TW442287B - Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) - Google Patents

Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) Download PDF

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Publication number
TW442287B
TW442287B TW085104431A TW85104431A TW442287B TW 442287 B TW442287 B TW 442287B TW 085104431 A TW085104431 A TW 085104431A TW 85104431 A TW85104431 A TW 85104431A TW 442287 B TW442287 B TW 442287B
Authority
TW
Taiwan
Prior art keywords
acid
medicine
group
diethyl
formula
Prior art date
Application number
TW085104431A
Other languages
English (en)
Chinese (zh)
Inventor
Leslie G Humber
Gerald L Reuter
Original Assignee
American Home Produits Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Produits Corp filed Critical American Home Produits Corp
Application granted granted Critical
Publication of TW442287B publication Critical patent/TW442287B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW085104431A 1995-06-13 1996-04-13 Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) TW442287B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16995P 1995-06-13 1995-06-13
CN96112209A CN1155417A (zh) 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂

Publications (1)

Publication Number Publication Date
TW442287B true TW442287B (en) 2001-06-23

Family

ID=37709653

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085104431A TW442287B (en) 1995-06-13 1996-04-13 Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)

Country Status (22)

Country Link
US (1) US5780046A (enEXAMPLES)
EP (1) EP0753296A3 (enEXAMPLES)
JP (1) JPH092949A (enEXAMPLES)
CN (1) CN1155417A (enEXAMPLES)
AR (1) AR002442A1 (enEXAMPLES)
AU (1) AU715367B2 (enEXAMPLES)
BR (1) BR9602759A (enEXAMPLES)
CA (1) CA2178691A1 (enEXAMPLES)
CZ (1) CZ170396A3 (enEXAMPLES)
EA (1) EA000046B1 (enEXAMPLES)
EE (1) EE9600068A (enEXAMPLES)
HU (1) HUP9601619A3 (enEXAMPLES)
IL (1) IL118637A (enEXAMPLES)
IN (1) IN182039B (enEXAMPLES)
MA (1) MA23908A1 (enEXAMPLES)
NO (1) NO962490L (enEXAMPLES)
NZ (1) NZ286790A (enEXAMPLES)
PL (1) PL314731A1 (enEXAMPLES)
SK (1) SK74496A3 (enEXAMPLES)
TR (1) TR199600498A2 (enEXAMPLES)
TW (1) TW442287B (enEXAMPLES)
ZA (1) ZA964929B (enEXAMPLES)

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CN101077343B (zh) * 2006-12-12 2010-06-30 蚌埠丰原涂山制药有限公司 右旋布洛芬颗粒及制备方法
EA200901188A1 (ru) * 2007-07-23 2010-04-30 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Органолептически приемлемые дозированные лекарственные формы индольных агонистов серотониновых рецепторов для перорального применения и способы их применения
US8445545B2 (en) * 2008-05-07 2013-05-21 Nicholas DeSica Pharmaceutical composition, method of preparation and methods of treating aches/pains
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Also Published As

Publication number Publication date
EP0753296A2 (en) 1997-01-15
AU5588196A (en) 1997-01-02
IL118637A0 (en) 1996-10-16
NO962490D0 (no) 1996-06-12
NO962490L (no) 1996-12-16
EA199600028A2 (ru) 1996-12-30
CN1155417A (zh) 1997-07-30
PL314731A1 (en) 1996-12-23
ZA964929B (en) 1997-12-10
IL118637A (en) 1999-10-28
HU9601619D0 (en) 1996-08-28
US5780046A (en) 1998-07-14
IN182039B (enEXAMPLES) 1998-12-12
CZ170396A3 (en) 1997-04-16
CA2178691A1 (en) 1996-12-14
EA000046B1 (ru) 1998-04-30
TR199600498A2 (tr) 1997-03-21
JPH092949A (ja) 1997-01-07
EE9600068A (et) 1996-12-16
AU715367B2 (en) 2000-02-03
NZ286790A (en) 1998-02-26
MA23908A1 (fr) 1996-12-31
EA199600028A3 (ru) 1997-03-31
AR002442A1 (es) 1998-03-11
EP0753296A3 (en) 1997-04-23
HUP9601619A3 (en) 1999-05-28
BR9602759A (pt) 1998-04-22
SK74496A3 (en) 1997-04-09
HUP9601619A2 (en) 1997-02-28

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