TWI245739B - Method and device for flowing a liquid on a surface - Google Patents
Method and device for flowing a liquid on a surface Download PDFInfo
- Publication number
- TWI245739B TWI245739B TW92130479A TW92130479A TWI245739B TW I245739 B TWI245739 B TW I245739B TW 92130479 A TW92130479 A TW 92130479A TW 92130479 A TW92130479 A TW 92130479A TW I245739 B TWI245739 B TW I245739B
- Authority
- TW
- Taiwan
- Prior art keywords
- port
- liquid
- flow path
- pressure
- flow
- Prior art date
Links
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0262—Drop counters; Drop formers using touch-off at substrate or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
- B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
- B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
- B01J8/20—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles with liquid as a fluidising medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C5/00—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
- B05C5/02—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
- B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/0038—Drawing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00427—Means for dispensing and evacuation of reagents using masks
- B01J2219/0043—Means for dispensing and evacuation of reagents using masks for direct application of reagents, e.g. through openings in a shutter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/089—Virtual walls for guiding liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/022—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/9682—Miscellaneous
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Combustion & Propulsion (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Micromachines (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02027180 | 2002-12-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200415115A TW200415115A (en) | 2004-08-16 |
| TWI245739B true TWI245739B (en) | 2005-12-21 |
Family
ID=32405694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW92130479A TWI245739B (en) | 2002-12-05 | 2003-10-31 | Method and device for flowing a liquid on a surface |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7329111B2 (OSRAM) |
| EP (1) | EP1567265B1 (OSRAM) |
| JP (1) | JP4808406B2 (OSRAM) |
| KR (1) | KR100702504B1 (OSRAM) |
| CN (1) | CN100562362C (OSRAM) |
| AU (1) | AU2003283627A1 (OSRAM) |
| TW (1) | TWI245739B (OSRAM) |
| WO (1) | WO2004050246A1 (OSRAM) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050247673A1 (en) * | 2004-05-07 | 2005-11-10 | International Business Machines Corporation | Confinement of fluids on surfaces |
| DE102005017653A1 (de) | 2005-04-15 | 2006-10-19 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und Verfahren zur Manipulation einer Flüssigkeit |
| CN101548168B (zh) * | 2007-07-20 | 2012-06-27 | 爱科来株式会社 | 检体供给器具及使用该器具的检体分析用具 |
| EP2506976A2 (en) | 2009-12-03 | 2012-10-10 | Owe Owar | Pipettes, methods of use, and methods of stimulating an object of interest |
| ITMI20100407A1 (it) * | 2010-03-12 | 2011-09-13 | Rise Technology S R L | Cella foto-voltaica con regioni di semiconduttore poroso per ancorare terminali di contatto |
| FI3885045T3 (fi) * | 2011-05-06 | 2026-03-19 | Fluicell Ab | Mikrofluidilaite pitoliitännällä ja käyttömenetelmä |
| US10436683B2 (en) | 2012-02-27 | 2019-10-08 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sample processing device with detachable slide |
