TW333525B - New perhydroisoindole derivatives, their preparation and the pharmaceutical compositions which contain them the invention relates to perhydroisoindole derivatives of general formula (I), and their salts when they exist advantageously as neurokinin A antagonists. - Google Patents
New perhydroisoindole derivatives, their preparation and the pharmaceutical compositions which contain them the invention relates to perhydroisoindole derivatives of general formula (I), and their salts when they exist advantageously as neurokinin A antagonists.Info
- Publication number
- TW333525B TW333525B TW083102916A TW83102916A TW333525B TW 333525 B TW333525 B TW 333525B TW 083102916 A TW083102916 A TW 083102916A TW 83102916 A TW83102916 A TW 83102916A TW 333525 B TW333525 B TW 333525B
- Authority
- TW
- Taiwan
- Prior art keywords
- perhydroisoindole derivatives
- general formula
- neurokinin
- antagonists
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9303965A FR2703679B1 (fr) | 1993-04-05 | 1993-04-05 | Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW333525B true TW333525B (en) | 1998-06-11 |
Family
ID=9445733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW083102916A TW333525B (en) | 1993-04-05 | 1994-04-02 | New perhydroisoindole derivatives, their preparation and the pharmaceutical compositions which contain them the invention relates to perhydroisoindole derivatives of general formula (I), and their salts when they exist advantageously as neurokinin A antagonists. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5631279A (zh) |
| EP (1) | EP0693059B1 (zh) |
| JP (1) | JPH08508283A (zh) |
| KR (1) | KR960701842A (zh) |
| AT (1) | ATE150014T1 (zh) |
| AU (1) | AU6506894A (zh) |
| CA (1) | CA2158663A1 (zh) |
| CZ (1) | CZ258495A3 (zh) |
| DE (1) | DE69402058T2 (zh) |
| DK (1) | DK0693059T3 (zh) |
| ES (1) | ES2099601T3 (zh) |
| FI (1) | FI954730A (zh) |
| FR (1) | FR2703679B1 (zh) |
| GR (1) | GR3022798T3 (zh) |
| HU (1) | HUT74089A (zh) |
| IL (1) | IL109217A0 (zh) |
| NO (1) | NO953913L (zh) |
| PL (1) | PL310948A1 (zh) |
| SK (1) | SK123595A3 (zh) |
| TW (1) | TW333525B (zh) |
| WO (1) | WO1994022822A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW432061B (en) * | 1994-08-09 | 2001-05-01 | Pfizer Res & Dev | Lactams |
| FR2737495B1 (fr) * | 1995-08-02 | 1997-08-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent |
| GB9816897D0 (en) * | 1998-08-04 | 1998-09-30 | Merck Sharp & Dohme | Therapeutic use |
| DE102006007882A1 (de) | 2006-02-21 | 2007-08-30 | Bayer Cropscience Ag | Cycloalkyl-phenylsubstituierte cyclische Ketoenole |
| AU2012372019B2 (en) * | 2011-12-22 | 2017-06-15 | Connexios Life Sciences Pvt. Ltd. | Cyclic amide derivatives as inhibitors of 11 - beta - hydroxysteroid dehydrogenase and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6372689A (ja) * | 1986-09-16 | 1988-04-02 | Taisho Pharmaceut Co Ltd | （−）−α−カイニン酸の中間体およびその製造方法 |
| FR2654725B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2654726B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone et leur preparation. |
| FR2676442B1 (fr) * | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676443B1 (fr) * | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
| FR2689889B1 (fr) * | 1992-04-10 | 1994-06-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole, et leur preparation. |
| FR2689888B1 (fr) * | 1992-04-10 | 1994-06-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
-
1993
- 1993-04-05 FR FR9303965A patent/FR2703679B1/fr not_active Expired - Fee Related
-
1994
- 1994-04-01 DE DE69402058T patent/DE69402058T2/de not_active Expired - Fee Related
- 1994-04-01 PL PL94310948A patent/PL310948A1/xx unknown
- 1994-04-01 CA CA002158663A patent/CA2158663A1/fr not_active Abandoned
- 1994-04-01 AT AT94912582T patent/ATE150014T1/de not_active IP Right Cessation
- 1994-04-01 CZ CZ952584A patent/CZ258495A3/cs unknown
- 1994-04-01 US US08/448,402 patent/US5631279A/en not_active Expired - Fee Related
- 1994-04-01 SK SK1235-95A patent/SK123595A3/sk unknown
- 1994-04-01 ES ES94912582T patent/ES2099601T3/es not_active Expired - Lifetime
- 1994-04-01 WO PCT/FR1994/000371 patent/WO1994022822A1/fr not_active Application Discontinuation
- 1994-04-01 AU AU65068/94A patent/AU6506894A/en not_active Abandoned
- 1994-04-01 HU HU9502902A patent/HUT74089A/hu unknown
- 1994-04-01 EP EP94912582A patent/EP0693059B1/fr not_active Expired - Lifetime
- 1994-04-01 KR KR1019950704299A patent/KR960701842A/ko not_active Application Discontinuation
- 1994-04-01 JP JP6521762A patent/JPH08508283A/ja active Pending
- 1994-04-01 DK DK94912582.7T patent/DK0693059T3/da active
- 1994-04-02 TW TW083102916A patent/TW333525B/zh active
- 1994-04-04 IL IL10921794A patent/IL109217A0/xx unknown
-
1995
- 1995-10-02 NO NO953913A patent/NO953913L/no unknown
- 1995-10-04 FI FI954730A patent/FI954730A/fi not_active Application Discontinuation
-
1997
- 1997-03-13 GR GR960403190T patent/GR3022798T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL109217A0 (en) | 1994-07-31 |
| FI954730A0 (fi) | 1995-10-04 |
| WO1994022822A1 (fr) | 1994-10-13 |
| CZ258495A3 (en) | 1996-01-17 |
| KR960701842A (ko) | 1996-03-28 |
| ES2099601T3 (es) | 1997-05-16 |
| EP0693059B1 (fr) | 1997-03-12 |
| HUT74089A (en) | 1996-11-28 |
| DK0693059T3 (da) | 1997-09-15 |
| HU9502902D0 (en) | 1995-11-28 |
| EP0693059A1 (fr) | 1996-01-24 |
| FI954730A (fi) | 1995-11-17 |
| DE69402058T2 (de) | 1997-09-18 |
| PL310948A1 (en) | 1996-01-08 |
| AU6506894A (en) | 1994-10-24 |
| ATE150014T1 (de) | 1997-03-15 |
| JPH08508283A (ja) | 1996-09-03 |
| FR2703679B1 (fr) | 1995-06-23 |
| NO953913D0 (no) | 1995-10-02 |
| US5631279A (en) | 1997-05-20 |
| CA2158663A1 (fr) | 1994-10-13 |
| GR3022798T3 (en) | 1997-06-30 |
| FR2703679A1 (fr) | 1994-10-14 |
| SK123595A3 (en) | 1996-06-05 |
| DE69402058D1 (de) | 1997-04-17 |
| NO953913L (no) | 1995-10-02 |
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