TW457247B - Novel antigen - Google Patents

Novel antigen Download PDF

Info

Publication number
TW457247B
TW457247B TW085111139A TW85111139A TW457247B TW 457247 B TW457247 B TW 457247B TW 085111139 A TW085111139 A TW 085111139A TW 85111139 A TW85111139 A TW 85111139A TW 457247 B TW457247 B TW 457247B
Authority
TW
Taiwan
Prior art keywords
protein
omp26
page
amino acid
ministry
Prior art date
Application number
TW085111139A
Other languages
English (en)
Chinese (zh)
Inventor
Jennelle Kyd
Allan Cripps
Christopher John Smith
Original Assignee
Cortecs Internat Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortecs Internat Ltd filed Critical Cortecs Internat Ltd
Application granted granted Critical
Publication of TW457247B publication Critical patent/TW457247B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
TW085111139A 1995-06-27 1996-09-12 Novel antigen TW457247B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9513074.6A GB9513074D0 (en) 1995-06-27 1995-06-27 Novel anigen

Publications (1)

Publication Number Publication Date
TW457247B true TW457247B (en) 2001-10-01

Family

ID=10776746

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085111139A TW457247B (en) 1995-06-27 1996-09-12 Novel antigen

Country Status (18)

Country Link
US (4) US6245338B1 (enExample)
EP (1) EP0835313B1 (enExample)
JP (2) JPH11510373A (enExample)
KR (1) KR19990028423A (enExample)
CN (1) CN1144875C (enExample)
AT (1) ATE317013T1 (enExample)
AU (1) AU708061B2 (enExample)
CA (1) CA2225405A1 (enExample)
DE (1) DE69635783T2 (enExample)
ES (1) ES2259443T3 (enExample)
GB (1) GB9513074D0 (enExample)
MX (1) MX9710412A (enExample)
NO (1) NO976119L (enExample)
NZ (1) NZ311120A (enExample)
RU (1) RU2221045C2 (enExample)
TW (1) TW457247B (enExample)
WO (1) WO1997001638A1 (enExample)
ZA (1) ZA965482B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355450B1 (en) 1995-04-21 2002-03-12 Human Genome Sciences, Inc. Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof
US6468765B1 (en) 1995-04-21 2002-10-22 Human Genome Sciences, Inc. Selected Haemophilus influenzae Rd polynucleotides and polypeptides
GB9904183D0 (en) * 1999-02-24 1999-04-14 Smithkline Beecham Biolog Novel compounds
EP1162999B1 (en) 1999-03-19 2006-11-29 Glaxosmithkline Biologicals S.A. Vaccine against Streptococcus pneumoniae
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
AU2002211999A1 (en) * 2000-10-02 2002-04-15 Id Biomedical Corporation Haemophilus influenzae antigens and corresponding DNA fragments
RU2185191C1 (ru) * 2001-02-01 2002-07-20 Ростовский научно-исследовательский институт микробиологии и паразитологии Способ получения антигенного препарата haemophilus influenzae типа b (hib)
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
DK2255826T3 (en) 2002-08-02 2016-06-20 Glaxosmithkline Biologicals Sa Neisserial vaccine compositions comprising a combination of antigens.
BRPI0609460A2 (pt) * 2005-03-30 2010-04-13 Novartis Vaccines & Diagnostics Inc haemophilus influenzae tipo b
CN100357318C (zh) * 2005-10-11 2007-12-26 中山大学 美人鱼发光杆菌外膜蛋白w和编码序列及其制备方法和应用
KR100743604B1 (ko) * 2005-12-05 2007-07-27 볼보 컨스트럭션 이키프먼트 홀딩 스웨덴 에이비 차량용 머플러 구조
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
PL3017827T3 (pl) 2005-12-22 2019-04-30 Glaxosmithkline Biologicals Sa Szczepionka z koniugatem polisacharydu pneumokokowego
NO346497B1 (no) 2006-01-17 2022-09-05 Arne Forsgren Overflateeksponert haemophilus influenzae protein (protein E, pE)
US9610339B2 (en) 2007-06-26 2017-04-04 Glaxosmithkline Biologicals, S.A. Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
JP2013521326A (ja) 2010-03-10 2013-06-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原性組成物
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
EP2717909B1 (en) 2011-06-04 2017-12-06 Rochester General Hospital Research Institute Compositions and methods related to p6 of haemophilus influenzae
RU2727476C2 (ru) * 2012-04-26 2020-07-21 Новартис Аг Антигены и антигенные композиции
CN104370997B (zh) * 2014-09-24 2018-07-31 陈辉 去除生物制品中细菌内毒素的试剂盒、方法及其生物制品的制备方法
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
FR3066920A1 (fr) 2017-05-30 2018-12-07 Glaxosmithkline Biologicals S.A. Nouveaux procedes de fabrication d'un adjuvant
WO2019106192A1 (en) 2017-12-01 2019-06-06 Glaxosmithkline Biologicals Sa Saponin purification
US20210283238A1 (en) 2018-08-07 2021-09-16 Glaxosmithkline Biologicals Sa Novel processes and vaccines
WO2020109365A1 (en) 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
CA3142300C (en) 2019-06-05 2025-02-04 Glaxosmithkline Biologicals Sa SAPONIN PURIFICATION
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2024017827A1 (en) 2022-07-19 2024-01-25 Glaxosmithkline Biologicals Sa Continuous process for vaccine production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462210B1 (en) * 1989-03-09 1994-09-07 Praxis Biologics, Inc. Vaccines for nontypable haemophilus influenzae
GB8924473D0 (en) * 1989-10-31 1989-12-20 Connaught Lab Outer membrane protein p1 and peptides of haemophilus influenzae b
GB9224584D0 (en) * 1992-11-23 1993-01-13 Connaught Lab Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases

Also Published As

Publication number Publication date
US6284477B1 (en) 2001-09-04
ZA965482B (en) 1997-12-29
WO1997001638A1 (en) 1997-01-16
DE69635783D1 (de) 2006-04-13
JPH11510373A (ja) 1999-09-14
US6254875B1 (en) 2001-07-03
JP2009034107A (ja) 2009-02-19
CN1144875C (zh) 2004-04-07
DE69635783T2 (de) 2006-11-02
CA2225405A1 (en) 1997-01-16
CN1189186A (zh) 1998-07-29
AU708061B2 (en) 1999-07-29
US6313281B1 (en) 2001-11-06
US6245338B1 (en) 2001-06-12
MX9710412A (es) 1998-07-31
NZ311120A (en) 1999-10-28
NO976119D0 (no) 1997-12-29
EP0835313A1 (en) 1998-04-15
EP0835313B1 (en) 2006-02-01
GB9513074D0 (en) 1995-08-30
KR19990028423A (ko) 1999-04-15
AU6236396A (en) 1997-01-30
NO976119L (no) 1998-02-26
ES2259443T3 (es) 2006-10-01
ATE317013T1 (de) 2006-02-15
RU2221045C2 (ru) 2004-01-10

Similar Documents

Publication Publication Date Title
TW457247B (en) Novel antigen
Ruffolo et al. Cloning, sequencing, expression, and protective capacity of the oma87 gene encoding the Pasteurella multocida 87-kilodalton outer membrane antigen
CN103893747B (zh) 增强针对艾美球虫属的免疫反应的组合物和方法
Kyd et al. Enhanced respiratory clearance of nontypeable Haemophilus influenzae following mucosal immunization with P6 in a rat model
JP4583607B2 (ja) 感染症の治療のための弱毒化微生物
Angerman et al. Comparative efficacy and toxicity of a ribosomal vaccine, acetone-killed cells, lipopolysaccharide, and a live cell vaccine prepared from Salmonella typhhimurium
CN102971008B (zh) 降低弯曲菌属感染的疫苗和方法
US20080069844A1 (en) Mucosal Vaccine Adjuvants Containing Bacterial Flagellins as an Active Component
JP4982009B2 (ja) ナイセリアワクチン組成物および方法
Roberts et al. Protection of mice against respiratory Bordetella pertussis infection by intranasal immunization with P. 69 and FHA
US20170072034A1 (en) Therapeutic cancer vaccine targeted to haah (aspartyl-[asparaginyl]-beta-hydroxylase)
CN114099659A (zh) 结核分枝杆菌Rv0934抗原蛋白、其抗原表位肽及其应用
US6660261B1 (en) Bordetella strain expressing the FHA hybrid, liposomes and vaccines
US7081244B2 (en) Neisserial vaccine compositions and methods
KR101991577B1 (ko) 다수의 에피토프로 구성된 재조합 항원 단백질 및 이의 제조방법
JP2009029825A (ja) 抗原
EP0358692B1 (en) Cholera vaccines
CN111150839A (zh) 一种用于免疫接种的组合物及其制备方法
CN118108815B (zh) 结核分枝杆菌多免疫原抗原、编码其的mRNA、应用
CN115340997B (zh) 一种基于Lpp引导序列靶向呈递和高效表达外源抗原的重组沙门菌构建方法
CN118930658A (zh) 一种基于细菌样颗粒的炭疽芽胞杆菌疫苗
CN119185523A (zh) 预防b群脑膜炎球菌感染的广谱多联亚单位疫苗及其用途
WO2005096823A1 (en) Vaccine for nontypeable haemophilus influenzae infection

Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent
MM4A Annulment or lapse of patent due to non-payment of fees