TW202214858A - 脫靶活性降低的修飾siRNA - Google Patents

脫靶活性降低的修飾siRNA Download PDF

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TW202214858A
TW202214858A TW110128792A TW110128792A TW202214858A TW 202214858 A TW202214858 A TW 202214858A TW 110128792 A TW110128792 A TW 110128792A TW 110128792 A TW110128792 A TW 110128792A TW 202214858 A TW202214858 A TW 202214858A
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methoxy
sirna
nucleotide
alkynyl
alkenyl
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TW110128792A
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黃金宇
羅敏
尹科
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大陸商上海拓界生物醫藥科技有限公司
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TW110128792A 2020-08-04 2021-08-04 脫靶活性降低的修飾siRNA TW202214858A (zh)

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CN202010772542 2020-08-04
CN202010772542.6 2020-08-04
CN202110244977 2021-03-05
CN202110244977.8 2021-03-05
CN202110361502.7 2021-04-02
CN202110361502 2021-04-02

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KR (1) KR20230043195A (enExample)
CN (1) CN115955973A (enExample)
BR (1) BR112023002080A2 (enExample)
CA (1) CA3190097A1 (enExample)
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EP4467645A4 (en) * 2022-01-20 2026-01-21 Tuojie Biotech Shanghai Co Ltd DOUBLE-STRANDED RNA, ITS USES AND PREPARATION PROCESS
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WO2026002138A1 (zh) * 2024-06-27 2026-01-02 成都新泽利医药科技有限公司 特定修饰的双链寡核苷酸及其组合物
CN119410644A (zh) * 2025-01-08 2025-02-11 北京安龙生物医药有限公司 修饰的双链寡核苷酸及其缀合物和组合物
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EP4194553A4 (en) 2024-11-13
ZA202303275B (en) 2025-12-17
US20230287418A1 (en) 2023-09-14
KR20230043195A (ko) 2023-03-30
CA3190097A1 (en) 2022-02-10
BR112023002080A2 (pt) 2023-04-25
WO2022028462A1 (zh) 2022-02-10
EP4194553A1 (en) 2023-06-14
CN115955973A (zh) 2023-04-11
JP2023536320A (ja) 2023-08-24

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