TW202333749A - 補體因子ｂ（ｃｆｂ）ｉｒｎａ組成物及其使用方法 - Google Patents

補體因子ｂ（ｃｆｂ）ｉｒｎａ組成物及其使用方法

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TW202333749A
TW202333749A TW111140910A TW111140910A TW202333749A TW 202333749 A TW202333749 A TW 202333749A TW 111140910 A TW111140910 A TW 111140910A TW 111140910 A TW111140910 A TW 111140910A TW 202333749 A TW202333749 A TW 202333749A
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nucleotide
nucleotides
ome
strand
dsrna agent
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TW111140910A
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English (en)
Chinese (zh)
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詹姆斯Ｄ 麥金尼奇
馬克Ｋ 史奇蓋爾
艾登 卡斯特瑞諾
伊萊恩 菲什列維奇
克里斯蒂娜 尤修斯
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美商艾拉倫製藥股份有限公司
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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TW111140910A 2021-10-29 2022-10-27 補體因子ｂ（ｃｆｂ）ｉｒｎａ組成物及其使用方法 TW202333749A (zh)

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US202163273215P 2021-10-29 2021-10-29
US63/273,215 2021-10-29

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US (2) US11965166B2 (https=)
EP (1) EP4423273A1 (https=)
JP (1) JP2024541989A (https=)
KR (1) KR20240095325A (https=)
CN (1) CN118302525A (https=)
AR (1) AR127477A1 (https=)
AU (1) AU2022378567A1 (https=)
CA (1) CA3234636A1 (https=)
CL (1) CL2024001319A1 (https=)
CO (1) CO2024006046A2 (https=)
IL (1) IL312399A (https=)
MX (1) MX2024004750A (https=)
TW (1) TW202333749A (https=)
WO (1) WO2023076451A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202134435A (zh) 2019-10-22 2021-09-16 美商阿尼拉製藥公司 補體成分ｃ３ ｉｒｎａ組成物及其使用方法
PE20241340A1 (es) 2021-11-24 2024-07-03 Adarx Pharmaceuticals Inc Composiciones moduladoras de complemento del factor b y metodos de uso de estas
EP4638743A2 (en) * 2022-12-19 2025-10-29 Sanegene Bio USA Inc. Small interfering rna targeting cfb and uses thereof
WO2024197017A2 (en) * 2023-03-21 2024-09-26 Arrowhead Pharmaceuticals, Inc. Rnai agents for inhibiting expression of complement factor b (cfb) pharmaceutical compositions thereof, and methods of use
WO2025113592A1 (zh) * 2023-12-01 2025-06-05 厦门甘宝利生物医药有限公司 一种抑制补体系统基因表达的rna抑制剂及其应用
WO2025140402A1 (zh) * 2023-12-28 2025-07-03 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
US20250382616A1 (en) * 2024-06-18 2025-12-18 Sanegene Bio Usa Inc. Small interfering rna targeting cfb and uses thereof
WO2026052075A1 (zh) * 2024-09-06 2026-03-12 湖北生物医药产业技术研究院有限公司 抑制CFB基因表达的siRNA及其用途
WO2026052079A1 (zh) * 2024-09-07 2026-03-12 苏州瑞博生物技术股份有限公司 寡核苷酸、寡核苷酸缀合物及组合物和用途
WO2026056988A1 (en) * 2024-09-11 2026-03-19 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Sirna, conjugate which contain sirna, pharmaceutical composition and uses thereof

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