TWI311152B - Host-vector system for antibiotic-free cole1 plasmid propagation - Google Patents

Host-vector system for antibiotic-free cole1 plasmid propagation Download PDF

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Publication number
TWI311152B
TWI311152B TW94130459A TW94130459A TWI311152B TW I311152 B TWI311152 B TW I311152B TW 94130459 A TW94130459 A TW 94130459A TW 94130459 A TW94130459 A TW 94130459A TW I311152 B TWI311152 B TW I311152B
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TW
Taiwan
Prior art keywords
plastid
sequence
rna
protein
gene
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TW94130459A
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English (en)
Chinese (zh)
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TW200621985A (en
Inventor
Reingard Grabherr
Irene Pfaffenzeller
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Boehringer Ingelheim Rcv Gmbh & Co K
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Application filed by Boehringer Ingelheim Rcv Gmbh & Co K filed Critical Boehringer Ingelheim Rcv Gmbh & Co K
Publication of TW200621985A publication Critical patent/TW200621985A/zh
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Publication of TWI311152B publication Critical patent/TWI311152B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW94130459A 2004-09-17 2005-09-06 Host-vector system for antibiotic-free cole1 plasmid propagation TWI311152B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04022201 2004-09-17

Publications (2)

Publication Number Publication Date
TW200621985A TW200621985A (en) 2006-07-01
TWI311152B true TWI311152B (en) 2009-06-21

Family

ID=34926585

Family Applications (1)

Application Number Title Priority Date Filing Date
TW94130459A TWI311152B (en) 2004-09-17 2005-09-06 Host-vector system for antibiotic-free cole1 plasmid propagation

Country Status (13)

Country Link
US (2) US20060063232A1 (enExample)
EP (1) EP1794299B1 (enExample)
JP (1) JP5301832B2 (enExample)
KR (2) KR101023066B1 (enExample)
CN (2) CN103555644B (enExample)
AR (2) AR050649A1 (enExample)
AU (1) AU2005284136B2 (enExample)
BR (1) BRPI0515436A (enExample)
CA (1) CA2580009C (enExample)
IL (1) IL181919A (enExample)
NZ (1) NZ554236A (enExample)
TW (1) TWI311152B (enExample)
WO (1) WO2006029985A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0327056D0 (en) * 2003-11-20 2003-12-24 Cobra Biolog Ltd Plasmid maintenance
AU2008252990B2 (en) 2007-05-17 2015-01-15 Boehringer Ingelheim Rcv Gmbh & Co Kg Method for producing a recombinant protein on a manufacturing scale
EP2152889B1 (en) * 2007-05-29 2017-03-15 Nature Technology Corporation Vectors and methods for genetic immunization
EP2173879A4 (en) * 2007-07-16 2010-10-20 Royal Veterinary College GEN / INHIBITOR COMBINATIONS WITH MUTUAL SUPPRESSION FOR THE ANTIBIOTIC-FREE SELECTION OF RECOMBINANT STRAINS
JP5538691B2 (ja) * 2007-11-22 2014-07-02 独立行政法人科学技術振興機構 Ｒｎａ−蛋白質相互作用モチーフを利用した蛋白質応答翻訳制御システム
EP2500427B1 (en) 2007-11-22 2014-07-30 Japan Science and Technology Agency Translation regulation system in cell or artifical cell model by using low-molecular-weight RNA
HUE031597T2 (en) * 2009-05-22 2017-07-28 Merial Inc Antibiotic-free plasmid
US20110269184A1 (en) 2009-07-16 2011-11-03 Boehringer Ingelheim Rcv Gmbh & Co. Kg Method for controlling plasmid copy number in e.coli
WO2012082946A2 (en) * 2010-12-14 2012-06-21 The Regents Of The University Of California Creation of super-stable coie1 plasmids by duplication of sl 1-4 sequence and point mutations.
GB201021795D0 (en) * 2010-12-21 2011-02-02 Msd Biolog Uk Ltd Expression Process
EP2890404B1 (en) 2012-08-29 2018-06-13 Nature Technology Corporation Dna plasmids with improved expression
WO2014077863A1 (en) 2012-11-19 2014-05-22 Nature Technology Corporation Replicative minicircle vectors with improved expression
JP7161991B2 (ja) * 2016-11-02 2022-10-27 アーチャーディーエックス， エルエルシー 免疫レパートリーシーケンシングのための核酸サンプル調製の方法
CN107142272A (zh) * 2017-06-05 2017-09-08 南京金斯瑞生物科技有限公司 一种控制大肠杆菌中质粒复制的方法
DK3456821T4 (da) 2017-09-19 2024-04-15 Deutsches Krebsforsch Ikke-integrerende dna-vektorer til genetisk modifikation af celler
WO2019057774A1 (en) 2017-09-19 2019-03-28 Deutsches Krebsforschungszentrum NON-INTEGRATING DNA VECTORS FOR THE GENETIC MODIFICATION OF CELLS
JP7520719B2 (ja) 2018-03-21 2024-07-23 アルデブロン，エル．エル．シー． 生成が改良されたウイルス及び非ウイルスのナノプラスミドベクター
JP7661015B2 (ja) 2020-06-12 2025-04-14 ナガセヴィータ株式会社 目的タンパク質の製造方法
WO2023166132A1 (en) * 2022-03-04 2023-09-07 Gen-H Genetic Engineering Heidelberg Gmbh Microorganism strain for antibiotic-free plasmid-based fermentation and method for generation thereof
CN117187281A (zh) * 2023-09-11 2023-12-08 云舟生物科技(广州)股份有限公司 一种无抗性质粒生产系统及其应用
CN118028194B (zh) * 2023-12-26 2024-09-06 浙江大学 基因组精简的恶臭假单胞菌菌株
WO2025160245A1 (en) 2024-01-25 2025-07-31 Aldevron, L.L.C. Viral and non-viral nanoplasmid vectors with improved production
WO2025231315A2 (en) 2024-05-03 2025-11-06 Aldevron, L.L.C. Bacterial host strains

