TWI242544B - Process for coupling organic compounds - Google Patents

Process for coupling organic compounds Download PDF

Info

Publication number
TWI242544B
TWI242544B TW90115188A TW90115188A TWI242544B TW I242544 B TWI242544 B TW I242544B TW 90115188 A TW90115188 A TW 90115188A TW 90115188 A TW90115188 A TW 90115188A TW I242544 B TWI242544 B TW I242544B
Authority
TW
Taiwan
Prior art keywords
scope
patent application
item
compound containing
microreactor
Prior art date
Application number
TW90115188A
Other languages
English (en)
Chinese (zh)
Inventor
Hanns Wurziger
Guido Pieper
Norbert Schwesinger
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of TWI242544B publication Critical patent/TWI242544B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/04—Substitution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2/00—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms
    • C07C2/86—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by condensation between a hydrocarbon and a non-hydrocarbon
    • C07C2/861—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by condensation between a hydrocarbon and a non-hydrocarbon the non-hydrocarbon contains only halogen as hetero-atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00835—Comprising catalytically active material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/00862—Dimensions of the reaction cavity itself
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00916—Separation by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2527/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • C07C2527/06—Halogens; Compounds thereof
    • C07C2527/122—Compounds comprising a halogen and copper
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2527/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • C07C2527/06—Halogens; Compounds thereof
    • C07C2527/128—Compounds comprising a halogen and an iron group metal or a platinum group metal
    • C07C2527/13—Platinum group metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • C07C2531/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • C07C2531/04—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing carboxylic acids or their salts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • C07C2531/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • C07C2531/22—Organic complexes
TW90115188A 2000-06-28 2001-06-22 Process for coupling organic compounds TWI242544B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2000131381 DE10031381A1 (de) 2000-06-28 2000-06-28 Verfahren zur Kupplung von organischen Verbindungen

Publications (1)

Publication Number Publication Date
TWI242544B true TWI242544B (en) 2005-11-01

Family

ID=7647033

Family Applications (1)

Application Number Title Priority Date Filing Date
TW90115188A TWI242544B (en) 2000-06-28 2001-06-22 Process for coupling organic compounds

Country Status (6)

Country Link
EP (1) EP1294660A2 (de)
JP (1) JP2004505895A (de)
AU (1) AU2001283818A1 (de)
DE (1) DE10031381A1 (de)
TW (1) TWI242544B (de)
WO (1) WO2002000577A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1534421B1 (de) 2002-08-15 2006-09-27 Velocys, Inc. Verfahren in mikrokanalreaktoren mit gebundenem katalysator und einen gebundenen katalysator oder gebundene chirale hilfsmittel enthaltende systeme
AT501927B1 (de) * 2005-05-23 2007-06-15 Dsm Fine Chem Austria Gmbh Verbessertes verfahren zur durchführung von ritterreaktionen, elektrophilen additionen an alkenen oder friedel-crafts-alkylierungen
JP2008081450A (ja) * 2006-09-28 2008-04-10 Dainippon Ink & Chem Inc フェノール類二量体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE170773T1 (de) * 1994-05-09 1998-09-15 Bayer Ag Verfahren und vorrichtung zur durchführung chemischer reaktionen mittels mikrostruktur- mischung
GB9723260D0 (en) * 1997-11-05 1998-01-07 British Nuclear Fuels Plc A method of performing a chemical reaction
GB9723262D0 (en) * 1997-11-05 1998-01-07 British Nuclear Fuels Plc Reactions of aromatic compounds

Also Published As

Publication number Publication date
AU2001283818A1 (en) 2002-01-08
WO2002000577A3 (de) 2002-05-02
WO2002000577A2 (de) 2002-01-03
DE10031381A1 (de) 2002-01-10
JP2004505895A (ja) 2004-02-26
EP1294660A2 (de) 2003-03-26

Similar Documents

Publication Publication Date Title
Keske et al. Synthesis and structure of silver and rhodium 1, 2, 3-triazol-5-ylidene mesoionic carbene complexes
Helmecke et al. Metal-free activation of C–I bonds and perfluoroalkylation of alkenes with visible light using phosphine catalysts
Totobenazara et al. New click-chemistry methods for 1, 2, 3-triazoles synthesis: Recent advances and applications
Manarin et al. Electrophilic cyclization of 2-chalcogenealkynylanisoles: Versatile access to 2-chalcogen-benzo [b] furans
Carreras et al. Polycationic ligands in gold catalysis: synthesis and applications of extremely π-acidic catalysts
TW483883B (en) Coupling reactions for the preparation of biphenyls or aromatic olefins with allyl palladium catalysts
Date et al. Catalytic direct cyclization of alkenyl thioester
Clarke First Microwave‐Accelerated Hiyama Coupling of Aryl‐and Vinylsiloxane Derivatives: Clean Cross‐Coupling of Aryl Chlorides within Minutes
Mitsui et al. Synthesis of adamantyl substituted 1, 2, 3-triazol-5-ylidene ligands and their PEPPSI-type palladium complexes
JP7010822B2 (ja) キラルなホスホルアミドイミデートおよびその誘導体
JP2008526925A (ja) 圧縮二酸化炭素中で連続的閉環メタセシスを行う方法
van Koten Organocopper Compounds: From Elusive to Isolable Species, from Early Supramolecular Chemistry with RCuI Building Blocks to Mononuclear R2–n CuII and R3–m CuIII Compounds. A Personal View
Borst et al. 3 H-Benzophosphepine complexes: versatile phosphinidene precursors
Shieh et al. Syntheses of thioethers and selenide ethers from anilines
US6852900B2 (en) Method for carrying out a metathesis reaction of unsaturated organic compounds
López-Saucedo et al. Palladium complexes bearing pyridylthioether ligands. Synthesis and application as efficient phosphine-free catalysts in Suzuki-Miyaura couplings
Liu et al. A planar π-conjugated naphthyridine-based N-heterocyclic carbene ligand and its derived transition-metal complexes
JP2004501879A (ja) アルキリデン基を有機化合物に転移させるための方法
Ahmed et al. A K-arylacetylide complex for catalytic terminal alkyne functionalization using KO t Bu as a precatalyst
Yu et al. Synthesis of Aryl Alkynes via Copper Catalyzed Decarboxylative Alkynylation of 2-Nitrobenzoic Acids
Medina-Mercado et al. Gold-catalyzed ascorbic acid-induced arylative carbocyclization of alkynes with aryldiazonium tetrafluoroborates
TWI242544B (en) Process for coupling organic compounds
Mali et al. Copper-mediated synthesis of (E)-1-Azido and (Z)-1, 2-Diazido alkenes from 1-alkene-1, 2-diboronic esters: an approach to mono-and 1, 2-di-(1, 2, 3-Triazolyl)-alkenes and fused bis-(1, 2, 3-Triazolo)-pyrazines
Shaik et al. Synthesis of a new class of cationic Pd (II) complexes with 1, 2, 3-triazol-5-ylidene ligand and their catalytic application in the conversion of internal alkynes to 1, 2-diketones
Mysliwiec et al. Stereoselective Wittig Olefination as a macrocyclization tool. synthesis of large carbazolophanes

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees