TW200616971A - Condensed tricyclic benzimidazoles - Google Patents

Condensed tricyclic benzimidazoles

Info

Publication number
TW200616971A
TW200616971A TW094134552A TW94134552A TW200616971A TW 200616971 A TW200616971 A TW 200616971A TW 094134552 A TW094134552 A TW 094134552A TW 94134552 A TW94134552 A TW 94134552A TW 200616971 A TW200616971 A TW 200616971A
Authority
TW
Taiwan
Prior art keywords
condensed tricyclic
tricyclic benzimidazoles
benzimidazoles
gastric
condensed
Prior art date
Application number
TW094134552A
Other languages
English (en)
Inventor
Christof Brehm
Peter Jan Zimmermann
Wilm Buhr
M Vittoria Chiesa
Andreas Palmer
Stefan Postius
Wolfgang Kromer
Wolfgang-Alexander Simon
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of TW200616971A publication Critical patent/TW200616971A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW094134552A 2004-10-04 2005-10-03 Condensed tricyclic benzimidazoles TW200616971A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04104851 2004-10-04

Publications (1)

Publication Number Publication Date
TW200616971A true TW200616971A (en) 2006-06-01

Family

ID=34929655

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094134552A TW200616971A (en) 2004-10-04 2005-10-03 Condensed tricyclic benzimidazoles

Country Status (7)

Country Link
US (1) US20080113962A1 (zh)
EP (1) EP1799681A1 (zh)
AR (1) AR051041A1 (zh)
AU (1) AU2005291295A1 (zh)
CA (1) CA2582294A1 (zh)
TW (1) TW200616971A (zh)
WO (1) WO2006037759A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0717102A2 (pt) * 2006-09-21 2013-10-29 Raqualia Pharma Inc Derivados de benzimidazol como inibidores seletivos de bomba de ácido
ES2365560T3 (es) * 2006-09-21 2011-10-06 Raqualia Pharma Inc Derivados de bencilmidazoles como inhibidores selectivos de bombas de ácido.
WO2008114123A1 (en) * 2007-03-21 2008-09-25 Raqualia Pharma Inc. Spiro benzimidazole derivatives as acid pump inhibitors
WO2011004882A1 (ja) 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
US9593125B2 (en) * 2012-07-27 2017-03-14 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto
AR103598A1 (es) 2015-02-02 2017-05-24 Forma Therapeutics Inc Ácidos bicíclicos[4,6,0]hidroxámicos como inhibidores de hdac
AU2016215432B2 (en) 2015-02-02 2020-07-30 Valo Early Discovery, Inc. 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
US10555935B2 (en) 2016-06-17 2020-02-11 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds
KR20040023739A (ko) * 2001-08-10 2004-03-18 알타나 파마 아게 삼환식 이미다조피리딘

Also Published As

Publication number Publication date
AU2005291295A1 (en) 2006-04-13
AR051041A1 (es) 2006-12-13
EP1799681A1 (en) 2007-06-27
US20080113962A1 (en) 2008-05-15
CA2582294A1 (en) 2006-04-13
WO2006037759A1 (en) 2006-04-13

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