689B (enExample)
WO (1) WO2004073716A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468390B2 (en) * 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
TWI322689B (en) * 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CA2633929A1 (en) 2005-12-27 2007-07-05 Otsuka Pharmaceutical Co., Ltd. Water-soluble benzoazepine compound and its pharmaceutical composition
JP5076327B2 (ja) * 2006-02-01 2012-11-21 味の素株式会社 分岐鎖アミノ酸の心不全適応
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
HRP20130920T1 (hr) * 2007-05-15 2013-11-08 Otsuka Pharmaceutical Co., Ltd. Postupak uporabe antagonista vazopresina s kemoterapijom antraciklina radi snižavanja kardiotoksiäśnosti i/ili poboljšanja stope preživljavanja
TWI405574B (zh) * 2007-06-21 2013-08-21 Otsuka Pharma Co Ltd 藥學固體製劑及其製造方法
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
ES2903231T3 (es) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
WO2011147849A1 (en) 2010-05-25 2011-12-01 Jenavalve Technology Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
JP5477413B2 (ja) * 2012-04-24 2014-04-23 味の素株式会社 分岐鎖アミノ酸の心不全適応
JP6563394B2 (ja) 2013-08-30 2019-08-21 イェーナヴァルヴ テクノロジー インコーポレイテッド 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法
JP6829692B2 (ja) 2015-03-20 2021-02-10 イェーナヴァルヴ テクノロジー インコーポレイテッド 心臓弁プロテーゼ送出システム及び導入体シースにより心臓弁プロテーゼを送出するための方法
EP4403138A3 (en) 2015-05-01 2024-10-09 JenaValve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
CN109475419B (zh) 2016-05-13 2021-11-09 耶拿阀门科技股份有限公司 用于通过引导鞘和装载系统来递送心脏瓣膜假体的心脏瓣膜假体递送系统和方法
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry
CN110174474B (zh) * 2019-05-24 2022-02-18 石家庄四药有限公司 复方电解质注射液(ⅱ)中l-苹果酸异构体的检测方法
CN112121051B (zh) * 2020-09-30 2021-06-18 郑州大学 莫扎伐坦在制备抗消化道肿瘤药物中的应用
JP2025538294A (ja) 2022-11-09 2025-11-27 イエナバルブ テクノロジー インク 拡張可能なインプラントの順次展開のためのカテーテルシステム

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01102124A (ja) 1987-10-14 1989-04-19 Kubota Ltd コンクリート構造体支持構造
WO1991005549A1 (en) 1989-10-20 1991-05-02 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
US5753677A (en) * 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
US5258510A (en) 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
EP0602209A1 (en) 1992-07-02 1994-06-22 Otsuka Pharmaceutical Co., Ltd. Oxytocin antagonist
JPH0680641A (ja) 1992-09-01 1994-03-22 Otsuka Pharmaceut Co Ltd 光学活性な5−ヒドロキシベンゾアゼピン誘導体の製造法
TW354762B (en) 1993-02-23 1999-03-21 Otsuka Pharma Co Ltd Agent for prophylaxis or treatment of cataract
JP2694319B2 (ja) 1993-12-24 1997-12-24 大塚製薬株式会社 抗潰瘍剤
JP3002766B2 (ja) 1994-12-09 2000-01-24 大塚製薬株式会社 脳浮腫治療剤
JPH10120592A (ja) 1996-10-22 1998-05-12 Otsuka Pharmaceut Co Ltd メニエール病乃至メニエール症候群治療剤
JP4210355B2 (ja) 1997-07-03 2009-01-14 大塚製薬株式会社 固形製剤組成物
BR0017074A (pt) 2000-01-26 2002-12-03 Warner Lambert Co Combinações de inibidor de ace-antagonista de vasopressina
US20030103983A1 (en) * 2002-05-09 2003-06-05 Pressler Milton Lethan Ace inhibitor-vasopressin antagonist combinations
US20030008860A1 (en) 2002-05-09 2003-01-09 Bakker-Arkema Rebecca Guggemos Treatment of congestive heart failure
CA2357833C (en) * 2000-10-04 2005-11-15 Warner-Lambert Company Treatment of pulmonary hypertension using vasopressin antagonist
TWI322689B (en) * 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor

Also Published As

Publication number Publication date
AU2004212842A1 (en) 2004-09-02
PL373432A1 (en) 2005-08-22
NO20050569L (no) 2005-11-22
RU2346689C2 (ru) 2009-02-20
MY143740A (en) 2011-07-15
CA2493475A1 (en) 2004-09-02
PL218069B1 (pl) 2014-10-31
CN100577171C (zh) 2010-01-06
US20080214523A1 (en) 2008-09-04
DE602004017283D1 (de) 2008-12-04
HK1084037A1 (zh) 2006-07-21
EP1596868A4 (en) 2006-03-29
MXPA05001623A (es) 2005-04-25
EP1596868A1 (en) 2005-11-23
AU2004212842B2 (en) 2009-01-08
PT1596868E (pt) 2009-01-14
JP2006518731A (ja) 2006-08-17
US7423032B2 (en) 2008-09-09
CN1700919A (zh) 2005-11-23
WO2004073716A1 (en) 2004-09-02
KR100706727B1 (ko) 2007-04-12
KR20050105972A (ko) 2005-11-08
RU2008133654A (ru) 2010-02-20
SI1596868T1 (sl) 2008-12-31
PL404315A1 (pl) 2013-08-05
ES2315640T3 (es) 2009-04-01
JP4771937B2 (ja) 2011-09-14
NO20050569D0 (no) 2005-02-02
CY1108583T1 (el) 2014-04-09
BRPI0405657A (pt) 2005-07-19
NO335369B1 (no) 2014-12-01
US20050187210A1 (en) 2005-08-25
EP1596868B1 (en) 2008-10-22
AU2009201109A1 (en) 2009-04-09
RU2005102110A (ru) 2005-09-20
TW200418489A (en) 2004-10-01
AU2004212842B9 (en) 2009-03-05
ATE411803T1 (de) 2008-11-15
AR043259A1 (es) 2005-07-20
DK1596868T3 (da) 2008-12-08
EP2000142A1 (en) 2008-12-10
JP2011148806A (ja) 2011-08-04
US7749993B2 (en) 2010-07-06

Similar Documents

Publication Publication Date Title
TWI322689B (en) Method for treating severe heart failure and medicament therefor
EP3908276B1 (en) Methods of treating conditions related to the s1p1 receptor
JPH05186332A (ja) 少なくとも2種の異なる作用物質を備えた薬剤学的製剤の製造方法と使用
JP2025013684A (ja) 重度腎機能障害を有する癌患者に対する治療方法
JP2007169278A (ja) Luts処置用の医薬組合せ
CN116887826A (zh) 治疗与s1p1受体相关的病症的方法
CN115515599A (zh) 化合物在真菌感染的治疗中的用途
KR102512518B1 (ko) 페마피브레이트를 함유하는 의약
EP4360631A1 (en) Pharmaceutical composition comprising 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazole-4-carboxylic acid
US12336978B2 (en) Pharmaceutical composition containing amlodipine, chlorthalidone, and amiloride and application thereof
EP4616867A1 (en) Combination of endothelin receptor antagonist and glucocorticoid for treating iga nephropathy
JP3758700B2 (ja) 徐脈性不整脈治療剤
WO2006105726A1 (en) A composition for treating hypertension
HK1084037B (en) Medicament for treating severe heart failure
CN117794544A (zh) 实体瘤治疗用医药组合物
HK40087811A (zh) 用於治疗具有严重肝损伤的受试者的非转移性去势抵抗性前列腺癌的雄激素受体抑制剂
CN117157073A (zh) 用墨蝶呤治疗胶质母细胞瘤的方法
CN115666564A (zh) 在单层片剂中包括氨氯地平、氯沙坦和氯噻酮的预防或治疗心血管系统疾病的药学上组合制剂
JP2006036712A (ja) 脳梗塞予防または治療薬としてのビトロネクチン拮抗物質
CN109069438A (zh) 包含β阻滞剂、转化酶抑制剂和抗高血压药或NSAID的药物组合物

Legal Events

Date Code Title Description
MK4A Expiration of patent term of an invention patent