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215541D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
US5922583A (en) * 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
EP1195436A1 (en) 2000-10-04 2002-04-10 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Expression vectors with modified ColE1 origin of replication for control of plasmid copy number
US20040248083A1 (en) * 2001-05-17 2004-12-09 Mikkelsen Jacob Giehm Vectors for gene therapy
SE0102204D0 (sv) * 2001-06-21 2001-06-21 Leif Isaksson New method
CN1490056A (zh) * 2002-10-18 2004-04-21 ��¡���ɵ°��̲��о����� 针对hiv-1的免疫方法和组合物
GB0327056D0 (en) 2003-11-20 2003-12-24 Cobra Biolog Ltd Plasmid maintenance

Also Published As

Publication number Publication date
IL181919A (en) 2012-04-30
CA2580009C (en) 2013-12-17
AR050649A1 (es) 2006-11-08
AU2005284136B2 (en) 2011-07-14
TW200621985A (en) 2006-07-01
KR101023066B1 (ko) 2011-03-24
AU2005284136A1 (en) 2006-03-23
CN103555644A (zh) 2014-02-05
US20090263861A1 (en) 2009-10-22
KR20100101689A (ko) 2010-09-17
EP1794299A2 (en) 2007-06-13
KR20070059130A (ko) 2007-06-11
NZ554236A (en) 2010-05-28
WO2006029985A3 (en) 2006-07-27
EP1794299B1 (en) 2015-09-02
CN101052722A (zh) 2007-10-10
US9297014B2 (en) 2016-03-29
BRPI0515436A (pt) 2008-07-22
AR079958A2 (es) 2012-02-29
JP2008512998A (ja) 2008-05-01
US20060063232A1 (en) 2006-03-23
IL181919A0 (en) 2007-07-04
CN103555644B (zh) 2018-06-01
JP5301832B2 (ja) 2013-09-25
WO2006029985A2 (en) 2006-03-23
CA2580009A1 (en) 2006-03-23

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