TW201821080A - 用於治療發炎性疾病之化合物及其醫藥組合物 - Google Patents

用於治療發炎性疾病之化合物及其醫藥組合物 Download PDF

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Publication number
TW201821080A
TW201821080A TW106139074A TW106139074A TW201821080A TW 201821080 A TW201821080 A TW 201821080A TW 106139074 A TW106139074 A TW 106139074A TW 106139074 A TW106139074 A TW 106139074A TW 201821080 A TW201821080 A TW 201821080A
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Taiwan
Prior art keywords
compound
treatment
pharmaceutically acceptable
acceptable salt
biomarker
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TW106139074A
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English (en)
Chinese (zh)
Inventor
尚塔爾 特雷瑟 塔塞
斐勒 哈里森
雷內 亞歷山大 蓋倫
約翰 沙傑特 桑帝
約翰 G 麥哈奇森
湯瑪斯 奧賴爾登
尼路法 莫薩費里安
奧托 迪內希 佩托
提摩西 R 沃特金斯
大衛 L 勾薩居
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比利時商葛萊伯格有限公司
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Publication of TW201821080A publication Critical patent/TW201821080A/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW106139074A 2016-11-10 2017-11-10 用於治療發炎性疾病之化合物及其醫藥組合物 TW201821080A (zh)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
??1618963.1 2016-11-10
??1618961.5 2016-11-10
??1618960.7 2016-11-10
GB201618960 2016-11-10
??1618959.9 2016-11-10
GB201618964 2016-11-10
??1618964.9 2016-11-10
GB201618963 2016-11-10
GB201618962 2016-11-10
GB201618959 2016-11-10
??1618962.3 2016-11-10
GB201618961 2016-11-10

Publications (1)

Publication Number Publication Date
TW201821080A true TW201821080A (zh) 2018-06-16

Family

ID=60388032

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106139074A TW201821080A (zh) 2016-11-10 2017-11-10 用於治療發炎性疾病之化合物及其醫藥組合物

Country Status (8)

Country Link
US (1) US20190314382A1 (enExample)
EP (1) EP3538103A1 (enExample)
JP (1) JP2019534304A (enExample)
AU (1) AU2017358703A1 (enExample)
CA (1) CA3043396A1 (enExample)
RU (1) RU2019117562A (enExample)
TW (1) TW201821080A (enExample)
WO (1) WO2018087202A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282168A (zh) * 2022-08-30 2022-11-04 马应龙大健康有限公司 一种缓解婴幼儿湿疹症状的舒缓润肤霜及其制备方法和应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019132654A1 (en) * 2017-12-27 2019-07-04 Erasmus University Medical Center Rotterdam Methods of treating sarcoidosis
EP3810094A1 (en) 2018-06-20 2021-04-28 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor
WO2020009566A1 (en) * 2018-07-04 2020-01-09 Erasmus University Medical Center Rotterdam Methods of treating sarcoidosis
WO2020191041A2 (en) * 2019-03-19 2020-09-24 Incyte Corporation Biomarkers for vitiligo
US20200405627A1 (en) 2019-06-10 2020-12-31 Incyte Corporation Topical treatment of vitiligo by a jak inhibitor
WO2021076124A1 (en) * 2019-10-16 2021-04-22 Incyte Corporation Use of jak1 inhibitors for the treatment of cutaneous lupus erythematosus and lichen planus (lp)
US11992490B2 (en) 2019-10-16 2024-05-28 Incyte Corporation Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2530474C (en) 2003-07-03 2009-04-14 Japan Science And Technology Agency Remedy for sarcoidosis and method of treating the same
TWI462920B (zh) 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
DK2830662T3 (da) * 2012-03-29 2019-01-02 Univ Columbia Fremgangsmåder til behandlng af hårtabsforstyrrelser
MA37775A1 (fr) 2012-06-22 2017-04-28 Galapagos Nv Aminotriazolopyridine pour l'utilisation dans le traitement de l'inflammation, et compositions pharmaceutiques associées
CA2926361A1 (en) * 2013-10-24 2015-04-30 Abbvie Inc. Jak1 selective inhibitor and uses thereof
GB201402071D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201402070D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Pharmaceutical compositions for the treatment of inflammatory disorders
CN107438609B (zh) 2015-04-13 2020-10-09 加拉帕戈斯股份有限公司 用于治疗心血管障碍的方法
EP3283078A1 (en) 2015-04-13 2018-02-21 Galapagos NV Methods for the treatment of inflammatory disorders
CA2985185A1 (en) * 2015-05-07 2016-11-10 The Trustees Of Columbia University In The City Of New York Methods and compositions for promoting hair growth

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282168A (zh) * 2022-08-30 2022-11-04 马应龙大健康有限公司 一种缓解婴幼儿湿疹症状的舒缓润肤霜及其制备方法和应用
CN115282168B (zh) * 2022-08-30 2024-05-31 马应龙大健康有限公司 一种缓解婴幼儿湿疹症状的舒缓润肤霜及其制备方法和应用

Also Published As

Publication number Publication date
CA3043396A1 (en) 2018-05-17
RU2019117562A3 (enExample) 2021-02-09
JP2019534304A (ja) 2019-11-28
WO2018087202A1 (en) 2018-05-17
EP3538103A1 (en) 2019-09-18
RU2019117562A (ru) 2020-12-10
US20190314382A1 (en) 2019-10-17
AU2017358703A1 (en) 2019-05-09

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