TW202317599A - 具有抗病毒活性之胜肽、包含該胜肽之抗病毒劑、該抗病毒劑之製造方法 - Google Patents

具有抗病毒活性之胜肽、包含該胜肽之抗病毒劑、該抗病毒劑之製造方法 Download PDF

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TW202317599A
TW202317599A TW111125356A TW111125356A TW202317599A TW 202317599 A TW202317599 A TW 202317599A TW 111125356 A TW111125356 A TW 111125356A TW 111125356 A TW111125356 A TW 111125356A TW 202317599 A TW202317599 A TW 202317599A
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amino acid
residue
cov
sars
sequence
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TW111125356A
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Chinese (zh)
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藤吉好則
中村駿
野村莉紗
谷村幸宏
亀川亜希子
沼本修孝
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國立大學法人東京醫科齒科大學
日商塞斯匹亞股份有限公司
日商衛材R&D企管股份有限公司
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Publication of TW202317599A publication Critical patent/TW202317599A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
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    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485Exopeptidases (3.4.11-3.4.19)
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    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/17Metallocarboxypeptidases (3.4.17)
    • C12Y304/17023Angiotensin-converting enzyme 2 (3.4.17.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
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  • Engineering & Computer Science (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
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  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW111125356A 2021-07-07 2022-07-06 具有抗病毒活性之胜肽、包含該胜肽之抗病毒劑、該抗病毒劑之製造方法 TW202317599A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2021-113006 2021-07-07
JP2021113006 2021-07-07
JP2021145370 2021-09-07
JP2021-145370 2021-09-07
JP2022-103949 2022-06-28
JP2022103949 2022-06-28

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Publication Number Publication Date
TW202317599A true TW202317599A (zh) 2023-05-01

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TW111125356A TW202317599A (zh) 2021-07-07 2022-07-06 具有抗病毒活性之胜肽、包含該胜肽之抗病毒劑、該抗病毒劑之製造方法

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US (1) US20240309059A1 (https=)
EP (1) EP4368631A4 (https=)
JP (1) JP7687637B2 (https=)
TW (1) TW202317599A (https=)
WO (1) WO2023282281A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026068449A1 (en) * 2024-09-24 2026-04-02 Universite De Geneve Antibody- like binding molecules and uses thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106559844B (zh) 2015-09-25 2020-03-24 电信科学技术研究院 一种上行传输资源调度及上行传输方法、装置
JP6974512B2 (ja) 2020-01-21 2021-12-01 本田技研工業株式会社 車両のフロア構造
KR20230017215A (ko) * 2020-05-27 2023-02-03 유니버시티 오브 워싱턴 드 노보 설계한 단백질 스위치에 기반한 모듈형의 일반화 가능한 바이오센서 플랫폼
EP4182027A1 (en) * 2020-07-14 2023-05-24 University of Washington Sars-cov-2 inhibitors
JP2022103949A (ja) 2020-12-28 2022-07-08 セイコーエプソン株式会社 インクセット及び記録方法

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EP4368631A4 (en) 2025-08-13
JP7687637B2 (ja) 2025-06-03
WO2023282281A1 (ja) 2023-01-12
EP4368631A1 (en) 2024-05-15
US20240309059A1 (en) 2024-09-19
JPWO2023282281A1 (https=) 2023-01-12

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