| WO2013183013A1 (en) | 2012-06-06 | 2013-12-12 | De Oliva Novo Pedro Jose | Autonomous and programmable sequential flow of solutions in capillary microfluidics |
| US9021864B2 (en) | 2012-08-21 | 2015-05-05 | International Business Machines Corporation | Sensing biomolecules using scanning probe with twin-nanopore to detect a change in the magnitude of the current through the second nanopore |
| DE102013205889B3 (de) | 2013-04-03 | 2014-05-28 | Kennametal Inc. | Kupplungsteil, insbesondere Schneidkopf für ein Rotationswerkzeug sowie ein derartiges Rotationswerkzeug |
| DE102013220884B4 (de) | 2013-10-15 | 2022-02-17 | Kennametal Inc. | Modulares Trägerwerkzeug sowie Werkzeugkopf |
| CN103808776B (zh) * | 2014-03-12 | 2017-11-14 | 杭州霆科生物科技有限公司 | 电化学传感器的制备方法 |
| DE102014206796B4 (de) | 2014-04-08 | 2020-10-15 | Kennametal Inc. | Rotationswerkzeug, insbesondere Bohrer sowie Schneidkopf für ein solches Rotationswerkzeug |
| WO2016113691A1 (en) | 2015-01-14 | 2016-07-21 | Bio-Rad Laboratories, Inc. | Blood analysis systems and methods |
| US10330675B2 (en) | 2015-01-23 | 2019-06-25 | Bio-Rad Laboratories, Inc. | Immunoblotting systems and methods |
| DE102015211744B4 (de) | 2015-06-24 | 2023-07-20 | Kennametal Inc. | Rotationswerkzeug, insbesondere Bohrer, und Schneidkopf für ein solches Rotationswerkzeug |
| USD798922S1 (en) | 2015-10-07 | 2017-10-03 | Kennametal Inc. | Cutting head for rotary drill |
| US10071430B2 (en) | 2015-10-07 | 2018-09-11 | Kennametal Inc. | Cutting head, rotary tool and support for the rotary tool and for the accommodation of the cutting head |
| USD798921S1 (en) | 2015-10-07 | 2017-10-03 | Kennametal Inc. | Cutting head for modular drill |
| US9937567B2 (en) | 2015-10-07 | 2018-04-10 | Kennametal Inc. | Modular drill |
| DE102017205166B4 (de) | 2017-03-27 | 2021-12-09 | Kennametal Inc. | Modulares Rotationswerkzeug und modulares Werkzeugsystem |
| DE102017212054B4 (de) | 2017-07-13 | 2019-02-21 | Kennametal Inc. | Verfahren zur Herstellung eines Schneidkopfes sowie Schneidkopf |
| US10799958B2 (en) | 2017-08-21 | 2020-10-13 | Kennametal Inc. | Modular rotary cutting tool |
| EP3861356A4 (en) | 2018-10-01 | 2022-07-06 | Polyvalor, Limited Partnership | System and method of fluid delivery |
| US11298769B2 (en) | 2019-05-13 | 2022-04-12 | International Business Machines Corporation | Prevention of dripping of material for material injection |
| CN112077370B (zh) | 2019-06-13 | 2024-10-01 | 肯纳金属印度有限公司 | 可转位钻头刀片 |
| EP3766577A1 (en) * | 2019-07-16 | 2021-01-20 | Imec VZW | Passive fluidic connection between two hydrophilic substrates |
| CN115703157A (zh) | 2021-08-17 | 2023-02-17 | 肯纳金属印度有限公司 | 具有冷却剂系统的可转位钻头组件 |
| JP2023042882A (ja) * | 2021-09-15 | 2023-03-28 | 株式会社Ｓｃｒｅｅｎホールディングス | 流路デバイス |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3526694A (en) * | 1968-02-06 | 1970-09-01 | Jerome H Lemelson | Molding techniques |
| EP0075605B1 (de) | 1981-09-25 | 1987-01-21 | Winfried Dr. med. Stöcker | Vorrichtung für photometrische Analysen |
| US5429807A (en) * | 1993-10-28 | 1995-07-04 | Beckman Instruments, Inc. | Method and apparatus for creating biopolymer arrays on a solid support surface |
| US6231333B1 (en) * | 1995-08-24 | 2001-05-15 | International Business Machines Corporation | Apparatus and method for vacuum injection molding |
