TW202302137A - 育毛劑 - Google Patents
育毛劑 Download PDFInfo
- Publication number
- TW202302137A TW202302137A TW111107182A TW111107182A TW202302137A TW 202302137 A TW202302137 A TW 202302137A TW 111107182 A TW111107182 A TW 111107182A TW 111107182 A TW111107182 A TW 111107182A TW 202302137 A TW202302137 A TW 202302137A
- Authority
- TW
- Taiwan
- Prior art keywords
- hair
- diaminobutyryl
- palmitoyl dipeptide
- adenosine
- hydroxythreonine
- Prior art date
Links
- 210000004209 hair Anatomy 0.000 title claims abstract description 80
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 claims abstract description 90
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims abstract description 85
- 210000004919 hair shaft Anatomy 0.000 claims abstract description 53
- 239000002126 C01EB10 - Adenosine Substances 0.000 claims abstract description 45
- 229960005305 adenosine Drugs 0.000 claims abstract description 45
- 239000004480 active ingredient Substances 0.000 claims abstract description 28
- 230000012010 growth Effects 0.000 claims abstract description 23
- 230000003779 hair growth Effects 0.000 claims abstract description 22
- 210000004709 eyebrow Anatomy 0.000 claims abstract description 10
- 210000000720 eyelash Anatomy 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 70
- JBNUARFQOCGDRK-GBXIJSLDSA-N 4-hydroxy-L-threonine Chemical compound [O-]C(=O)[C@@H]([NH3+])[C@H](O)CO JBNUARFQOCGDRK-GBXIJSLDSA-N 0.000 claims description 38
- 238000002360 preparation method Methods 0.000 claims description 27
- SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 claims description 24
- 239000002253 acid Substances 0.000 claims description 15
- 230000035784 germination Effects 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 235000010855 food raising agent Nutrition 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 5
- -1 adenyl Glycosides Chemical class 0.000 claims description 2
- 229940124277 aminobutyric acid Drugs 0.000 claims description 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims description 2
- 229930182470 glycoside Natural products 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 32
- 230000014509 gene expression Effects 0.000 abstract description 17
- 230000001737 promoting effect Effects 0.000 abstract description 13
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000003752 improving hair Effects 0.000 abstract description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 2
- BVYVWYKOCOGULA-JBUMCTQMSA-N (2s,3r)-2-[[(2s)-4-amino-2-[[(2s)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]butanoyl]amino]-3-hydroxybutanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O BVYVWYKOCOGULA-JBUMCTQMSA-N 0.000 abstract 1
- QJQNWKPSKDLCOX-UHFFFAOYSA-N 3,3-diamino-2-hydroxybutanoic acid Chemical compound NC(C(C(=O)O)O)(C)N QJQNWKPSKDLCOX-UHFFFAOYSA-N 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000004761 scalp Anatomy 0.000 description 29
- 210000004027 cell Anatomy 0.000 description 20
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 description 17
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 17
- 239000000203 mixture Substances 0.000 description 17
- 230000002500 effect on skin Effects 0.000 description 13
- 230000031774 hair cycle Effects 0.000 description 10
- 230000004570 RNA-binding Effects 0.000 description 8
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 7
- 239000002299 complementary DNA Substances 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 7
- 239000003814 drug Substances 0.000 description 7
- 239000004615 ingredient Substances 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 201000004384 Alopecia Diseases 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 101150112014 Gapdh gene Proteins 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000002552 dosage form Substances 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 229960003632 minoxidil Drugs 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 238000003753 real-time PCR Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 239000000654 additive Substances 0.000 description 3
