TW201742633A - 使用ＣＤ３２ＢｘＣＤ７９Ｂ結合分子治療炎症性疾病和病症的方法 - Google Patents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/626—Diabody or triabody
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662346717P | 2016-06-07 | 2016-06-07 | |
| US201662432328P | 2016-12-09 | 2016-12-09 |
Publications (1)
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| TW201742633A true TW201742633A (zh) | 2017-12-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| TW106118941A TW201742633A (zh) | 2016-06-07 | 2017-06-07 | 使用ＣＤ３２ＢｘＣＤ７９Ｂ結合分子治療炎症性疾病和病症的方法 |
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| EP (1) | EP3464378A4 (enExample) |
| JP (3) | JP2019521103A (enExample) |
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| TW (1) | TW201742633A (enExample) |
| WO (1) | WO2017214096A1 (enExample) |
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| CU20170041A7 (es) * | 2014-09-26 | 2017-09-06 | Macrogenics Inc | Diacuerpos monovalentes biespecíficos que son capaces de unir cd19 y cd3 |
| US10995152B2 (en) * | 2016-10-26 | 2021-05-04 | The Board Of Trustees Of The Leland Stanford Junior University | Modified immunoglobulin hinge regions to reduce hemagglutination |
| KR20210071987A (ko) * | 2018-10-03 | 2021-06-16 | 네펜쓰 바이오사이언스, 엘엘씨 | 항-cd79 항체 및 이들의 용도 |
| EP4004052A4 (en) * | 2019-07-30 | 2023-11-01 | Provention Bio, Inc. | METHODS AND COMPOSITIONS FOR REDUCING IMMUNOGENICITY BY NON-DEPLETED B CELL INHIBITORS |
| AU2020323596A1 (en) * | 2019-07-30 | 2022-02-24 | Provention Bio, Inc. | Methods and compositions for reducing immunogenicity by non-depletional B cell inhibitors |
| US20240239912A1 (en) * | 2020-04-10 | 2024-07-18 | The Board Of Trustees Of The Leland Stanford Junior University | Targeted reduction of activated immune cells |
| KR20230113312A (ko) * | 2020-11-01 | 2023-07-28 | 프로벤션 바이오, 인코포레이티드 | 루푸스 치료 방법 및 조성물 |
| EP4382538A4 (en) * | 2021-08-02 | 2025-10-22 | Innovent Biologics Suzhou Co Ltd | BISPECIFIC ANTI-CD79BXCD3 ANTIBODY AND ITS USE |
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| US9284375B2 (en) * | 2005-04-15 | 2016-03-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9963510B2 (en) * | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| UA116479C2 (uk) * | 2013-08-09 | 2018-03-26 | Макродженікс, Інк. | БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ |
| US11384149B2 (en) * | 2013-08-09 | 2022-07-12 | Macrogenics, Inc. | Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof |
| AU2016207758C1 (en) * | 2015-01-13 | 2020-05-28 | Agresearch Limited | Agricultural composition |
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| CN109311990A (zh) | 2019-02-05 |
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| MX2024005841A (es) | 2024-05-27 |
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| MX2018015265A (es) | 2019-09-06 |
| JP2019521103A (ja) | 2019-07-25 |
| KR20250021614A (ko) | 2025-02-13 |
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