TW202208337A - Ｅｎｐｐ１之亞胺基硫烷酮抑制劑 - Google Patents

Ｅｎｐｐ１之亞胺基硫烷酮抑制劑 Download PDF

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TW202208337A
TW202208337A TW110115908A TW110115908A TW202208337A TW 202208337 A TW202208337 A TW 202208337A TW 110115908 A TW110115908 A TW 110115908A TW 110115908 A TW110115908 A TW 110115908A TW 202208337 A TW202208337 A TW 202208337A
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compound
pharmaceutically acceptable
acceptable salt
methyl
mmol
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TW110115908A
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Chinese (zh)
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德里克 Ａ 柯根
莎拉 貝蒂戈爾
新森 蘇
皮奧特 尼采爾
伯科姆 里昂 范
羅格 福爾默
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美商佛拉斯托醫療公司
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    • C07D495/10—Spiro-condensed systems
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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TW110115908A 2020-05-04 2021-05-03 Ｅｎｐｐ１之亞胺基硫烷酮抑制劑 TW202208337A (zh)

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WO2021231726A1 (en) * 2020-05-14 2021-11-18 Vir Biotechnology, Inc. Enpp1 modulators and uses thereof
TW202214640A (zh) 2020-06-16 2022-04-16 美商佛拉斯托醫療公司 Ｅｎｐｐ１之雜環抑制劑
WO2022091048A1 (en) 2020-10-30 2022-05-05 Integral Biosciences Private Limited Ectonucleotide pyrophosphatase-phosphodiesterase-1 (enpp1) inhibitors and uses thereof
WO2023086638A1 (en) * 2021-11-15 2023-05-19 Vir Biotechnology, Inc. Enpp1 modulators and uses thereof
JP2024545511A (ja) * 2021-12-09 2024-12-09 バラ セラピューティクス，インコーポレイテッド メニン－ｍｌｌ相互作用の阻害剤
WO2023168240A1 (en) * 2022-03-02 2023-09-07 The Regents Of The University Of California Small molecule inhibitors of enpp1
EP4514331A1 (en) 2022-04-29 2025-03-05 Petragen, Inc. Inhibitors of enpp1 and modulation of bone growth
WO2023225001A1 (en) * 2022-05-16 2023-11-23 Vir Biotechnology, Inc. Naphthyridine based enpp1 modulators and uses thereof
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