JP2019534304A - 炎症性疾患の治療のための化合物及びその医薬組成物 - Google Patents

炎症性疾患の治療のための化合物及びその医薬組成物 Download PDF

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JP2019534304A
JP2019534304A JP2019524273A JP2019524273A JP2019534304A JP 2019534304 A JP2019534304 A JP 2019534304A JP 2019524273 A JP2019524273 A JP 2019524273A JP 2019524273 A JP2019524273 A JP 2019524273A JP 2019534304 A JP2019534304 A JP 2019534304A
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compound
pharmaceutically acceptable
acceptable salt
pharmaceutical composition
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JP2019534304A5 (enExample
Inventor
テレセ タスセット チャンタル
テレセ タスセット チャンタル
ハリソン ピルレ
ハリソン ピルレ
アレクサンドレ ガリエン レネ
アレクサンドレ ガリエン レネ
サージェント サンディ ジョン
サージェント サンディ ジョン
ジー. マクハッチソン ジョン
ジー. マクハッチソン ジョン
オリオーダン トーマス
オリオーダン トーマス
モザッファリアン ネールファー
モザッファリアン ネールファー
ディネシュ パテル ウプタル
ディネシュ パテル ウプタル
アール.ワトキンス ティモシー
アール. ワトキンス ティモシー
エル. ゴセージ デービッド
エル. ゴセージ デービッド
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Galapagos NV
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Galapagos NV
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Publication of JP2019534304A publication Critical patent/JP2019534304A/ja
Publication of JP2019534304A5 publication Critical patent/JP2019534304A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2019524273A 2016-11-10 2017-11-09 炎症性疾患の治療のための化合物及びその医薬組成物 Withdrawn JP2019534304A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB1618961.5 2016-11-10
GB1618963.1 2016-11-10
GB201618959 2016-11-10
GB1618959.9 2016-11-10
GB201618961 2016-11-10
GB201618962 2016-11-10
GB1618964.9 2016-11-10
GB1618960.7 2016-11-10
GB201618960 2016-11-10
GB1618962.3 2016-11-10
GB201618963 2016-11-10
GB201618964 2016-11-10
PCT/EP2017/078701 WO2018087202A1 (en) 2016-11-10 2017-11-09 Compounds and pharmaceutical compositions thereof for the treatment of inflammatory diseases

Publications (2)

Publication Number Publication Date
JP2019534304A true JP2019534304A (ja) 2019-11-28
JP2019534304A5 JP2019534304A5 (enExample) 2020-12-17

Family

ID=60388032

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019524273A Withdrawn JP2019534304A (ja) 2016-11-10 2017-11-09 炎症性疾患の治療のための化合物及びその医薬組成物

Country Status (8)

Country Link
US (1) US20190314382A1 (enExample)
EP (1) EP3538103A1 (enExample)
JP (1) JP2019534304A (enExample)
AU (1) AU2017358703A1 (enExample)
CA (1) CA3043396A1 (enExample)
RU (1) RU2019117562A (enExample)
TW (1) TW201821080A (enExample)
WO (1) WO2018087202A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019132654A1 (en) * 2017-12-27 2019-07-04 Erasmus University Medical Center Rotterdam Methods of treating sarcoidosis
US12171764B2 (en) 2018-06-20 2024-12-24 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a JAK or other kinase inhibitor
WO2020009566A1 (en) * 2018-07-04 2020-01-09 Erasmus University Medical Center Rotterdam Methods of treating sarcoidosis
EP3941474A2 (en) 2019-03-19 2022-01-26 Incyte Corporation Biomarkers for vitiligo
MA56215A (fr) 2019-06-10 2022-04-20 Incyte Corp Traitement topique du vitiligo par un inhibiteur de jak
JP7518900B2 (ja) * 2019-10-16 2024-07-18 インサイト・コーポレイション 皮膚エリテマトーデス及び扁平苔癬(lp)の治療のためのjak1阻害剤の使用
US11992490B2 (en) 2019-10-16 2024-05-28 Incyte Corporation Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
CN115282168B (zh) * 2022-08-30 2024-05-31 马应龙大健康有限公司 一种缓解婴幼儿湿疹症状的舒缓润肤霜及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005002623A1 (ja) 2003-07-03 2005-01-13 Japan Science And Technology Agency サルコイドーシスの治療薬と治療方法
TWI462920B (zh) 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
HUE040127T2 (hu) * 2012-03-29 2019-02-28 Univ Columbia Eljárások hajhullási rendellenességek kezelésére
UY34855A (es) 2012-06-22 2014-01-31 Galapagos Nv Aminotriazolopiridina para usar el tratamiento de la inflamación y composiciones farmacéuticas de ella.
CA2926361A1 (en) * 2013-10-24 2015-04-30 Abbvie Inc. Jak1 selective inhibitor and uses thereof
GB201402071D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201402070D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Pharmaceutical compositions for the treatment of inflammatory disorders
WO2016165953A1 (en) 2015-04-13 2016-10-20 Galapagos Nv Methods for the treatment of inflammatory disorders
WO2016165952A1 (en) 2015-04-13 2016-10-20 Galapagos Nv Methods for the treatment of cardiovascular disorders
AU2016259023A1 (en) * 2015-05-07 2017-11-30 The Trustees Of Columbia University In The City Of New York Methods and compositions for promoting hair growth

Also Published As

Publication number Publication date
CA3043396A1 (en) 2018-05-17
RU2019117562A3 (enExample) 2021-02-09
US20190314382A1 (en) 2019-10-17
RU2019117562A (ru) 2020-12-10
WO2018087202A1 (en) 2018-05-17
TW201821080A (zh) 2018-06-16
EP3538103A1 (en) 2019-09-18
AU2017358703A1 (en) 2019-05-09

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