| US6089853A (en) * | 1997-12-24 | 2000-07-18 | International Business Machines Corporation | Patterning device for patterning a substrate with patterning cavities fed by service cavities |
| US6251343B1 (en) * | 1998-02-24 | 2001-06-26 | Caliper Technologies Corp. | Microfluidic devices and systems incorporating cover layers |
| DE19827754C1 (de) * | 1998-06-23 | 2000-02-10 | Graffinity Pharm Design Gmbh | Einrichtung für eine nahezu gleichzeitige Synthese einer Vielzahl von Proben |
| WO1999056878A1 (de) | 1998-04-30 | 1999-11-11 | Graffinity Pharmaceutical Design Gmbh | Vorrichtung für den transport von flüssigkeiten entlang vorgegebener leitwege |
| DE19823660C1 (de) * | 1998-05-20 | 1999-10-07 | Nanomont Ges Fuer Nanotechnolo | Verfahren und Vorrichtung zur Fixierung fester Mikro- und/oder Nanoobjekte |
| DE19941871A1 (de) * | 1999-09-02 | 2001-04-19 | Hahn Schickard Ges | Vorrichtung und Verfahren zum Aufbringen einer Mehrzahl von Mikrotröpfchen auf ein Substrat |
| JP3865107B2 (ja) * | 2000-05-26 | 2007-01-10 | 横河電機株式会社 | バイオチップ作製方法およびそれを用いたバイオチップ作製装置 |
| US6953551B2 (en) * | 2000-02-22 | 2005-10-11 | Genospectra, Inc. | Microarray fabrication techniques and apparatus |
| US6720157B2 (en) | 2000-02-23 | 2004-04-13 | Zyomyx, Inc. | Chips having elevated sample surfaces |
| AU2001251340A1 (en) * | 2000-04-06 | 2001-10-23 | Caliper Technologies Corp. | Microfluidic devices and systems incorporating cover layers |
| JP2002075947A (ja) * | 2000-08-30 | 2002-03-15 | Alps Electric Co Ltd | ウェット処理装置 |
| AU2002248149A1 (en) * | 2000-11-16 | 2002-08-12 | Fluidigm Corporation | Microfluidic devices for introducing and dispensing fluids from microfluidic systems |
| CA2430651C (en) * | 2001-02-09 | 2010-10-12 | Wisconsin Alumni Research Foundation | Method and structure for microfluidic flow guiding |
| KR100916074B1 (ko) * | 2001-03-09 | 2009-09-08 | 바이오마이크로 시스템즈, 인크. | 어레이에 대한 마이크로유체 인터페이스 방법 및인터페이스용 시스템 |
| US6942836B2 (en) * | 2001-10-16 | 2005-09-13 | Applera Corporation | System for filling substrate chambers with liquid |
-
2003
- 2003-10-31 TW TW92130479A patent/TWI245739B/zh not_active IP Right Cessation
- 2003-11-13 US US10/537,238 patent/US7329111B2/en not_active Expired - Lifetime
- 2003-11-13 AU AU2003283627A patent/AU2003283627A1/en not_active Abandoned
- 2003-11-13 JP JP2004556622A patent/JP4808406B2/ja not_active Expired - Fee Related
- 2003-11-13 KR KR1020057008084A patent/KR100702504B1/ko not_active Expired - Fee Related
- 2003-11-13 CN CNB2003801051797A patent/CN100562362C/zh not_active Expired - Fee Related
- 2003-11-13 WO PCT/IB2003/005350 patent/WO2004050246A1/en not_active Ceased
- 2003-11-13 EP EP20030775606 patent/EP1567265B1/en not_active Expired - Lifetime
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2007
- 2007-08-09 US US11/836,259 patent/US7740472B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1567265B1 (en) | 2014-07-02 |
| KR100702504B1 (ko) | 2007-04-03 |
| CN1720101A (zh) | 2006-01-11 |
| JP2006508789A (ja) | 2006-03-16 |
| KR20050084968A (ko) | 2005-08-29 |
| WO2004050246A1 (en) | 2004-06-17 |
| US7329111B2 (en) | 2008-02-12 |
| AU2003283627A1 (en) | 2004-06-23 |
| US20060093697A1 (en) | 2006-05-04 |
| US20080000536A1 (en) | 2008-01-03 |
| CN100562362C (zh) | 2009-11-25 |
| TW200415115A (en) | 2004-08-16 |
| JP4808406B2 (ja) | 2011-11-02 |
| EP1567265A1 (en) | 2005-08-31 |
| US7740472B2 (en) | 2010-06-22 |
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