- 230000001747 exhibiting effect Effects 0.000 description 3
- 230000003648 hair appearance Effects 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 230000003658 preventing hair loss Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000002441 reversible effect Effects 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- MSTCKFAZFCWNSK-NSVAZKTRSA-N (2s)-4-amino-2-[[(2s)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]butanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCN)C(O)=O MSTCKFAZFCWNSK-NSVAZKTRSA-N 0.000 description 2
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- 108090000695 Cytokines Proteins 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 2
- 208000001840 Dandruff Diseases 0.000 description 2
- 206010013786 Dry skin Diseases 0.000 description 2
- 239000004131 EU approved raising agent Substances 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 102100028071 Fibroblast growth factor 7 Human genes 0.000 description 2
- 108090000385 Fibroblast growth factor 7 Proteins 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 230000003698 anagen phase Effects 0.000 description 2
- 206010068168 androgenetic alopecia Diseases 0.000 description 2
- 201000002996 androgenic alopecia Diseases 0.000 description 2
- 230000006907 apoptotic process Effects 0.000 description 2
- 238000010804 cDNA synthesis Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 230000003676 hair loss Effects 0.000 description 2
- 208000024963 hair loss Diseases 0.000 description 2
- 239000008266 hair spray Substances 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 239000011259 mixed solution Substances 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 230000003797 telogen phase Effects 0.000 description 2
- 210000003556 vascular endothelial cell Anatomy 0.000 description 2
- 239000011534 wash buffer Substances 0.000 description 2
- BLCJBICVQSYOIF-UHFFFAOYSA-N 2,2-diaminobutanoic acid Chemical compound CCC(N)(N)C(O)=O BLCJBICVQSYOIF-UHFFFAOYSA-N 0.000 description 1
- 241001340526 Chrysoclista linneella Species 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 101000993347 Gallus gallus Ciliary neurotrophic factor Proteins 0.000 description 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 1
- 238000011529 RT qPCR Methods 0.000 description 1
- 102000006382 Ribonucleases Human genes 0.000 description 1
- 108010083644 Ribonucleases Proteins 0.000 description 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
- 239000004473 Threonine Substances 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 229920006318 anionic polymer Polymers 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000013592 cell lysate Substances 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000002734 clay mineral Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000012149 elution buffer Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 229940098448 fibroblast growth factor 7 Drugs 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 210000004186 follicle cell Anatomy 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 229920000831 ionic polymer Polymers 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000012139 lysis buffer Substances 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000001817 pituitary effect Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000003405 preventing effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 210000004500 stellate cell Anatomy 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000008728 vascular permeability Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021-031138 | 2021-02-26 | ||
| JP2021031138 | 2021-02-26 | ||
| WOPCT/JP2022/008010 | 2022-02-25 | ||
