NO981689L - Naftylpiperasinderivater - Google Patents

Naftylpiperasinderivater

Info

Publication number
NO981689L
NO981689L NO981689A NO981689A NO981689L NO 981689 L NO981689 L NO 981689L NO 981689 A NO981689 A NO 981689A NO 981689 A NO981689 A NO 981689A NO 981689 L NO981689 L NO 981689L
Authority
NO
Norway
Prior art keywords
group
receptors
short chain
compounds
hydrogen
Prior art date
Application number
NO981689A
Other languages
English (en)
Other versions
NO981689D0 (no
Inventor
Aurelio Orjales-Venero
Neftaly Garcia-Dominguez
Original Assignee
Espanola Prod Quimicos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Espanola Prod Quimicos filed Critical Espanola Prod Quimicos
Publication of NO981689D0 publication Critical patent/NO981689D0/no
Publication of NO981689L publication Critical patent/NO981689L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Nye naftylpiperazinderivater med generell formel (I) hvori Rj og R2, like eller forskjellige, kan være hydrogen, en kortkjedet alkyl- gruppe, halogen, en nitrogruppe, en aminogruppe, en acylaminogruppe og en kortkjedet alkoksygruppe; n kan ha verdier mellom 2 og 5; og R3 kan være et metoksylradikal, et fluoratom og et hydrogenatom, og deres addisjonssalter med farmasøytisk akseptable syrer. Forbindelsene oppviser affinitet for serotonin-5HT1A- og 5HT2-reseptorer og for dopamin-D2-reseptorer, og kan være anvendelige som antipsykotiske midler. Fremstilling av forbindelsene er også beskrevet.
NO981689A 1997-04-16 1998-04-15 Naftylpiperasinderivater NO981689L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9700812 1997-04-16

Publications (2)

Publication Number Publication Date
NO981689D0 NO981689D0 (no) 1998-04-15
NO981689L true NO981689L (no) 1998-10-19

Family

ID=8298980

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981689A NO981689L (no) 1997-04-16 1998-04-15 Naftylpiperasinderivater

Country Status (15)

Country Link
EP (1) EP0875512A3 (no)
JP (1) JPH10287658A (no)
KR (1) KR19980081366A (no)
CN (1) CN1197067A (no)
AR (1) AR017500A1 (no)
AU (1) AU6192298A (no)
BR (1) BR9801075A (no)
CA (1) CA2234789A1 (no)
CO (1) CO4940468A1 (no)
CZ (1) CZ111898A3 (no)
HR (1) HRP980204A2 (no)
HU (1) HUP9800889A1 (no)
NO (1) NO981689L (no)
PL (1) PL325816A1 (no)
ZA (1) ZA983168B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2162731B1 (es) * 1999-06-04 2003-02-16 Faes Fabrica Espanola De Produ Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.
US20030073692A1 (en) 2001-08-07 2003-04-17 Pharmacia & Upjohn S.P.A. Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
WO2005113527A1 (en) * 2004-05-21 2005-12-01 Pfizer Products Inc. Tetrahydronaphthyl- piperazines as 5-ht1b antagonists, inverse agonists and partial agonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1222867B (it) * 1987-10-12 1990-09-12 Zambon Spa Ftalazino derivati ad attivita' farmaceutica
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
FR2655988B1 (fr) * 1989-12-20 1994-05-20 Adir Cie Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2680172B1 (fr) * 1991-08-05 1993-11-19 Fabre Medicament Pierre Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
FR2707294B1 (fr) * 1993-07-06 1995-09-29 Pf Medicament Nouveaux dérivés de la 3,5-dioxo-(2H,4H)-1,2,4-triazine, leur préparation et leur application en thérapeutique humaine.
FR2727682A1 (fr) * 1994-12-02 1996-06-07 Pf Medicament Nouveaux derives de 3,5-dioxo-(2h,4h)-1,2,4-triazines, leur preparation et leur application a titre de medicament

Also Published As

Publication number Publication date
CZ111898A3 (cs) 1998-11-11
EP0875512A3 (en) 1999-04-07
AU6192298A (en) 1998-10-22
CA2234789A1 (en) 1998-10-16
PL325816A1 (en) 1998-10-26
CN1197067A (zh) 1998-10-28
EP0875512A2 (en) 1998-11-04
BR9801075A (pt) 2000-02-08
AR017500A1 (es) 2001-09-12
HRP980204A2 (en) 1999-02-28
CO4940468A1 (es) 2000-07-24
JPH10287658A (ja) 1998-10-27
NO981689D0 (no) 1998-04-15
HUP9800889A1 (hu) 2000-11-28
HU9800889D0 (en) 1998-06-29
ZA983168B (en) 1998-10-20
KR19980081366A (ko) 1998-11-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application