TW201930353A - 使用經靶向之ox40促效劑的組合療法 - Google Patents

使用經靶向之ox40促效劑的組合療法 Download PDF

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TW201930353A
TW201930353A TW107138607A TW107138607A TW201930353A TW 201930353 A TW201930353 A TW 201930353A TW 107138607 A TW107138607 A TW 107138607A TW 107138607 A TW107138607 A TW 107138607A TW 201930353 A TW201930353 A TW 201930353A
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seq
amino acid
acid sequence
cdr
variable region
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TW107138607A
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瑪莉娜 貝卡克
瑞秋 珊卓 葛洛
克里斯俊 克雷恩
喬翰尼斯 山姆
帕伯羅 優瑪那
賽嬪 藍
瑪麗亞 阿曼
慕帝塔 品洽
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瑞士商赫孚孟拉羅股份公司
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007Carcino-embryonic Antigens
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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TW107138607A 2017-11-01 2018-10-31 使用經靶向之ox40促效劑的組合療法 TW201930353A (zh)

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??17199542.6 2017-11-01
EP17199542 2017-11-01

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US (1) US20200392237A1 (cg-RX-API-DMAC7.html)
EP (1) EP3704155A2 (cg-RX-API-DMAC7.html)
JP (1) JP2021501162A (cg-RX-API-DMAC7.html)
KR (1) KR20200084006A (cg-RX-API-DMAC7.html)
CN (1) CN111315781A (cg-RX-API-DMAC7.html)
AU (1) AU2018359506A1 (cg-RX-API-DMAC7.html)
BR (1) BR112020007630A2 (cg-RX-API-DMAC7.html)
CA (1) CA3079036A1 (cg-RX-API-DMAC7.html)
IL (1) IL273770A (cg-RX-API-DMAC7.html)
MX (1) MX2020004573A (cg-RX-API-DMAC7.html)
TW (1) TW201930353A (cg-RX-API-DMAC7.html)
WO (1) WO2019086497A2 (cg-RX-API-DMAC7.html)

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WO2019086497A3 (en) 2019-06-20
IL273770A (en) 2020-05-31
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JP2021501162A (ja) 2021-01-14
AU2018359506A1 (en) 2020-04-23
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US20200392237A1 (en) 2020-12-17
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