| PCT/JP2022/008010 WO2022181786A1 (ja) | 2021-02-26 | 2022-02-25 | 育毛剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202302137A true TW202302137A (zh) | 2023-01-16 |
Family
ID=83047567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW111107182A TW202302137A (zh) | 2021-02-26 | 2022-02-25 | 育毛劑 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240139276A1 (https=) |
| JP (1) | JPWO2022181786A1 (https=) |
| KR (1) | KR20230152072A (https=) |
| CN (1) | CN116916882A (https=) |
| TW (1) | TW202302137A (https=) |
| WO (1) | WO2022181786A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240023618A (ko) * | 2021-06-19 | 2024-02-22 | 가부시키가이샤 아쥬반트 홀딩스 | 육모제 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1231000A (en) * | 1998-10-26 | 2000-05-15 | University Of Massachusetts | Treatment of skin with adenosine or adenosine analog |
| US20070299032A1 (en) | 2003-11-11 | 2007-12-27 | Shiseido Company, Ltd. | Method and Composition for Thickening Hair |
| BRPI0621609B1 (pt) | 2006-04-28 | 2017-12-19 | Dsm Ip Assets B.V. | Composition, non-therapeutic use of the composition and compounds |
| JP5754053B2 (ja) * | 2009-04-22 | 2015-07-22 | ディーエスエム アイピー アセッツ ビー.ブイ. | 新規な組成物 |
| CN101716130A (zh) * | 2009-12-07 | 2010-06-02 | 广东拉芳日化有限公司 | 一种含有水包油纳米包裹活性成份的头发护理用品组合物 |
| JP2012126671A (ja) * | 2010-12-15 | 2012-07-05 | Ltt Bio-Pharma Co Ltd | 育毛剤 |
| JP2013151480A (ja) * | 2011-12-26 | 2013-08-08 | Rohto Pharmaceutical Co Ltd | 外用組成物の安定化方法 |
| WO2015157692A1 (en) * | 2014-04-10 | 2015-10-15 | Cgtn C.V. | Skin care composition comprising plant extracts |
| CN110368397A (zh) * | 2019-08-21 | 2019-10-25 | 上海棠美生物科技有限公司 | 一种防止脱发促进毛发生长的外用组合物及其制备方法 |
| CN117695372A (zh) * | 2019-10-18 | 2024-03-15 | 安佳榜控股股份公司 | 头皮保养剂 |
| CN110772446B (zh) * | 2019-12-19 | 2023-08-22 | 深圳市维琪科技股份有限公司 | 一种油包水体系皮肤修复多肽组合物 |
| CN111329779B (zh) * | 2020-03-23 | 2022-09-13 | 烟台中科恩吉科创新产业园管理有限公司 | 一种促毛发增长的活性肽组合物及其应用 |
-
2022
- 2022-02-25 US US18/278,728 patent/US20240139276A1/en active Pending
- 2022-02-25 JP JP2023502551A patent/JPWO2022181786A1/ja active Pending
- 2022-02-25 KR KR1020237032280A patent/KR20230152072A/ko active Pending
- 2022-02-25 TW TW111107182A patent/TW202302137A/zh unknown
- 2022-02-25 CN CN202280008688.0A patent/CN116916882A/zh active Pending
- 2022-02-25 WO PCT/JP2022/008010 patent/WO2022181786A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2022181786A1 (https=) | 2022-09-01 |
| WO2022181786A1 (ja) | 2022-09-01 |
| KR20230152072A (ko) | 2023-11-02 |
| US20240139276A1 (en) | 2024-05-02 |
| CN116916882A (zh) | 2023-10-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2005044205A1 (ja) | 毛髪の太毛化の方法及び組成物 | |
| US9993518B2 (en) | Association of a tetrapeptide and a glyceryl ester for treating androgenic alopecia | |
| TW202317077A (zh) | 育毛劑 | |
| JP4681230B2 (ja) | フィトスフィンゴシンのスリミング剤としての化粧的使用、及び、フィトスフィンゴシンを含む化粧組成物 | |
| TW202302137A (zh) | 育毛劑 | |
| US10835468B2 (en) | Particular pyridinedicarboxylic acid derivative/antioxidant combination | |
| TW202317078A (zh) | 育毛劑 | |
| TW202317076A (zh) | 育毛劑 | |
| FR2984129A1 (fr) | Utilisation de la proteine mmp-12 dans la prevention et/ou le traitement des etats pelliculaires du cuir chevelu | |
| HK40092879A (zh) | 育毛剂 | |
| JP2023521275A (ja) | 脱毛防止及び発毛促進用組成物 | |
| US20200276154A1 (en) | Composition for promoting adipocyte differentiation or adiponectin, comprising trimethoxy phenyl compound | |
| TW202300136A (zh) | 育毛劑 | |
| HK40102133A (zh) | 育毛剂 | |
| HK40101945A (zh) | 育毛剂 | |
| HK40102132A (zh) | 育毛剂 | |
| TW202228757A (zh) | 育毛劑 | |
| HK40092880A (zh) | 育毛剂 | |
| WO2025084438A1 (ja) | 硫酸転移酵素産生促進剤および硫酸転移酵素活性促進剤 | |
| EP4525823B1 (en) | Olfactory receptor 2a4/7 agonist for promoting hair growth and improving aesthetic aspect | |
| JP7739300B2 (ja) | 脱毛防止及び発毛促進用組成物 | |
| HK40071981B (zh) | 育毛剂 | |
| JP2023025132A (ja) | スカルプケア剤 | |
| WO2022124212A1 (ja) | 毛髪改善のための組成物 | |
| KR20160050898A (ko) | Atp를 함유하는 발모 및 육모 촉진용 조성물 |